SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 TYR A 277
TYR A 180
MET A 201
VAL A 158
 None
 1.04A 1fduB-2horA:
undetectable		 1fduB-2horA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.92A 1jnoA-2horA:
undetectable		 1jnoA-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.92A 1jnoB-2horA:
undetectable		 1jnoB-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.96A 1jo4A-2horA:
undetectable		 1jo4A-2horA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.96A 1jo4B-2horA:
undetectable		 1jo4B-2horA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 PHE A 393
TYR A 363
PRO A 208
 None
 1.11A 1mcnA-2horA:
undetectable
1mcnB-2horA:
undetectable
1mcnP-2horA:
undetectable		 1mcnA-2horA:
18.74
1mcnB-2horA:
18.74
1mcnP-2horA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ILE A 109
LEU A 112
VAL A 116
 None
 0.47A 1mz9B-2horA:
undetectable		 1mz9B-2horA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 THR A 108
LEU A 112
VAL A 115
 None
 0.60A 1mz9E-2horA:
undetectable		 1mz9E-2horA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.91A 1ng8A-2horA:
undetectable		 1ng8A-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.90A 1ng8B-2horA:
undetectable		 1ng8B-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.90A 1nrmA-2horA:
undetectable		 1nrmA-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.90A 1nrmB-2horA:
undetectable		 1nrmB-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.89A 1nruA-2horA:
undetectable		 1nruA-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ALA A 186
VAL A 158
TRP A 182
 None
 0.89A 1nruB-2horA:
undetectable		 1nruB-2horA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 6 PHE A 164
ASN A 207
ARG A 169
GLY A 392
 None
SO4  A 600 (-3.9A)
None
None
 1.02A 1oniA-2horA:
undetectable
1oniB-2horA:
undetectable		 1oniA-2horA:
15.33
1oniB-2horA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 6 PHE A 164
ASN A 207
ARG A 169
GLY A 392
 None
SO4  A 600 (-3.9A)
None
None
 1.02A 1oniD-2horA:
undetectable
1oniF-2horA:
undetectable		 1oniD-2horA:
15.33
1oniF-2horA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 7 GLY A 392
PHE A 164
ASN A 207
ARG A 169
 None
None
SO4  A 600 (-3.9A)
None
 0.91A 1oniG-2horA:
undetectable
1oniI-2horA:
undetectable		 1oniG-2horA:
15.33
1oniI-2horA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ILE A 223
ILE A 199
THR A 203
 None
None
ACT  A 602 ( 4.1A)
 0.65A 1rg7A-2horA:
undetectable		 1rg7A-2horA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 9 LEU A 333
LEU A 418
VAL A  61
ALA A  62
PHE A 380
 None
 1.22A 1tbfA-2horA:
undetectable		 1tbfA-2horA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 5 HIS A 232
PRO A 231
TYR A 233
TYR A 229
 None
 1.18A 2ombA-2horA:
undetectable
2ombB-2horA:
undetectable		 2ombA-2horA:
19.71
2ombB-2horA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 LEU A 297
LEU A 264
PRO A 231
GLY A 117
 None
 1.01A 2po5A-2horA:
undetectable		 2po5A-2horA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 12 SER A  63
GLY A 390
ASP A 373
ARG A 338
PHE A 339
 None
 1.46A 3a27A-2horA:
undetectable		 3a27A-2horA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 12 TYR A 229
TYR A 228
ASP A 225
GLU A 242
ALA A 240
 None
None
ACT  A 602 (-2.7A)
None
None
 1.27A 4dmgA-2horA:
1.7		 4dmgA-2horA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_B_SAMB401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 11 TYR A 229
TYR A 228
ASP A 225
GLU A 242
ALA A 240
 None
None
ACT  A 602 (-2.7A)
None
None
 1.27A 4dmgB-2horA:
undetectable		 4dmgB-2horA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 12 GLY A 129
GLN A 134
LEU A 274
MET A 278
ILE A 126
 None
 0.94A 4okbA-2horA:
undetectable		 4okbA-2horA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 11 SER A 293
THR A 289
ALA A 263
THR A 253
GLY A 254
 None
 1.35A 4zjoD-2horA:
undetectable		 4zjoD-2horA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		3 / 3 ASP A 243
VAL A 270
LEU A 139
 None
 0.63A 5e5jB-2horA:
undetectable		 5e5jB-2horA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 12 PHE A 260
LEU A 294
ILE A 265
ILE A 109
LEU A 135
 None
 1.12A 5h8tA-2horA:
undetectable		 5h8tA-2horA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		5 / 12 LEU A 105
LEU A 246
ILE A 265
THR A 285
LEU A 274
 None
 1.34A 5ienA-2horA:
undetectable		 5ienA-2horA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 5 LEU A 143
VAL A 140
MET A 201
CYH A 220
 None
 1.30A 5te0A-2horA:
undetectable		 5te0A-2horA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 ILE A 329
TRP A 326
ARG A 325
TYR A 233
 None
 1.17A 6hisA-2horA:
undetectable
6hisB-2horA:
undetectable		 6hisA-2horA:
10.73
6hisB-2horA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 ILE A 329
TRP A 326
ARG A 325
TYR A 233
 None
 1.18A 6hisB-2horA:
undetectable
6hisC-2horA:
undetectable		 6hisB-2horA:
10.73
6hisC-2horA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 ILE A 329
TRP A 326
ARG A 325
TYR A 233
 None
 1.19A 6hisC-2horA:
undetectable
6hisD-2horA:
undetectable		 6hisC-2horA:
10.73
6hisD-2horA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 ILE A 329
TRP A 326
ARG A 325
TYR A 233
 None
 1.18A 6hisD-2horA:
undetectable
6hisE-2horA:
undetectable		 6hisD-2horA:
10.73
6hisE-2horA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 8 TYR A 233
ILE A 329
TRP A 326
ARG A 325
 None
 1.20A 6hisA-2horA:
undetectable
6hisE-2horA:
undetectable		 6hisA-2horA:
10.73
6hisE-2horA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2hor ALLIIN LYASE 1
(Allium
sativum) 		4 / 7 GLY A 131
ASN A 281
GLU A 283
GLY A 284
 SO4  A 601 (-3.4A)
None
None
None
 0.80A 6n7fA-2horA:
undetectable		 6n7fA-2horA:
11.46