SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 7 PHE A 371
VAL A 306
ILE A 393
GLY A 373
 None
None
None
UNX  A1212 ( 3.6A)
 0.96A 11gsA-2hp3A:
undetectable		 11gsA-2hp3A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.37A 1d4fA-2hp3A:
undetectable		 1d4fA-2hp3A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 1d4fB-2hp3A:
undetectable		 1d4fB-2hp3A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4D_B_TOYB501_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 9 ASP A 349
GLU A 320
SER A 324
ALA A 331
ASP A 314
 None
 1.48A 1m4dB-2hp3A:
0.0		 1m4dB-2hp3A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 156
THR A 154
ALA A 206
GLY A  98
HIS A  85
 None
None
None
UNX  A1201 (-3.3A)
None
 1.29A 1nbiC-2hp3A:
undetectable		 1nbiC-2hp3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 156
THR A 154
ALA A 206
GLY A  98
HIS A  85
 None
None
None
UNX  A1201 (-3.3A)
None
 1.29A 1nbiD-2hp3A:
undetectable		 1nbiD-2hp3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A 159
GLY A 156
ALA A 206
PHE A  93
TYR A 126
 None
 1.19A 1ri4A-2hp3A:
undetectable		 1ri4A-2hp3A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 5 GLY A 180
ILE A 181
VAL A 157
SER A 212
 None
 1.23A 1rs7A-2hp3A:
undetectable		 1rs7A-2hp3A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 1v8bA-2hp3A:
undetectable		 1v8bA-2hp3A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 1v8bB-2hp3A:
undetectable		 1v8bB-2hp3A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 1v8bC-2hp3A:
undetectable		 1v8bC-2hp3A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 1v8bD-2hp3A:
undetectable		 1v8bD-2hp3A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 7 GLY A 373
VAL A 306
ASP A 379
ARG A 392
 UNX  A1212 ( 3.6A)
None
None
EDO  A1005 (-4.2A)
 0.67A 2uyqA-2hp3A:
undetectable		 2uyqA-2hp3A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 THR A 162
ILE A 108
GLY A 159
ALA A 107
ALA A 134
 None
 1.13A 2yvlC-2hp3A:
undetectable		 2yvlC-2hp3A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 THR A 162
ILE A 108
GLY A 159
ALA A 107
ALA A 134
 None
 1.07A 2yvlD-2hp3A:
undetectable		 2yvlD-2hp3A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.33A 2zj0A-2hp3A:
undetectable		 2zj0A-2hp3A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 212
THR A 161
ALA A  77
ALA A 107
 None
 0.98A 3ax9B-2hp3A:
undetectable		 3ax9B-2hp3A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.28A 3ce6A-2hp3A:
undetectable		 3ce6A-2hp3A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.29A 3ce6C-2hp3A:
undetectable		 3ce6C-2hp3A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 10 VAL A 127
GLY A 129
PRO A 100
VAL A  95
LEU A   6
 None
 1.29A 3elzC-2hp3A:
undetectable		 3elzC-2hp3A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.23A 3g1uA-2hp3A:
undetectable		 3g1uA-2hp3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 3g1uB-2hp3A:
undetectable		 3g1uB-2hp3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.29A 3g1uC-2hp3A:
undetectable		 3g1uC-2hp3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 3g1uD-2hp3A:
undetectable		 3g1uD-2hp3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.25A 3glqA-2hp3A:
undetectable		 3glqA-2hp3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 3glqB-2hp3A:
undetectable		 3glqB-2hp3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 7 GLU A 113
HIS A 114
VAL A 115
VAL A 210
ALA A 107
 None
 1.28A 3kp6B-2hp3A:
undetectable		 3kp6B-2hp3A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.22A 3n58A-2hp3A:
undetectable		 3n58A-2hp3A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 212
THR A 161
ALA A  77
ALA A 107
 None
 0.94A 3ns1L-2hp3A:
undetectable		 3ns1L-2hp3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 331
GLY A 336
MET A 353
SER A 342
HIS A 347
 None
 1.33A 3pfgA-2hp3A:
undetectable		 3pfgA-2hp3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 10 PRO A 397
GLY A 373
TYR A 272
GLY A 280
ALA A 279
 None
UNX  A1212 ( 3.6A)
None
None
None
 1.40A 3pp7B-2hp3A:
undetectable		 3pp7B-2hp3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 5 GLY A 180
ILE A 181
VAL A 157
SER A 212
 None
 1.22A 4d33A-2hp3A:
undetectable		 4d33A-2hp3A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 5 GLY A 180
ILE A 181
VAL A 157
SER A 212
 None
 1.24A 4d33B-2hp3A:
undetectable		 4d33B-2hp3A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 103
ALA A  36
SER A 102
THR A  33
 None
 1.01A 4ikjA-2hp3A:
undetectable
4ikjB-2hp3A:
undetectable		 4ikjA-2hp3A:
15.76
4ikjB-2hp3A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 216
SER A 212
LEU A 166
ALA A 170
 None
 0.98A 4ikjA-2hp3A:
undetectable
4ikjB-2hp3A:
undetectable		 4ikjA-2hp3A:
15.76
4ikjB-2hp3A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A 166
ALA A 170
SER A 216
SER A 212
 None
 0.97A 4ikkA-2hp3A:
undetectable
4ikkB-2hp3A:
undetectable		 4ikkA-2hp3A:
15.76
4ikkB-2hp3A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 103
ALA A  36
SER A 102
THR A  33
 None
 1.00A 4iklA-2hp3A:
undetectable
4iklB-2hp3A:
undetectable		 4iklA-2hp3A:
15.76
4iklB-2hp3A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.29A 4lvcA-2hp3A:
undetectable		 4lvcA-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.31A 4lvcC-2hp3A:
undetectable		 4lvcC-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 6 PHE A 193
ASP A  88
HIS A  99
THR A 152
 UNX  A1206 (-4.5A)
None
UNX  A1201 (-3.6A)
UNX  A1207 ( 4.9A)
 1.37A 4paeA-2hp3A:
undetectable		 4paeA-2hp3A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		3 / 3 PRO A 277
VAL A 382
HIS A 383
 None
 0.85A 4pevC-2hp3A:
undetectable		 4pevC-2hp3A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.27A 4pfjA-2hp3A:
undetectable		 4pfjA-2hp3A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5axaA-2hp3A:
undetectable		 5axaA-2hp3A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.28A 5axaC-2hp3A:
undetectable		 5axaC-2hp3A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 4 ALA A 279
PRO A 403
LEU A 409
HIS A 408
 None
None
None
EDO  A1010 ( 3.8A)
 1.25A 5eskA-2hp3A:
undetectable		 5eskA-2hp3A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8A-2hp3A:
undetectable		 5hm8A-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8B-2hp3A:
undetectable		 5hm8B-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8C-2hp3A:
undetectable		 5hm8C-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8D-2hp3A:
undetectable		 5hm8D-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8E-2hp3A:
undetectable		 5hm8E-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8F-2hp3A:
undetectable		 5hm8F-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8G-2hp3A:
undetectable		 5hm8G-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5hm8H-2hp3A:
undetectable		 5hm8H-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.31A 5m5kA-2hp3A:
undetectable		 5m5kA-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.31A 5m5kC-2hp3A:
undetectable		 5m5kC-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.37A 5m66A-2hp3A:
undetectable		 5m66A-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.30A 5m66B-2hp3A:
undetectable		 5m66B-2hp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.29A 5utuF-2hp3A:
undetectable		 5utuF-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.28A 5utuH-2hp3A:
undetectable		 5utuH-2hp3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.34A 5v96A-2hp3A:
undetectable		 5v96A-2hp3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.31A 5v96B-2hp3A:
undetectable		 5v96B-2hp3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.32A 5v96C-2hp3A:
undetectable		 5v96C-2hp3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.34A 5v96D-2hp3A:
undetectable		 5v96D-2hp3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 8 ILE A 345
ASN A 328
LEU A 334
ALA A 331
 None
 0.86A 5y7pE-2hp3A:
undetectable		 5y7pE-2hp3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		3 / 3 LEU A  50
GLN A  47
LYS A  63
 None
None
EDO  A1016 ( 4.7A)
 0.96A 6exiB-2hp3A:
undetectable		 6exiB-2hp3A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		3 / 3 LEU A  50
GLN A  47
LYS A  63
 None
None
EDO  A1016 ( 4.7A)
 0.94A 6exiA-2hp3A:
undetectable		 6exiA-2hp3A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		4 / 4 LEU A 348
ASP A 314
PRO A 315
ARG A 316
 None
 0.92A 6fgdA-2hp3A:
undetectable		 6fgdA-2hp3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.28A 6gbnA-2hp3A:
undetectable		 6gbnA-2hp3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 263
ASP A  91
LEU A 104
GLY A 159
MET A  96
 None
 1.27A 6gbnD-2hp3A:
undetectable		 6gbnD-2hp3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 VAL A  79
ARG A  70
GLN A 445
PRO A 446
GLY A  66
 None
None
None
None
EDO  A1016 (-3.7A)
 1.46A 6gnfA-2hp3A:
undetectable		 6gnfA-2hp3A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 2hp3 IDS-EPIMERASE
(Agrobacterium
tumefaciens) 		5 / 12 VAL A  79
ARG A  70
GLN A 445
PRO A 446
GLY A  66
 None
None
None
None
EDO  A1016 (-3.7A)
 1.47A 6gnfC-2hp3A:
undetectable		 6gnfC-2hp3A:
22.43