SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		4 / 7 LEU A 105
LEU A  72
SER A  75
ASP A  93
 None
 1.04A 3lm8A-2hqrA:
undetectable
3lm8C-2hqrA:
2.3		 3lm8A-2hqrA:
21.95
3lm8C-2hqrA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		4 / 8 ASP A  93
LEU A 105
LEU A  72
SER A  75
 None
 0.92A 3lm8A-2hqrA:
undetectable
3lm8C-2hqrA:
2.4		 3lm8A-2hqrA:
21.95
3lm8C-2hqrA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		5 / 10 GLY A  90
ALA A  91
ILE A  69
VAL A  50
VAL A  73
 None
 1.12A 3nu9B-2hqrA:
undetectable		 3nu9B-2hqrA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		5 / 10 ILE A 172
VAL A 151
TYR A 212
ILE A 188
ILE A 191
 None
 1.16A 3p4wD-2hqrA:
undetectable		 3p4wD-2hqrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		5 / 10 ILE A 172
VAL A 151
TYR A 212
ILE A 188
ILE A 191
 None
 1.15A 3p4wE-2hqrA:
undetectable		 3p4wE-2hqrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		5 / 12 LEU A  72
SER A  74
LEU A  47
LEU A  20
ILE A 109
 None
 0.98A 4x1fA-2hqrA:
undetectable		 4x1fA-2hqrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		5 / 12 LEU A  72
SER A  74
LEU A  47
LEU A  20
ILE A 109
 None
 1.04A 4x1gA-2hqrA:
undetectable		 4x1gA-2hqrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		4 / 5 HIS A  85
VAL A  73
GLY A  90
ALA A  91
 None
 0.91A 5hwaA-2hqrA:
undetectable		 5hwaA-2hqrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2hqr PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Helicobacter
pylori) 		3 / 3 LEU A  47
ILE A 109
TYR A  99
 None
 0.47A 5uunB-2hqrA:
undetectable		 5uunB-2hqrA:
22.03