SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hti'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_A_SAMA501_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2hti	BH0577 PROTEIN (Bacillus halodurans)	5 / 12	ILE A 62 GLY A 59 ILE A 103 VAL A 71 ILE A 65	None FAD A 200 (-3.2A) None None None	0.97A	6emuA-2htiA: undetectable	6emuA-2htiA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_B_SAMB301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2hti	BH0577 PROTEIN (Bacillus halodurans)	5 / 12	ILE A 62 GLY A 59 ILE A 103 VAL A 71 ILE A 65	None FAD A 200 (-3.2A) None None None	0.94A	6emuB-2htiA: undetectable	6emuB-2htiA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EMU_C_SAMC301_0 (TRNA (GUANINE(9)-/ADENINE (9)-N1)-METHYLTRANSF ERASE)	2hti	BH0577 PROTEIN (Bacillus halodurans)	5 / 12	ILE A 62 GLY A 59 ILE A 103 VAL A 71 ILE A 65	None FAD A 200 (-3.2A) None None None	0.98A	6emuC-2htiA: undetectable	6emuC-2htiA: 19.28