SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2huj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.06A 1cqeA-2hujA:
2.2		 1cqeA-2hujA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.07A 1cqeB-2hujA:
0.5		 1cqeB-2hujA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		4 / 5 THR A 103
LEU A 107
VAL A 110
LEU A 114
 None
 0.77A 1fbmE-2hujA:
undetectable		 1fbmE-2hujA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 11 PHE A  87
ALA A  86
ALA A  83
LEU A  10
GLN A   9
 None
 1.19A 1hbpA-2hujA:
undetectable		 1hbpA-2hujA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		4 / 4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 None
 0.85A 1mz9D-2hujA:
undetectable		 1mz9D-2hujA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		4 / 7 VAL A 110
LEU A 114
ALA A  55
LEU A  72
 None
 0.85A 1pthA-2hujA:
undetectable		 1pthA-2hujA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		4 / 7 VAL A 110
LEU A 114
ALA A  55
LEU A  72
 None
 0.85A 1pthB-2hujA:
undetectable		 1pthB-2hujA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.06A 2aylA-2hujA:
undetectable		 2aylA-2hujA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.01A 3nt1A-2hujA:
undetectable		 3nt1A-2hujA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.02A 3nt1B-2hujA:
undetectable		 3nt1B-2hujA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		4 / 7 GLN A  74
LEU A  67
THR A 106
THR A  61
 None
 1.12A 4mbsA-2hujA:
3.2		 4mbsA-2hujA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 9 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.11A 4rs0A-2hujA:
2.7		 4rs0A-2hujA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.04A 5jvzA-2hujA:
undetectable		 5jvzA-2hujA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		5 / 12 VAL A 110
LEU A 114
LEU A 107
ALA A  55
LEU A  72
 None
 1.09A 5jvzB-2hujA:
undetectable		 5jvzB-2hujA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		3 / 3 LEU A  67
ASN A  78
LEU A  52
 None
 0.71A 6exiA-2hujA:
undetectable		 6exiA-2hujA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2huj LIN2004 PROTEIN
(Listeria
innocua) 		3 / 3 TYR A 100
ASP A  98
GLN A 101
 None
 0.91A 6g1pA-2hujA:
undetectable		 6g1pA-2hujA:
18.24