SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 8 ALA A 194
LEU A 152
LEU A 153
LEU A 164
ALA A  32
 None
 1.46A 1e7cA-2hvqA:
4.3		 1e7cA-2hvqA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		4 / 6 ASP A 292
ARG A 266
THR A 263
ASP A 113
 None
 1.24A 2j2pE-2hvqA:
undetectable
2j2pF-2hvqA:
undetectable		 2j2pE-2hvqA:
20.00
2j2pF-2hvqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		3 / 3 ASN A 269
ARG A 266
ASP A 110
 None
 0.75A 2qe6A-2hvqA:
undetectable		 2qe6A-2hvqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		3 / 3 ASN A 269
ARG A 266
ASP A 110
 None
 0.68A 2qe6B-2hvqA:
undetectable		 2qe6B-2hvqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		3 / 3 GLU A 296
ASP A 115
TYR A  75
 None
 0.78A 2yvlB-2hvqA:
undetectable		 2yvlB-2hvqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		4 / 4 LEU A 264
ASP A 180
VAL A 270
THR A 289
 None
 1.26A 3cyxB-2hvqA:
undetectable		 3cyxB-2hvqA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 ASN A  40
ARG A  55
PHE A 119
VAL A 207
LYS A 225
 APK  A  35 ( 3.7A)
APK  A  35 ( 2.8A)
APK  A  35 ( 3.7A)
APK  A  35 ( 4.1A)
APK  A  35 ( 3.4A)
 0.99A 3qwuA-2hvqA:
11.8		 3qwuA-2hvqA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		7 / 12 TYR A   5
ASN A  40
GLU A  99
PHE A 119
VAL A 207
LYS A 209
LYS A 225
 None
APK  A  35 ( 3.7A)
APK  A  35 ( 3.3A)
APK  A  35 ( 3.7A)
APK  A  35 ( 4.1A)
None
APK  A  35 ( 3.4A)
 0.58A 3qwuA-2hvqA:
11.8		 3qwuA-2hvqA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_B_ADNB501_1
(DNA LIGASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 11 ASN A  40
ARG A  55
GLU A  99
PHE A 119
VAL A 207
 APK  A  35 ( 3.7A)
APK  A  35 ( 2.8A)
APK  A  35 ( 3.3A)
APK  A  35 ( 3.7A)
APK  A  35 ( 4.1A)
 0.91A 3qwuB-2hvqA:
13.2		 3qwuB-2hvqA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_B_ADNB501_1
(DNA LIGASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		6 / 11 TYR A   5
ASN A  40
GLU A  99
PHE A 119
VAL A 207
LYS A 209
 None
APK  A  35 ( 3.7A)
APK  A  35 ( 3.3A)
APK  A  35 ( 3.7A)
APK  A  35 ( 4.1A)
None
 0.55A 3qwuB-2hvqA:
13.2		 3qwuB-2hvqA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		3 / 3 SER A 140
PHE A 145
LYS A 146
 None
 0.97A 3u88A-2hvqA:
undetectable		 3u88A-2hvqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 GLY A 287
THR A 289
VAL A 267
ILE A 271
VAL A 270
 None
 1.07A 4c9lA-2hvqA:
undetectable		 4c9lA-2hvqA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 GLY A 287
THR A 289
VAL A 267
ILE A 271
VAL A 270
 None
 1.04A 4c9oA-2hvqA:
3.6		 4c9oA-2hvqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 GLY A 287
THR A 289
VAL A 267
ILE A 271
VAL A 270
 None
 1.04A 4c9oB-2hvqA:
undetectable		 4c9oB-2hvqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		4 / 5 GLY A  38
THR A  39
GLY A 102
GLU A  99
 None
None
None
APK  A  35 ( 3.3A)
 1.17A 4v20A-2hvqA:
undetectable		 4v20A-2hvqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 GLU A 246
LEU A 317
GLU A 249
GLY A 256
ALA A 259
 None
 1.23A 4xe5A-2hvqA:
2.2		 4xe5A-2hvqA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y9T_A_PA1A401_1
(ABC TRANSPORTER,
SOLUTE BINDING
PROTEIN)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 12 ASP A 180
ASP A 113
ASP A 292
HIS A 181
ASN A 265
 None
 1.28A 4y9tA-2hvqA:
0.0		 4y9tA-2hvqA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BR1_A_X6XA401_1
(ABC TRANSPORTER,
BINDING PROTEIN)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 11 ASP A 180
ASP A 113
ASP A 292
HIS A 181
ASN A 265
 None
 1.23A 5br1A-2hvqA:
0.0		 5br1A-2hvqA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION
(Escherichia
virus
T4) 		5 / 7 GLY A 287
THR A 289
VAL A 267
ILE A 271
VAL A 270
 None
 1.26A 5ik1A-2hvqA:
undetectable		 5ik1A-2hvqA:
22.84