SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 2hvv DEOXYCYTIDYLATE
DEAMINASE
(Streptococcus
mutans) 		5 / 12 GLY A  46
GLY A  47
VAL A  94
PRO A  98
LEU A 106
 SO4  A 151 ( 4.0A)
SO4  A 151 (-4.6A)
None
None
None
 1.09A 3m6vB-2hvvA:
undetectable		 3m6vB-2hvvA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 2hvv DEOXYCYTIDYLATE
DEAMINASE
(Streptococcus
mutans) 		6 / 12 GLY A  46
GLY A  47
VAL A  94
PRO A  98
VAL A 111
LEU A 106
 SO4  A 151 ( 4.0A)
SO4  A 151 (-4.6A)
None
None
None
None
 1.15A 3m6wA-2hvvA:
undetectable		 3m6wA-2hvvA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2hvv DEOXYCYTIDYLATE
DEAMINASE
(Streptococcus
mutans) 		5 / 11 THR A  23
GLN A  79
GLY A  47
ALA A  49
THR A  51
 None
None
SO4  A 151 (-4.6A)
SO4  A 151 ( 4.7A)
None
 1.36A 4qvqH-2hvvA:
undetectable
4qvqI-2hvvA:
undetectable		 4qvqH-2hvvA:
19.64
4qvqI-2hvvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2hvv DEOXYCYTIDYLATE
DEAMINASE
(Streptococcus
mutans) 		5 / 11 THR A  23
GLN A  79
GLY A  47
ALA A  49
THR A  51
 None
None
SO4  A 151 (-4.6A)
SO4  A 151 ( 4.7A)
None
 1.36A 4qvqV-2hvvA:
undetectable
4qvqW-2hvvA:
undetectable		 4qvqV-2hvvA:
19.64
4qvqW-2hvvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2hvv DEOXYCYTIDYLATE
DEAMINASE
(Streptococcus
mutans) 		3 / 3 SER A  19
LYS A  20
SER A  22
 None
 0.72A 6az3P-2hvvA:
undetectable		 6az3P-2hvvA:
15.56