SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hx1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		4 / 8 ASP A 169
THR A 236
HIS A 235
ILE A 238
 EPE  A 307 (-3.7A)
None
None
None
 1.01A 1ei6C-2hx1A:
undetectable		 1ei6C-2hx1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		5 / 8 ALA A  55
LEU A 138
ILE A 164
VAL A  99
ILE A 116
 None
 1.41A 2uxpA-2hx1A:
undetectable		 2uxpA-2hx1A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		5 / 10 SER A  82
GLY A  83
ALA A  55
ILE A 199
ILE A 164
 None
 1.10A 4dt8B-2hx1A:
undetectable		 4dt8B-2hx1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		4 / 8 ALA A 279
THR A  37
LEU A  10
LEU A   9
 None
 0.90A 4ejgB-2hx1A:
undetectable		 4ejgB-2hx1A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		4 / 8 ILE A 161
LEU A 156
ILE A 199
PHE A 198
 None
 0.86A 4hb8A-2hx1A:
undetectable		 4hb8A-2hx1A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY
(Cytophaga
hutchinsonii) 		5 / 12 LEU A 135
ALA A  55
ILE A 190
ARG A 197
GLY A 195
 None
None
None
None
CL  A 306 ( 4.2A)
 1.12A 4l9qA-2hx1A:
undetectable		 4l9qA-2hx1A:
19.45