SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hx6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2hx6 RIBONUCLEASE
(Escherichia
virus
T4) 		4 / 7 TYR A  45
ILE A  54
PHE A  64
ALA A 134
 None
 1.05A 1oniD-2hx6A:
undetectable
1oniE-2hx6A:
undetectable		 1oniD-2hx6A:
25.14
1oniE-2hx6A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2hx6 RIBONUCLEASE
(Escherichia
virus
T4) 		4 / 6 PHE A  64
ALA A 134
TYR A  45
ILE A  54
 None
 1.09A 1oniH-2hx6A:
undetectable
1oniI-2hx6A:
undetectable		 1oniH-2hx6A:
25.14
1oniI-2hx6A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 2hx6 RIBONUCLEASE
(Escherichia
virus
T4) 		5 / 12 ILE A 106
LEU A 129
PHE A 115
ILE A  25
ILE A  70
 None
 1.20A 1re7B-2hx6A:
undetectable		 1re7B-2hx6A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2hx6 RIBONUCLEASE
(Escherichia
virus
T4) 		5 / 10 GLY A 109
ASP A 108
ILE A 150
VAL A 149
LEU A 113
 None
 1.23A 3ay0B-2hx6A:
undetectable		 3ay0B-2hx6A:
16.81