SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  63
HIS A  98
HIS A  23
 MN  A 555 (-2.6A)
CAC  A 400 (-4.0A)
FE  A 444 ( 3.4A)
 0.66A 1oe1A-2hypA:
undetectable		 1oe1A-2hypA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  63
HIS A  98
HIS A  23
 MN  A 555 (-2.6A)
CAC  A 400 (-4.0A)
FE  A 444 ( 3.4A)
 0.66A 1oe3A-2hypA:
undetectable		 1oe3A-2hypA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 8 TYR A  73
ASP A  99
ASP A  63
LEU A  91
 None
None
MN  A 555 (-2.6A)
None
 1.21A 1pk2A-2hypA:
undetectable		 1pk2A-2hypA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 1v54A-2hypA:
undetectable
1v54C-2hypA:
undetectable		 1v54A-2hypA:
20.49
1v54C-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 1v54N-2hypA:
undetectable
1v54P-2hypA:
undetectable		 1v54N-2hypA:
20.49
1v54P-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 2dyrN-2hypA:
0.4
2dyrP-2hypA:
undetectable		 2dyrN-2hypA:
20.49
2dyrP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.29A 2dysN-2hypA:
undetectable
2dysP-2hypA:
undetectable		 2dysN-2hypA:
20.49
2dysP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 2eijN-2hypA:
undetectable
2eijP-2hypA:
undetectable		 2eijN-2hypA:
20.49
2eijP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 2eikA-2hypA:
0.2
2eikC-2hypA:
undetectable		 2eikA-2hypA:
20.49
2eikC-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 2eikN-2hypA:
undetectable
2eikP-2hypA:
undetectable		 2eikN-2hypA:
20.49
2eikP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 2eilN-2hypA:
undetectable
2eilP-2hypA:
undetectable		 2eilN-2hypA:
20.49
2eilP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.35A 2eimN-2hypA:
undetectable
2eimP-2hypA:
undetectable		 2eimN-2hypA:
20.49
2eimP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 2einA-2hypA:
undetectable
2einC-2hypA:
undetectable		 2einA-2hypA:
20.49
2einC-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.33A 2einN-2hypA:
undetectable
2einP-2hypA:
undetectable		 2einN-2hypA:
20.49
2einP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		6 / 12 ALA A  57
ASP A  56
ILE A 165
ILE A  19
ALA A 167
ILE A 129
 None
 1.40A 2rkfB-2hypA:
undetectable		 2rkfB-2hypA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  63
HIS A  98
HIS A  23
 MN  A 555 (-2.6A)
CAC  A 400 (-4.0A)
FE  A 444 ( 3.4A)
 0.67A 2xxgA-2hypA:
undetectable		 2xxgA-2hypA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  63
HIS A  98
HIS A  23
 MN  A 555 (-2.6A)
CAC  A 400 (-4.0A)
FE  A 444 ( 3.4A)
 0.68A 2xxgC-2hypA:
undetectable		 2xxgC-2hypA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 3abkN-2hypA:
0.4
3abkP-2hypA:
undetectable		 3abkN-2hypA:
20.49
3abkP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 3abmN-2hypA:
undetectable
3abmP-2hypA:
undetectable		 3abmN-2hypA:
20.49
3abmP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.34A 3ag1N-2hypA:
undetectable
3ag1P-2hypA:
undetectable		 3ag1N-2hypA:
20.49
3ag1P-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.33A 3ag2N-2hypA:
undetectable
3ag2P-2hypA:
undetectable		 3ag2N-2hypA:
20.49
3ag2P-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 3ag4N-2hypA:
undetectable
3ag4P-2hypA:
undetectable		 3ag4N-2hypA:
20.49
3ag4P-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.33A 3asnA-2hypA:
undetectable
3asnC-2hypA:
undetectable		 3asnA-2hypA:
20.49
3asnC-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  94
LEU A 204
VAL A  59
ILE A 165
THR A 164
 None
 1.35A 3frqA-2hypA:
undetectable		 3frqA-2hypA:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 HIS A 170
HIS A 169
HIS A 207
 None
MN  A 555 (-3.3A)
MN  A 555 ( 3.3A)
 0.63A 3mihA-2hypA:
undetectable		 3mihA-2hypA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 190
ARG A 193
GLY A 192
LEU A 149
LEU A 195
 None
 1.16A 3wdmD-2hypA:
undetectable		 3wdmD-2hypA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 8 LEU A 149
LEU A 152
LEU A 156
VAL A 217
 None
 0.86A 4klaA-2hypA:
undetectable		 4klaA-2hypA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  23
VAL A  80
LEU A  41
 FE  A 444 ( 3.4A)
None
None
 0.70A 4m2vA-2hypA:
undetectable		 4m2vA-2hypA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  17
THR A 227
LEU A 251
SER A 262
 None
 0.98A 4pwjA-2hypA:
undetectable		 4pwjA-2hypA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 12 THR A 134
GLY A 206
GLY A  62
GLY A  96
SER A  20
 None
 0.98A 4uciA-2hypA:
undetectable		 4uciA-2hypA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 12 THR A 134
GLY A 206
GLY A  62
GLY A  96
SER A  20
 None
 0.98A 4uciB-2hypA:
undetectable		 4uciB-2hypA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 12 THR A 134
GLY A 206
GLY A  62
GLY A  96
SER A  20
 None
 0.97A 4uckA-2hypA:
undetectable		 4uckA-2hypA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.30A 5b1aN-2hypA:
undetectable
5b1aP-2hypA:
undetectable		 5b1aN-2hypA:
20.49
5b1aP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 5b1bN-2hypA:
undetectable
5b1bP-2hypA:
undetectable		 5b1bN-2hypA:
20.49
5b1bP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 5b3sN-2hypA:
undetectable
5b3sP-2hypA:
undetectable		 5b3sN-2hypA:
20.49
5b3sP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 4 ASP A  63
HIS A 169
HIS A 170
HIS A  98
 MN  A 555 (-2.6A)
MN  A 555 (-3.3A)
None
CAC  A 400 (-4.0A)
 1.32A 5ncdD-2hypA:
undetectable		 5ncdD-2hypA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 ASP A  63
HIS A  23
HIS A 209
HIS A 169
 MN  A 555 (-2.6A)
FE  A 444 ( 3.4A)
FE  A 444 ( 3.4A)
MN  A 555 (-3.3A)
 1.07A 5nelB-2hypA:
undetectable
5nelC-2hypA:
undetectable		 5nelB-2hypA:
21.48
5nelC-2hypA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 ASP A  63
HIS A  23
ASP A  21
HIS A 140
 MN  A 555 (-2.6A)
FE  A 444 ( 3.4A)
FE  A 444 (-3.1A)
None
 1.01A 5nnwD-2hypA:
undetectable		 5nnwD-2hypA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 ASP A  63
HIS A  23
ASP A  21
HIS A 140
 MN  A 555 (-2.6A)
FE  A 444 ( 3.4A)
FE  A 444 (-3.1A)
None
 1.02A 5no9D-2hypA:
undetectable		 5no9D-2hypA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		5 / 7 GLY A 192
LEU A 204
ILE A 144
LEU A 152
ILE A 129
 None
 1.25A 5vkqA-2hypA:
undetectable
5vkqB-2hypA:
undetectable		 5vkqA-2hypA:
10.53
5vkqB-2hypA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.31A 5x19N-2hypA:
undetectable
5x19P-2hypA:
undetectable		 5x19N-2hypA:
20.49
5x19P-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 5x1bN-2hypA:
undetectable
5x1bP-2hypA:
undetectable		 5x1bN-2hypA:
20.49
5x1bP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.34A 5x1fN-2hypA:
undetectable
5x1fP-2hypA:
undetectable		 5x1fN-2hypA:
20.49
5x1fP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.32A 5zcqN-2hypA:
undetectable
5zcqP-2hypA:
undetectable		 5zcqN-2hypA:
20.49
5zcqP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.33A 6nknA-2hypA:
undetectable
6nknC-2hypA:
undetectable		 6nknA-2hypA:
20.49
6nknC-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.40A 6nmfN-2hypA:
undetectable
6nmfP-2hypA:
undetectable		 6nmfN-2hypA:
20.49
6nmfP-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.38A 6nmpA-2hypA:
undetectable
6nmpC-2hypA:
undetectable		 6nmpA-2hypA:
20.49
6nmpC-2hypA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2hyp HYPOTHETICAL PROTEIN
RV0805
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 261
ASP A 257
THR A 258
TYR A 255
 None
BR  A 302 (-4.7A)
BR  A 302 ( 4.9A)
None
 1.39A 6nmpN-2hypA:
undetectable
6nmpP-2hypA:
undetectable		 6nmpN-2hypA:
20.49
6nmpP-2hypA:
21.29