SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hyx'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D1G_A_MTXA171_1 (DIHYDROFOLATE REDUCTASE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	5 / 12	LYS A 404 ILE A 514 LEU A 420 ILE A 462 THR A 466	None	1.32A	1d1gA-2hyxA: undetectable	1d1gA-2hyxA: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_A_ADNA1501_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 7	GLU A 527 LYS A 524 PRO A 509 ALA A 510	None	1.31A	2ejgA-2hyxA: undetectable	2ejgA-2hyxA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_B_ADNB1502_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 7	GLU A 527 LYS A 524 PRO A 509 ALA A 510	None	1.25A	2ejgB-2hyxA: undetectable	2ejgB-2hyxA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 6	GLU A 468 TYR A 572 LYS A 473 PRO A 467	None	1.25A	2vmyA-2hyxA: undetectable	2vmyA-2hyxA: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROZ_A_NCAA266_0 (APOLIPOPROTEIN A-I-BINDING PROTEIN)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 6	LEU A 629 ALA A 633 LEU A 567 THR A 568	None	1.05A	3rozA-2hyxA: undetectable	3rozA-2hyxA: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_A_W9TA1002_1 (HEMOLYTIC LECTIN CEL-III)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	3 / 3	ASP A 560 GLU A 527 GLY A 528	None	0.67A	3w9tA-2hyxA: undetectable	3w9tA-2hyxA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA502_0 (OXIDOREDUCTASE, FMN-BINDING)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 7	THR A 571 ASN A 630 LEU A 600 PHE A 573	None	1.37A	4awuA-2hyxA: undetectable	4awuA-2hyxA: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ4_A_ACTA403_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	3 / 3	VAL A 537 LEU A 541 VAL A 427	None	0.50A	4wq4A-2hyxA: undetectable	4wq4A-2hyxA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XYZ_A_ACTA103_0 (POLYUBIQUITIN-C)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 4	LEU A 657 ILE A 638 HIS A 666 VAL A 668	None	1.10A	4xyzA-2hyxA: undetectable	4xyzA-2hyxA: 11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_A_HFGA1003_1 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	3 / 3	GLU A 511 TRP A 450 HIS A 522	None	0.79A	5xipA-2hyxA: 2.5	5xipA-2hyxA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZMQ_I_PACI1_0 (SERINE PROTEASE NS3 SERINE PROTEASE SUBUNIT NS2B PEPTIDE PAC-DLY-DLY-DAR)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	3 / 3	VAL A 461 TYR A 451 GLU A 511	None	0.98A	5zmqD-2hyxA: undetectable 5zmqE-2hyxA: undetectable	5zmqD-2hyxA: 21.65 5zmqE-2hyxA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CP4_A_CAMA422_0 (CYTOCHROME P450CAM)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 8	LEU A 679 VAL A 668 VAL A 689 VAL A 640	None	1.06A	6cp4A-2hyxA: undetectable	6cp4A-2hyxA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_C_GMJC301_1 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	2hyx	PROTEIN DIPZ (Mycobacterium tuberculosis)	4 / 6	TRP A 508 TYR A 469 GLN A 441 GLU A 570	None	1.31A	6djzC-2hyxA: 2.6	6djzC-2hyxA: 21.45