SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2hzr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 5 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.12A 1t88B-2hzrA:
undetectable		 1t88B-2hzrA:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		5 / 7 THR A  34
ALA A  44
ASN A  58
TRP A 127
LEU A 129
 None
 0.96A 2hzqA-2hzrA:
30.6		 2hzqA-2hzrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		6 / 7 THR A  34
ALA A  44
TYR A  46
PHE A  89
TRP A 127
LEU A 129
 None
 0.46A 2hzqA-2hzrA:
30.6		 2hzqA-2hzrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 6 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.06A 2zawA-2hzrA:
undetectable		 2zawA-2hzrA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 6 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.06A 2zuhA-2hzrA:
undetectable		 2zuhA-2hzrA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 6 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.13A 4g3rB-2hzrA:
undetectable		 4g3rB-2hzrA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 6 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.14A 4kkyX-2hzrA:
undetectable		 4kkyX-2hzrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 5 TYR A  22
LEU A 129
VAL A 111
VAL A  87
 None
 1.15A 4l49A-2hzrA:
undetectable		 4l49A-2hzrA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		5 / 10 LEU A 101
LEU A 110
ASP A 124
SER A 113
ILE A 146
 None
 1.15A 4xj7C-2hzrA:
undetectable
4xj7D-2hzrA:
undetectable		 4xj7C-2hzrA:
19.63
4xj7D-2hzrA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2hzr APOLIPOPROTEIN D
(Homo
sapiens) 		4 / 7 ILE A 128
ILE A  32
THR A 148
ILE A 152
 None
 0.78A 5fukA-2hzrA:
undetectable
5fukB-2hzrA:
undetectable		 5fukA-2hzrA:
22.58
5fukB-2hzrA:
22.58