SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 2i02 GENERAL STRESS
PROTEIN OF COG3871
(Nostoc
punctiforme) 		4 / 4 LYS A  95
LEU A  93
ALA A 122
LEU A 124
 P33  A 201 (-3.3A)
None
P33  A 201 ( 3.9A)
None
 1.03A 1f86B-2i02A:
undetectable		 1f86B-2i02A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 2i02 GENERAL STRESS
PROTEIN OF COG3871
(Nostoc
punctiforme) 		3 / 3 THR A  27
SER A  37
PHE A  54
 None
 0.76A 3d4sA-2i02A:
undetectable		 3d4sA-2i02A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G59_A_ACTA306_0
(FMN
ADENYLYLTRANSFERASE)		 2i02 GENERAL STRESS
PROTEIN OF COG3871
(Nostoc
punctiforme) 		4 / 5 SER A  91
MET A  40
PHE A  26
ILE A  66
 None
FMN  A 200 (-4.8A)
None
None
 1.32A 3g59A-2i02A:
0.0		 3g59A-2i02A:
20.13