SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_3 (PHOSPHOLIPASE A2)	2i04	MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	3 / 3	PRO A 486 PHE A 519 LYS A 457	None	1.27A	3bjwG-2i04A: undetectable	3bjwG-2i04A: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1475_0 (MJ0495-LIKE PROTEIN)	2i04	MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	5 / 8	ILE A 499 ASP A 497 ILE A 478 SER A 458 GLY A 463	None None None SO4 A 901 (-3.9A) None	1.48A	4ac9C-2i04A: undetectable	4ac9C-2i04A: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0S_A_PX9A201_0 (BETA-LACTOGLOBULIN)	2i04	MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	5 / 12	VAL A 516 LEU A 530 LEU A 532 ILE A 499 LEU A 455	None	0.98A	4y0sA-2i04A: undetectable	4y0sA-2i04A: 16.67