SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i0i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2i0i DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 5 ARG A 464
LEU A 468
ILE A 479
PHE A 477
 None
 1.29A 3ln1D-2i0iA:
undetectable		 3ln1D-2i0iA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2i0i DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 11 GLY A 482
GLY A 485
SER A 513
GLU A 525
ALA A 527
 None
 1.03A 5o96G-2i0iA:
undetectable		 5o96G-2i0iA:
16.93