SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		5 / 11 LEU A  97
ILE A 101
VAL A 125
GLY A 120
SER A  65
 None
 1.16A 2bxeA-2i15A:
undetectable		 2bxeA-2i15A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		5 / 12 LEU A  97
ILE A 101
VAL A 125
GLY A 120
SER A  65
 None
 1.26A 2bxeB-2i15A:
undetectable		 2bxeB-2i15A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 6 MET A  57
ASP A  45
ASP A  44
TYR A  42
 None
 1.20A 2lh8A-2i15A:
undetectable		 2lh8A-2i15A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		3 / 3 TYR A  94
GLU A  43
ASP A  45
 None
 0.89A 3bxoB-2i15A:
undetectable		 3bxoB-2i15A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 7 PHE A 100
PHE A  62
ALA A  61
LEU A  54
 None
 1.00A 3t3sC-2i15A:
undetectable		 3t3sC-2i15A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 8 PHE A 100
PHE A  62
ALA A  61
LEU A  54
 None
 0.89A 4ejgB-2i15A:
undetectable		 4ejgB-2i15A:
14.78