SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2i2q COFILIN
(Schizosaccharomy
ces
pombe) 		5 / 12 CYH A  12
ALA A  15
GLU A  18
LEU A  25
PHE A  30
 None
 1.30A 1s9pB-2i2qA:
undetectable		 1s9pB-2i2qA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2i2q COFILIN
(Schizosaccharomy
ces
pombe) 		3 / 3 PRO A  88
ASP A 121
GLU A  59
 None
LDA  A 900 (-3.6A)
None
 0.79A 3v4tC-2i2qA:
undetectable		 3v4tC-2i2qA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2i2q COFILIN
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A  80
ILE A  82
ILE A 117
 None
None
EDO  A 304 ( 4.9A)
 0.67A 4y0qA-2i2qA:
undetectable		 4y0qA-2i2qA:
18.86