SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	2i2y	FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE/SERINE-RICH 3 (Streptococcus sp. 'group G'; Homo sapiens)	5 / 12	ARG A 92 TYR A 96 PHE A 94 GLY A 98 VAL A 115	None	1.11A	2zzmA-2i2yA: 2.9	2zzmA-2i2yA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	2i2y	FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE/SERINE-RICH 3 (Streptococcus sp. 'group G'; Homo sapiens)	5 / 12	ARG A 92 TYR A 96 PHE A 94 GLY A 98 VAL A 115	None	1.10A	2zznA-2i2yA: 2.3	2zznA-2i2yA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2i2y	FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE/SERINE-RICH 3 (Streptococcus sp. 'group G'; Homo sapiens)	5 / 9	GLY A 85 VAL A 103 GLY A 111 LEU A 81 PHE A 117	None	0.98A	5vkqC-2i2yA: undetectable 5vkqD-2i2yA: undetectable	5vkqC-2i2yA: 6.77 5vkqD-2i2yA: 6.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","2i2y","FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE\/SERINE-RICH 3","Streptococcus sp. 'group G';Homo sapiens",5,"ARG A  92;TYR A  96;PHE A  94;GLY A  98;VAL A 115","None","1.11A","2zzmA-2i2yA:2.9","2zzmA-2i2yA:19.06"],["2ZZN_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","2i2y","FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE\/SERINE-RICH 3","Streptococcus sp. 'group G';Homo sapiens",5,"ARG A  92;TYR A  96;PHE A  94;GLY A  98;VAL A 115","None","1.10A","2zznA-2i2yA:2.3","2zznA-2i2yA:19.06"],["5VKQ_C_PCFC1805_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","2i2y","FUSION PROTEIN CONSISTS OF IMMUNOGLOBULIN G-BINDING PROTEIN G AND SPLICING FACTOR, ARGININE\/SERINE-RICH 3","Streptococcus sp. 'group G';Homo sapiens",5,"GLY A  85;VAL A 103;GLY A 111;LEU A  81;PHE A 117","None","0.98A","5vkqC-2i2yA:undetectable;5vkqD-2i2yA:undetectable","5vkqC-2i2yA:6.77;5vkqD-2i2yA:6.77"]]