SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 2i39 PROTEIN N1
(Vaccinia
virus) 		5 / 11 LEU A  30
ASP A  35
ASP A  38
ILE A  75
ILE A  73
 None
 1.14A 3ebzB-2i39A:
undetectable		 3ebzB-2i39A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 2i39 PROTEIN N1
(Vaccinia
virus) 		3 / 3 TYR A  20
MET A   1
LEU A 113
 MPD  A 501 (-3.7A)
None
None
 0.94A 3vw1D-2i39A:
undetectable		 3vw1D-2i39A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 2i39 PROTEIN N1
(Vaccinia
virus) 		3 / 3 TRP A  11
ARG A  12
LEU A   4
 None
 0.91A 5dbyA-2i39A:
2.8		 5dbyA-2i39A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2i39 PROTEIN N1
(Vaccinia
virus) 		3 / 3 ARG A 100
ASN A  60
ASP A  52
 None
 0.77A 5gwxA-2i39A:
undetectable		 5gwxA-2i39A:
23.96