SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 HIS A 217
LEU A 199
LEU A 321
GLY A 192
 None
 1.02A 1a4lB-2i3aA:
undetectable		 1a4lB-2i3aA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.89A 1c9sL-2i3aA:
undetectable
1c9sM-2i3aA:
undetectable		 1c9sL-2i3aA:
12.78
1c9sM-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.89A 1c9sM-2i3aA:
undetectable
1c9sN-2i3aA:
undetectable		 1c9sM-2i3aA:
12.78
1c9sN-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.87A 1c9sN-2i3aA:
undetectable
1c9sO-2i3aA:
undetectable		 1c9sN-2i3aA:
12.78
1c9sO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.87A 1c9sP-2i3aA:
undetectable
1c9sQ-2i3aA:
undetectable		 1c9sP-2i3aA:
12.78
1c9sQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.87A 1c9sS-2i3aA:
undetectable
1c9sT-2i3aA:
undetectable		 1c9sS-2i3aA:
12.78
1c9sT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.89A 1c9sL-2i3aA:
undetectable
1c9sV-2i3aA:
undetectable		 1c9sL-2i3aA:
12.78
1c9sV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.94A 1gtfA-2i3aA:
undetectable
1gtfB-2i3aA:
undetectable		 1gtfA-2i3aA:
12.78
1gtfB-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  23
HIS A  59
ALA A  87
HIS A  58
 None
 0.79A 1gtfN-2i3aA:
undetectable
1gtfO-2i3aA:
undetectable		 1gtfN-2i3aA:
12.78
1gtfO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.87A 1gtfO-2i3aA:
undetectable
1gtfP-2i3aA:
undetectable		 1gtfO-2i3aA:
12.78
1gtfP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtfP-2i3aA:
undetectable
1gtfQ-2i3aA:
undetectable		 1gtfP-2i3aA:
12.78
1gtfQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtfQ-2i3aA:
undetectable
1gtfR-2i3aA:
undetectable		 1gtfQ-2i3aA:
12.78
1gtfR-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtfS-2i3aA:
undetectable
1gtfT-2i3aA:
undetectable		 1gtfS-2i3aA:
12.78
1gtfT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtfT-2i3aA:
undetectable
1gtfU-2i3aA:
undetectable		 1gtfT-2i3aA:
12.78
1gtfU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtfU-2i3aA:
undetectable
1gtfV-2i3aA:
undetectable		 1gtfU-2i3aA:
12.78
1gtfV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 1gtfL-2i3aA:
undetectable
1gtfV-2i3aA:
undetectable		 1gtfL-2i3aA:
12.78
1gtfV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 1gtnM-2i3aA:
undetectable
1gtnN-2i3aA:
undetectable		 1gtnM-2i3aA:
12.78
1gtnN-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtnN-2i3aA:
undetectable
1gtnO-2i3aA:
undetectable		 1gtnN-2i3aA:
12.78
1gtnO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.83A 1gtnR-2i3aA:
undetectable
1gtnS-2i3aA:
undetectable		 1gtnR-2i3aA:
12.78
1gtnS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1gtnT-2i3aA:
undetectable
1gtnU-2i3aA:
undetectable		 1gtnT-2i3aA:
12.78
1gtnU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.87A 1gtnU-2i3aA:
undetectable
1gtnV-2i3aA:
undetectable		 1gtnU-2i3aA:
12.78
1gtnV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 GLU A 222
HIS A 219
ASP A 112
 None
 0.89A 1i9gA-2i3aA:
3.6		 1i9gA-2i3aA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 THR A 290
ASN A 320
LEU A 321
ASP A 319
 None
 0.83A 1mxdA-2i3aA:
undetectable		 1mxdA-2i3aA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 THR A 290
ASN A 320
LEU A 321
ASP A 319
 None
 0.91A 1mxgA-2i3aA:
undetectable		 1mxgA-2i3aA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.89A 1utdM-2i3aA:
undetectable
1utdN-2i3aA:
undetectable		 1utdM-2i3aA:
12.78
1utdN-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 1utdN-2i3aA:
undetectable
1utdO-2i3aA:
undetectable		 1utdN-2i3aA:
12.78
1utdO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1utdO-2i3aA:
undetectable
1utdP-2i3aA:
undetectable		 1utdO-2i3aA:
12.78
1utdP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 1utdP-2i3aA:
undetectable
1utdQ-2i3aA:
undetectable		 1utdP-2i3aA:
12.78
1utdQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.83A 1utdR-2i3aA:
undetectable
1utdS-2i3aA:
undetectable		 1utdR-2i3aA:
12.78
1utdS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.83A 1utdS-2i3aA:
undetectable
1utdT-2i3aA:
undetectable		 1utdS-2i3aA:
12.78
1utdT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 1utdT-2i3aA:
undetectable
1utdU-2i3aA:
undetectable		 1utdT-2i3aA:
12.78
1utdU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.83A 1utdU-2i3aA:
undetectable
1utdV-2i3aA:
undetectable		 1utdU-2i3aA:
12.78
1utdV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 124
TYR A 125
LEU A 164
TYR A 135
ALA A 111
 None
 1.44A 2iyfB-2i3aA:
3.5		 2iyfB-2i3aA:
26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A  45
ILE A  25
ALA A  87
GLY A  79
LEU A  78
 None
 1.30A 2v0mB-2i3aA:
undetectable		 2v0mB-2i3aA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 110
GLY A  16
SER A  93
THR A  46
LEU A  45
 None
 1.15A 2wa2A-2i3aA:
undetectable		 2wa2A-2i3aA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 ARG A 193
GLY A  56
ALA A  66
HIS A  59
HIS A  61
 None
 1.39A 3boyA-2i3aA:
0.8
3boyC-2i3aA:
0.0		 3boyA-2i3aA:
19.24
3boyC-2i3aA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 HIS A  61
ARG A 193
GLY A  56
ALA A  66
HIS A  59
 None
 1.39A 3boyA-2i3aA:
0.8
3boyB-2i3aA:
0.9		 3boyA-2i3aA:
19.24
3boyB-2i3aA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA3001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 HIS A  61
ARG A 193
GLY A  56
ALA A  66
HIS A  59
 None
 1.40A 3boyB-2i3aA:
0.9
3boyC-2i3aA:
0.0		 3boyB-2i3aA:
19.24
3boyC-2i3aA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 LEU A 115
TRP A 121
GLY A 126
 None
 0.77A 3l35A-2i3aA:
undetectable
3l35H-2i3aA:
undetectable		 3l35A-2i3aA:
7.80
3l35H-2i3aA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 LEU A 115
TRP A 121
GLY A 126
 None
 0.74A 3l35B-2i3aA:
undetectable
3l35K-2i3aA:
undetectable		 3l35B-2i3aA:
7.80
3l35K-2i3aA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  71
LEU A  45
HIS A  81
GLY A  43
 None
 1.07A 3pp1A-2i3aA:
undetectable		 3pp1A-2i3aA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 ILE A 176
ALA A 172
ILE A 223
LEU A 167
TYR A 269
 None
 1.28A 3qg2B-2i3aA:
undetectable		 3qg2B-2i3aA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  29
VAL A  12
VAL A 330
LEU A  78
 None
 0.82A 3rgfA-2i3aA:
undetectable		 3rgfA-2i3aA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  79
GLY A  43
ALA A  13
ALA A  15
ALA A  17
 None
 0.93A 3sudA-2i3aA:
undetectable		 3sudA-2i3aA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  79
GLY A  43
ALA A  13
ALA A  17
SER A  18
 None
 1.02A 3sudD-2i3aA:
undetectable		 3sudD-2i3aA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 HIS A  67
LEU A  26
LEU A  30
TYR A  35
ALA A  17
 None
 1.07A 3vw7A-2i3aA:
undetectable		 3vw7A-2i3aA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 7 ALA A 314
ALA A 256
ALA A 170
PRO A 169
LEU A 167
 None
 1.30A 4du2B-2i3aA:
undetectable		 4du2B-2i3aA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A  68
LEU A  45
GLU A  71
 None
 0.67A 4l3gF-2i3aA:
0.5		 4l3gF-2i3aA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 PRO A 340
ASN A 334
HIS A  32
 BTB  A1400 (-4.3A)
None
BTB  A1400 (-4.6A)
 1.03A 4ma3H-2i3aA:
undetectable
4ma3L-2i3aA:
1.5		 4ma3H-2i3aA:
19.09
4ma3L-2i3aA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 152
TRP A 133
ILE A 106
 None
 0.88A 4mwxA-2i3aA:
undetectable		 4mwxA-2i3aA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		6 / 12 VAL A 182
ILE A 250
ALA A 162
LEU A 164
LEU A 167
LEU A 227
 None
 1.27A 4o1zA-2i3aA:
undetectable		 4o1zA-2i3aA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 ILE A 294
ASP A 319
GLY A 187
VAL A 185
 None
 1.03A 4oltB-2i3aA:
undetectable		 4oltB-2i3aA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  47
THR A  46
ALA A  17
GLY A  52
SER A  53
 None
 0.91A 4qvwK-2i3aA:
undetectable
4qvwL-2i3aA:
undetectable		 4qvwK-2i3aA:
21.53
4qvwL-2i3aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  47
THR A  46
ALA A  17
GLY A  52
SER A  53
 None
 0.92A 4qvwY-2i3aA:
undetectable
4qvwZ-2i3aA:
undetectable		 4qvwY-2i3aA:
21.53
4qvwZ-2i3aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 4 ILE A 250
ASN A 320
ILE A 294
VAL A 293
 None
 1.29A 4uy87-2i3aA:
undetectable		 4uy87-2i3aA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eeuC-2i3aA:
undetectable
5eeuD-2i3aA:
undetectable		 5eeuC-2i3aA:
12.78
5eeuD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eeuG-2i3aA:
undetectable
5eeuH-2i3aA:
undetectable		 5eeuG-2i3aA:
12.78
5eeuH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.93A 5eeuI-2i3aA:
undetectable
5eeuJ-2i3aA:
undetectable		 5eeuI-2i3aA:
12.78
5eeuJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeuN-2i3aA:
undetectable
5eeuO-2i3aA:
undetectable		 5eeuN-2i3aA:
12.78
5eeuO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eeuO-2i3aA:
undetectable
5eeuP-2i3aA:
undetectable		 5eeuO-2i3aA:
12.78
5eeuP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eeuP-2i3aA:
undetectable
5eeuQ-2i3aA:
undetectable		 5eeuP-2i3aA:
12.78
5eeuQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeuR-2i3aA:
undetectable
5eeuS-2i3aA:
undetectable		 5eeuR-2i3aA:
12.78
5eeuS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eeuS-2i3aA:
undetectable
5eeuT-2i3aA:
undetectable		 5eeuS-2i3aA:
12.78
5eeuT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eeuT-2i3aA:
undetectable
5eeuU-2i3aA:
undetectable		 5eeuT-2i3aA:
12.78
5eeuU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeuU-2i3aA:
undetectable
5eeuV-2i3aA:
undetectable		 5eeuU-2i3aA:
12.78
5eeuV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eevC-2i3aA:
undetectable
5eevD-2i3aA:
undetectable		 5eevC-2i3aA:
12.78
5eevD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eevG-2i3aA:
undetectable
5eevH-2i3aA:
undetectable		 5eevG-2i3aA:
12.78
5eevH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.92A 5eevI-2i3aA:
undetectable
5eevJ-2i3aA:
undetectable		 5eevI-2i3aA:
12.78
5eevJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eevN-2i3aA:
undetectable
5eevO-2i3aA:
undetectable		 5eevN-2i3aA:
12.78
5eevO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eevO-2i3aA:
undetectable
5eevP-2i3aA:
undetectable		 5eevO-2i3aA:
12.78
5eevP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eevP-2i3aA:
undetectable
5eevQ-2i3aA:
undetectable		 5eevP-2i3aA:
12.78
5eevQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eevR-2i3aA:
undetectable
5eevS-2i3aA:
undetectable		 5eevR-2i3aA:
12.78
5eevS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eevS-2i3aA:
undetectable
5eevT-2i3aA:
undetectable		 5eevS-2i3aA:
12.78
5eevT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eevT-2i3aA:
undetectable
5eevU-2i3aA:
undetectable		 5eevT-2i3aA:
12.78
5eevU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eevU-2i3aA:
undetectable
5eevV-2i3aA:
undetectable		 5eevU-2i3aA:
12.78
5eevV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eewC-2i3aA:
undetectable
5eewD-2i3aA:
undetectable		 5eewC-2i3aA:
12.78
5eewD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eewG-2i3aA:
undetectable
5eewH-2i3aA:
undetectable		 5eewG-2i3aA:
12.78
5eewH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.92A 5eewI-2i3aA:
undetectable
5eewJ-2i3aA:
undetectable		 5eewI-2i3aA:
12.78
5eewJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eewN-2i3aA:
undetectable
5eewO-2i3aA:
undetectable		 5eewN-2i3aA:
12.78
5eewO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eewO-2i3aA:
undetectable
5eewP-2i3aA:
undetectable		 5eewO-2i3aA:
12.78
5eewP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eewP-2i3aA:
undetectable
5eewQ-2i3aA:
undetectable		 5eewP-2i3aA:
12.78
5eewQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eewR-2i3aA:
undetectable
5eewS-2i3aA:
undetectable		 5eewR-2i3aA:
12.78
5eewS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eewS-2i3aA:
undetectable
5eewT-2i3aA:
undetectable		 5eewS-2i3aA:
12.78
5eewT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eewT-2i3aA:
undetectable
5eewU-2i3aA:
undetectable		 5eewT-2i3aA:
12.78
5eewU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eewU-2i3aA:
undetectable
5eewV-2i3aA:
undetectable		 5eewU-2i3aA:
12.78
5eewV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eexC-2i3aA:
undetectable
5eexD-2i3aA:
undetectable		 5eexC-2i3aA:
12.78
5eexD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eexG-2i3aA:
undetectable
5eexH-2i3aA:
undetectable		 5eexG-2i3aA:
12.78
5eexH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.92A 5eexI-2i3aA:
undetectable
5eexJ-2i3aA:
undetectable		 5eexI-2i3aA:
12.78
5eexJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.94A 5eexA-2i3aA:
undetectable
5eexK-2i3aA:
undetectable		 5eexA-2i3aA:
12.78
5eexK-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eexN-2i3aA:
undetectable
5eexO-2i3aA:
undetectable		 5eexN-2i3aA:
12.78
5eexO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eexO-2i3aA:
undetectable
5eexP-2i3aA:
undetectable		 5eexO-2i3aA:
12.78
5eexP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eexP-2i3aA:
undetectable
5eexQ-2i3aA:
undetectable		 5eexP-2i3aA:
12.78
5eexQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eexR-2i3aA:
undetectable
5eexS-2i3aA:
undetectable		 5eexR-2i3aA:
12.78
5eexS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eexS-2i3aA:
undetectable
5eexT-2i3aA:
undetectable		 5eexS-2i3aA:
12.78
5eexT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eexT-2i3aA:
undetectable
5eexU-2i3aA:
undetectable		 5eexT-2i3aA:
12.78
5eexU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eexU-2i3aA:
undetectable
5eexV-2i3aA:
undetectable		 5eexU-2i3aA:
12.78
5eexV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eeyC-2i3aA:
undetectable
5eeyD-2i3aA:
undetectable		 5eeyC-2i3aA:
12.78
5eeyD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eeyG-2i3aA:
undetectable
5eeyH-2i3aA:
undetectable		 5eeyG-2i3aA:
12.78
5eeyH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.93A 5eeyI-2i3aA:
undetectable
5eeyJ-2i3aA:
undetectable		 5eeyI-2i3aA:
12.78
5eeyJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeyN-2i3aA:
undetectable
5eeyO-2i3aA:
undetectable		 5eeyN-2i3aA:
12.78
5eeyO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eeyO-2i3aA:
undetectable
5eeyP-2i3aA:
undetectable		 5eeyO-2i3aA:
12.78
5eeyP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eeyP-2i3aA:
undetectable
5eeyQ-2i3aA:
undetectable		 5eeyP-2i3aA:
12.78
5eeyQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeyR-2i3aA:
undetectable
5eeyS-2i3aA:
undetectable		 5eeyR-2i3aA:
12.78
5eeyS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eeyS-2i3aA:
undetectable
5eeyT-2i3aA:
undetectable		 5eeyS-2i3aA:
12.78
5eeyT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eeyT-2i3aA:
undetectable
5eeyU-2i3aA:
undetectable		 5eeyT-2i3aA:
12.78
5eeyU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eeyU-2i3aA:
undetectable
5eeyV-2i3aA:
undetectable		 5eeyU-2i3aA:
12.78
5eeyV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5eezC-2i3aA:
undetectable
5eezD-2i3aA:
undetectable		 5eezC-2i3aA:
12.78
5eezD-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5eezG-2i3aA:
undetectable
5eezH-2i3aA:
undetectable		 5eezG-2i3aA:
12.78
5eezH-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.92A 5eezI-2i3aA:
undetectable
5eezJ-2i3aA:
undetectable		 5eezI-2i3aA:
12.78
5eezJ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  23
HIS A  59
ALA A  87
HIS A  58
 None
 0.78A 5eezL-2i3aA:
undetectable
5eezV-2i3aA:
undetectable		 5eezL-2i3aA:
12.78
5eezV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eezN-2i3aA:
undetectable
5eezO-2i3aA:
undetectable		 5eezN-2i3aA:
12.78
5eezO-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eezO-2i3aA:
undetectable
5eezP-2i3aA:
undetectable		 5eezO-2i3aA:
12.78
5eezP-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5eezP-2i3aA:
undetectable
5eezQ-2i3aA:
undetectable		 5eezP-2i3aA:
12.78
5eezQ-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eezR-2i3aA:
undetectable
5eezS-2i3aA:
undetectable		 5eezR-2i3aA:
12.78
5eezS-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5eezS-2i3aA:
undetectable
5eezT-2i3aA:
undetectable		 5eezS-2i3aA:
12.78
5eezT-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5eezT-2i3aA:
undetectable
5eezU-2i3aA:
undetectable		 5eezT-2i3aA:
12.78
5eezU-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5eezU-2i3aA:
undetectable
5eezV-2i3aA:
undetectable		 5eezU-2i3aA:
12.78
5eezV-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5ef0C-2i3aA:
undetectable
5ef0D-2i3aA:
undetectable		 5ef0C-2i3aA:
12.78
5ef0D-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5ef0G-2i3aA:
undetectable
5ef0H-2i3aA:
undetectable		 5ef0G-2i3aA:
12.78
5ef0H-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.93A 5ef0I-2i3aA:
undetectable
5ef0J-2i3aA:
undetectable		 5ef0I-2i3aA:
12.78
5ef0J-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.94A 5ef0A-2i3aA:
undetectable
5ef0K-2i3aA:
undetectable		 5ef0A-2i3aA:
12.78
5ef0K-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef0N-2i3aA:
undetectable
5ef0O-2i3aA:
undetectable		 5ef0N-2i3aA:
12.78
5ef0O-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef0O-2i3aA:
undetectable
5ef0P-2i3aA:
undetectable		 5ef0O-2i3aA:
12.78
5ef0P-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef0P-2i3aA:
undetectable
5ef0Q-2i3aA:
undetectable		 5ef0P-2i3aA:
12.78
5ef0Q-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef0R-2i3aA:
undetectable
5ef0S-2i3aA:
undetectable		 5ef0R-2i3aA:
12.78
5ef0S-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5ef0S-2i3aA:
undetectable
5ef0T-2i3aA:
undetectable		 5ef0S-2i3aA:
12.78
5ef0T-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5ef0T-2i3aA:
undetectable
5ef0U-2i3aA:
undetectable		 5ef0T-2i3aA:
12.78
5ef0U-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef0U-2i3aA:
undetectable
5ef0V-2i3aA:
undetectable		 5ef0U-2i3aA:
12.78
5ef0V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5ef1C-2i3aA:
undetectable
5ef1D-2i3aA:
undetectable		 5ef1C-2i3aA:
12.78
5ef1D-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5ef1G-2i3aA:
undetectable
5ef1H-2i3aA:
undetectable		 5ef1G-2i3aA:
12.78
5ef1H-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.93A 5ef1I-2i3aA:
undetectable
5ef1J-2i3aA:
undetectable		 5ef1I-2i3aA:
12.78
5ef1J-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  23
HIS A  59
ALA A  87
HIS A  58
 None
 0.78A 5ef1L-2i3aA:
undetectable
5ef1V-2i3aA:
undetectable		 5ef1L-2i3aA:
12.78
5ef1V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef1N-2i3aA:
undetectable
5ef1O-2i3aA:
undetectable		 5ef1N-2i3aA:
12.78
5ef1O-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef1O-2i3aA:
undetectable
5ef1P-2i3aA:
undetectable		 5ef1O-2i3aA:
12.78
5ef1P-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef1P-2i3aA:
undetectable
5ef1Q-2i3aA:
undetectable		 5ef1P-2i3aA:
12.78
5ef1Q-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef1R-2i3aA:
undetectable
5ef1S-2i3aA:
undetectable		 5ef1R-2i3aA:
12.78
5ef1S-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5ef1S-2i3aA:
undetectable
5ef1T-2i3aA:
undetectable		 5ef1S-2i3aA:
12.78
5ef1T-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5ef1T-2i3aA:
undetectable
5ef1U-2i3aA:
undetectable		 5ef1T-2i3aA:
12.78
5ef1U-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef1U-2i3aA:
undetectable
5ef1V-2i3aA:
undetectable		 5ef1U-2i3aA:
12.78
5ef1V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5ef2C-2i3aA:
undetectable
5ef2D-2i3aA:
undetectable		 5ef2C-2i3aA:
12.78
5ef2D-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5ef2G-2i3aA:
undetectable
5ef2H-2i3aA:
undetectable		 5ef2G-2i3aA:
12.78
5ef2H-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.93A 5ef2I-2i3aA:
undetectable
5ef2J-2i3aA:
undetectable		 5ef2I-2i3aA:
12.78
5ef2J-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  23
HIS A  59
ALA A  87
HIS A  58
 None
 0.78A 5ef2L-2i3aA:
undetectable
5ef2V-2i3aA:
undetectable		 5ef2L-2i3aA:
12.78
5ef2V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef2N-2i3aA:
undetectable
5ef2O-2i3aA:
undetectable		 5ef2N-2i3aA:
12.78
5ef2O-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef2O-2i3aA:
undetectable
5ef2P-2i3aA:
undetectable		 5ef2O-2i3aA:
12.78
5ef2P-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef2P-2i3aA:
undetectable
5ef2Q-2i3aA:
undetectable		 5ef2P-2i3aA:
12.78
5ef2Q-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef2R-2i3aA:
undetectable
5ef2S-2i3aA:
undetectable		 5ef2R-2i3aA:
12.78
5ef2S-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5ef2S-2i3aA:
undetectable
5ef2T-2i3aA:
undetectable		 5ef2S-2i3aA:
12.78
5ef2T-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5ef2T-2i3aA:
undetectable
5ef2U-2i3aA:
undetectable		 5ef2T-2i3aA:
12.78
5ef2U-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef2U-2i3aA:
undetectable
5ef2V-2i3aA:
undetectable		 5ef2U-2i3aA:
12.78
5ef2V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.95A 5ef3C-2i3aA:
undetectable
5ef3D-2i3aA:
undetectable		 5ef3C-2i3aA:
12.78
5ef3D-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.91A 5ef3G-2i3aA:
undetectable
5ef3H-2i3aA:
undetectable		 5ef3G-2i3aA:
12.78
5ef3H-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.92A 5ef3I-2i3aA:
undetectable
5ef3J-2i3aA:
undetectable		 5ef3I-2i3aA:
12.78
5ef3J-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.94A 5ef3A-2i3aA:
undetectable
5ef3K-2i3aA:
undetectable		 5ef3A-2i3aA:
12.78
5ef3K-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef3N-2i3aA:
undetectable
5ef3O-2i3aA:
undetectable		 5ef3N-2i3aA:
12.78
5ef3O-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef3O-2i3aA:
undetectable
5ef3P-2i3aA:
undetectable		 5ef3O-2i3aA:
12.78
5ef3P-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.88A 5ef3P-2i3aA:
undetectable
5ef3Q-2i3aA:
undetectable		 5ef3P-2i3aA:
12.78
5ef3Q-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef3R-2i3aA:
undetectable
5ef3S-2i3aA:
undetectable		 5ef3R-2i3aA:
12.78
5ef3S-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.85A 5ef3S-2i3aA:
undetectable
5ef3T-2i3aA:
undetectable		 5ef3S-2i3aA:
12.78
5ef3T-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.86A 5ef3T-2i3aA:
undetectable
5ef3U-2i3aA:
undetectable		 5ef3T-2i3aA:
12.78
5ef3U-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  23
HIS A  59
ALA A  87
HIS A  58
ILE A  25
 None
 0.84A 5ef3U-2i3aA:
undetectable
5ef3V-2i3aA:
undetectable		 5ef3U-2i3aA:
12.78
5ef3V-2i3aA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR A  20
TYR A 211
SER A 186
 None
 0.77A 5iktB-2i3aA:
undetectable		 5iktB-2i3aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 PRO A  89
ILE A  25
GLY A  22
GLY A  19
ALA A 326
 None
 0.90A 5o96A-2i3aA:
2.9
5o96B-2i3aA:
2.9		 5o96A-2i3aA:
19.05
5o96B-2i3aA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  28
ASP A 319
ARG A 144
PRO A 138
GLY A 136
 None
 1.31A 5syeB-2i3aA:
4.6		 5syeB-2i3aA:
20.45