SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ALA A  28
LEU A  52
ILE A 152
LEU A 199
THR A  60
 None
 1.13A 1qzfA-2i3dA:
undetectable		 1qzfA-2i3dA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ALA A  28
LEU A  52
ILE A 152
LEU A 199
THR A  60
 None
 1.13A 1qzfB-2i3dA:
undetectable		 1qzfB-2i3dA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ALA A  28
LEU A  52
ILE A 152
LEU A 199
THR A  60
 None
 1.13A 1qzfC-2i3dA:
undetectable		 1qzfC-2i3dA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ALA A  28
LEU A  52
ILE A 152
LEU A 199
THR A  60
 None
 1.12A 1qzfD-2i3dA:
undetectable		 1qzfD-2i3dA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ALA A  28
LEU A  52
ILE A 152
LEU A 199
THR A  60
 None
 1.12A 1qzfE-2i3dA:
undetectable		 1qzfE-2i3dA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 8 SER A  71
PHE A  63
LEU A  31
LEU A  82
 None
 0.91A 2bfpB-2i3dA:
6.6		 2bfpB-2i3dA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 8 SER A  71
PHE A  63
LEU A  31
LEU A  82
 None
 0.94A 2bfpC-2i3dA:
3.9		 2bfpC-2i3dA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 8 LEU A  61
ALA A  88
LEU A  31
GLY A 114
 None
 0.65A 2yfxA-2i3dA:
undetectable		 2yfxA-2i3dA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 7 ASP A  98
SER A  24
SER A 101
GLU A 125
 None
 1.23A 3bc9A-2i3dA:
undetectable		 3bc9A-2i3dA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 7 TYR A 107
MET A 200
LEU A  52
PHE A 192
 None
 1.09A 3nk2X-2i3dA:
undetectable		 3nk2X-2i3dA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 ILE A  68
ALA A  88
PHE A  63
ILE A 113
LEU A 117
 None
 1.09A 3w67C-2i3dA:
3.4		 3w67C-2i3dA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		4 / 8 VAL A  46
CYH A 203
ILE A  30
ILE A 130
 None
 0.98A 4afgD-2i3dA:
undetectable
4afgE-2i3dA:
undetectable		 4afgD-2i3dA:
22.26
4afgE-2i3dA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 12 SER A  67
GLY A  78
ASP A 138
PHE A 139
ILE A 113
 None
 1.05A 4pghD-2i3dA:
2.5		 4pghD-2i3dA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 11 LEU A 150
ALA A 105
LEU A  52
LEU A  49
LEU A 207
 None
 1.28A 4zn7B-2i3dA:
undetectable		 4zn7B-2i3dA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 2i3d HYPOTHETICAL PROTEIN
ATU1826
(Agrobacterium
fabrum) 		5 / 9 LEU A  31
GLY A 114
LEU A 117
LEU A  89
ALA A  85
 None
 1.06A 5dqfA-2i3dA:
1.4		 5dqfA-2i3dA:
16.79