SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2i3e G-RICH
(Carassius
auratus) 		4 / 8 THR A 108
PRO A 109
TYR A  59
LEU A  56
 None
 0.92A 1z2bB-2i3eA:
undetectable		 1z2bB-2i3eA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2i3e G-RICH
(Carassius
auratus) 		5 / 10 THR A 167
GLY A 168
GLY A 113
THR A 111
ILE A 106
 None
 1.10A 2y7wB-2i3eA:
undetectable		 2y7wB-2i3eA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2i3e G-RICH
(Carassius
auratus) 		4 / 8 LEU A 175
THR A 195
ALA A 104
ALA A 205
 None
 0.92A 3ax9B-2i3eA:
undetectable		 3ax9B-2i3eA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 2i3e G-RICH
(Carassius
auratus) 		4 / 7 ARG A 151
TYR A  84
ASP A 131
ALA A 130
 None
 1.14A 4zz8A-2i3eA:
undetectable		 4zz8A-2i3eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2i3e G-RICH
(Carassius
auratus) 		5 / 12 LEU A 100
LEU A 175
PRO A 147
PRO A 137
LEU A 140
 None
 1.27A 5xxiA-2i3eA:
undetectable		 5xxiA-2i3eA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2i3e G-RICH
(Carassius
auratus) 		4 / 7 TYR A 196
HIS A  42
LEU A 194
VAL A 187
 None
 1.23A 6g2pA-2i3eA:
undetectable		 6g2pA-2i3eA:
19.60