SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 5 PHE A  49
GLY A 148
THR A 126
PHE A 145
 None
 1.40A 1icvA-2i3fA:
undetectable
1icvB-2i3fA:
undetectable		 1icvA-2i3fA:
20.58
1icvB-2i3fA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 6 PHE A 104
VAL A  42
LEU A  43
PHE A  35
 None
 1.02A 1wrlB-2i3fA:
undetectable		 1wrlB-2i3fA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		5 / 12 ILE A 187
LEU A  97
ALA A  96
VAL A  24
LEU A 180
 None
 1.12A 3dzyA-2i3fA:
undetectable		 3dzyA-2i3fA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		5 / 11 TYR A 206
GLN A 207
TYR A 159
ILE A 173
ILE A 178
 None
 1.32A 3ganA-2i3fA:
undetectable		 3ganA-2i3fA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 5 LEU A  36
LYS A  66
GLN A  72
LEU A  67
 None
 1.00A 3h5gA-2i3fA:
undetectable
3h5gB-2i3fA:
undetectable		 3h5gA-2i3fA:
8.87
3h5gB-2i3fA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		5 / 9 VAL A  45
PHE A  12
ILE A 107
PHE A 176
VAL A 115
 None
 1.25A 3me6C-2i3fA:
undetectable		 3me6C-2i3fA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 7 GLY A  91
PHE A 190
PHE A 191
LEU A 196
 None
 0.74A 3v7pA-2i3fA:
undetectable		 3v7pA-2i3fA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		5 / 12 PRO A 153
LEU A 121
LEU A 114
LEU A 111
PHE A 176
 None
 1.14A 4a7aB-2i3fA:
undetectable		 4a7aB-2i3fA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 8 ALA A 139
SER A 138
ARG A 134
TYR A 129
 None
 1.10A 4ijiF-2i3fA:
undetectable		 4ijiF-2i3fA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		4 / 7 LEU A  98
VAL A  95
PRO A  89
GLU A 197
 None
 0.93A 4lb2A-2i3fA:
undetectable		 4lb2A-2i3fA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		3 / 3 ARG A 112
GLU A 204
ARG A 113
 None
 0.87A 4mwvA-2i3fA:
undetectable		 4mwvA-2i3fA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		3 / 3 ASN A  58
PHE A  53
TYR A 129
 None
 0.78A 4u15A-2i3fA:
2.7		 4u15A-2i3fA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		5 / 12 ALA A  70
LEU A  82
GLY A 202
THR A 132
PHE A  35
 None
 1.17A 5eshA-2i3fA:
undetectable		 5eshA-2i3fA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2i3f GLYCOLIPID
TRANSFER-LIKE
PROTEIN
(Galdieria
sulphuraria) 		3 / 3 LEU A 111
SER A 109
PHE A 110
 None
 0.62A 6fgcA-2i3fA:
undetectable		 6fgcA-2i3fA:
19.95