SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i5b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sA-2i5bA:
undetectable
1c9sK-2i5bA:
undetectable		 1c9sA-2i5bA:
18.03
1c9sK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1c9sA-2i5bA:
undetectable
1c9sB-2i5bA:
undetectable		 1c9sA-2i5bA:
18.03
1c9sB-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sB-2i5bA:
undetectable
1c9sC-2i5bA:
undetectable		 1c9sB-2i5bA:
18.03
1c9sC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1c9sC-2i5bA:
undetectable
1c9sD-2i5bA:
undetectable		 1c9sC-2i5bA:
18.03
1c9sD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1c9sD-2i5bA:
undetectable
1c9sE-2i5bA:
undetectable		 1c9sD-2i5bA:
18.03
1c9sE-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sE-2i5bA:
undetectable
1c9sF-2i5bA:
undetectable		 1c9sE-2i5bA:
18.03
1c9sF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sF-2i5bA:
undetectable
1c9sG-2i5bA:
undetectable		 1c9sF-2i5bA:
18.03
1c9sG-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1c9sG-2i5bA:
undetectable
1c9sH-2i5bA:
undetectable		 1c9sG-2i5bA:
18.03
1c9sH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sH-2i5bA:
undetectable
1c9sI-2i5bA:
undetectable		 1c9sH-2i5bA:
18.03
1c9sI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sJ-2i5bA:
undetectable
1c9sK-2i5bA:
undetectable		 1c9sJ-2i5bA:
18.03
1c9sK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sL-2i5bA:
undetectable
1c9sM-2i5bA:
undetectable		 1c9sL-2i5bA:
18.03
1c9sM-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sM-2i5bA:
undetectable
1c9sN-2i5bA:
undetectable		 1c9sM-2i5bA:
18.03
1c9sN-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1c9sO-2i5bA:
undetectable
1c9sP-2i5bA:
undetectable		 1c9sO-2i5bA:
18.03
1c9sP-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1c9sS-2i5bA:
undetectable
1c9sT-2i5bA:
undetectable		 1c9sS-2i5bA:
18.03
1c9sT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 8 SER A 250
ALA A 246
PHE A 242
ILE A 247
 None
None
None
ADP  A 301 (-4.3A)
 1.02A 1gm7A-2i5bA:
undetectable
1gm7B-2i5bA:
1.1		 1gm7A-2i5bA:
22.68
1gm7B-2i5bA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1gtfA-2i5bA:
undetectable
1gtfK-2i5bA:
undetectable		 1gtfA-2i5bA:
18.03
1gtfK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfA-2i5bA:
undetectable
1gtfB-2i5bA:
undetectable		 1gtfA-2i5bA:
18.03
1gtfB-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1gtfB-2i5bA:
undetectable
1gtfC-2i5bA:
undetectable		 1gtfB-2i5bA:
18.03
1gtfC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfC-2i5bA:
undetectable
1gtfD-2i5bA:
undetectable		 1gtfC-2i5bA:
18.03
1gtfD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfE-2i5bA:
undetectable
1gtfF-2i5bA:
undetectable		 1gtfE-2i5bA:
18.03
1gtfF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1gtfF-2i5bA:
undetectable
1gtfG-2i5bA:
undetectable		 1gtfF-2i5bA:
18.03
1gtfG-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfG-2i5bA:
undetectable
1gtfH-2i5bA:
undetectable		 1gtfG-2i5bA:
18.03
1gtfH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfH-2i5bA:
undetectable
1gtfI-2i5bA:
undetectable		 1gtfH-2i5bA:
18.03
1gtfI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtfI-2i5bA:
undetectable
1gtfJ-2i5bA:
undetectable		 1gtfI-2i5bA:
18.03
1gtfJ-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 1gtfO-2i5bA:
undetectable
1gtfP-2i5bA:
undetectable		 1gtfO-2i5bA:
18.03
1gtfP-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.32A 1gtfP-2i5bA:
undetectable
1gtfQ-2i5bA:
undetectable		 1gtfP-2i5bA:
18.03
1gtfQ-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 1gtfU-2i5bA:
undetectable
1gtfV-2i5bA:
undetectable		 1gtfU-2i5bA:
18.03
1gtfV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 1gtfL-2i5bA:
undetectable
1gtfV-2i5bA:
undetectable		 1gtfL-2i5bA:
18.03
1gtfV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1gtnA-2i5bA:
undetectable
1gtnB-2i5bA:
undetectable		 1gtnA-2i5bA:
18.03
1gtnB-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1gtnG-2i5bA:
undetectable
1gtnH-2i5bA:
undetectable		 1gtnG-2i5bA:
18.03
1gtnH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 MET A  35
GLN A  21
THR A  68
ILE A  69
LEU A  38
 None
 1.42A 1m2zD-2i5bA:
undetectable		 1m2zD-2i5bA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 8 THR A 139
LEU A 226
VAL A 222
VAL A 176
 None
 0.91A 1t86A-2i5bA:
undetectable		 1t86A-2i5bA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 1utdA-2i5bA:
undetectable
1utdB-2i5bA:
undetectable		 1utdA-2i5bA:
18.03
1utdB-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1utdB-2i5bA:
undetectable
1utdC-2i5bA:
undetectable		 1utdB-2i5bA:
18.03
1utdC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1utdC-2i5bA:
undetectable
1utdD-2i5bA:
undetectable		 1utdC-2i5bA:
18.03
1utdD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1utdD-2i5bA:
undetectable
1utdE-2i5bA:
undetectable		 1utdD-2i5bA:
18.03
1utdE-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1utdF-2i5bA:
undetectable
1utdG-2i5bA:
undetectable		 1utdF-2i5bA:
18.03
1utdG-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 1utdG-2i5bA:
undetectable
1utdH-2i5bA:
undetectable		 1utdG-2i5bA:
18.03
1utdH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 1utdJ-2i5bA:
undetectable
1utdK-2i5bA:
undetectable		 1utdJ-2i5bA:
18.03
1utdK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1utdA-2i5bA:
undetectable
1utdK-2i5bA:
undetectable		 1utdA-2i5bA:
18.03
1utdK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 1utdM-2i5bA:
undetectable
1utdN-2i5bA:
undetectable		 1utdM-2i5bA:
18.03
1utdN-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.32A 1utdN-2i5bA:
undetectable
1utdO-2i5bA:
undetectable		 1utdN-2i5bA:
18.03
1utdO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 8 ILE A  88
GLY A  11
ILE A  20
LEU A  66
 None
 0.77A 2o4nB-2i5bA:
undetectable		 2o4nB-2i5bA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		6 / 12 LEU A  66
ASP A  58
ILE A  57
ILE A  89
ALA A  37
ILE A  62
 None
 1.47A 2rkfB-2i5bA:
undetectable		 2rkfB-2i5bA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 THR A 139
PRO A 140
VAL A 175
ALA A 135
PRO A 108
 None
 1.45A 2v32A-2i5bA:
undetectable
2v32B-2i5bA:
undetectable		 2v32A-2i5bA:
22.30
2v32B-2i5bA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 PRO A 108
THR A 139
PRO A 140
VAL A 175
ALA A 135
 None
 1.42A 2v32A-2i5bA:
undetectable
2v32B-2i5bA:
undetectable		 2v32A-2i5bA:
22.30
2v32B-2i5bA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 THR A 139
PRO A 140
VAL A 175
ALA A 135
PRO A 108
 None
 1.44A 2v41A-2i5bA:
undetectable
2v41B-2i5bA:
undetectable		 2v41A-2i5bA:
22.30
2v41B-2i5bA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 PRO A 108
THR A 139
PRO A 140
VAL A 175
ALA A 135
 None
 1.43A 2v41A-2i5bA:
undetectable
2v41B-2i5bA:
undetectable		 2v41A-2i5bA:
22.30
2v41B-2i5bA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 6 CYH A 216
THR A 217
GLY A  19
ASP A  23
 None
 1.21A 3w9tE-2i5bA:
undetectable		 3w9tE-2i5bA:
21.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		9 / 11 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.43A 4c5lA-2i5bA:
39.8		 4c5lA-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		9 / 9 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.37A 4c5lB-2i5bA:
42.1		 4c5lB-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		9 / 10 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.45A 4c5lC-2i5bA:
40.9		 4c5lC-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		9 / 10 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.39A 4c5lD-2i5bA:
40.6		 4c5lD-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		7 / 7 GLY A  11
ASP A  13
GLY A  19
VAL A  42
MET A  82
HIS A 212
CYH A 216
 None
 0.40A 4c5nA-2i5bA:
41.7		 4c5nA-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		10 / 10 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
HIS A  52
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.37A 4c5nB-2i5bA:
42.1		 4c5nB-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		8 / 8 GLY A  11
ASP A  13
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.32A 4c5nC-2i5bA:
41.8		 4c5nC-2i5bA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		9 / 10 GLY A  11
ASP A  13
ALA A  18
GLY A  19
VAL A  42
MET A  82
VAL A 109
HIS A 212
CYH A 216
 None
 0.45A 4c5nD-2i5bA:
41.8		 4c5nD-2i5bA:
49.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 ASP A 194
ILE A 161
PRO A 140
THR A 139
VAL A 137
 None
 1.15A 4l1aA-2i5bA:
undetectable		 4l1aA-2i5bA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 LEU A 134
LEU A 131
LEU A 127
ALA A 126
LEU A  91
 None
 1.17A 4ltwA-2i5bA:
undetectable		 4ltwA-2i5bA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 LEU A 226
VAL A 105
GLY A  19
ASP A  23
PHE A  27
 None
 1.36A 4mubA-2i5bA:
2.1		 4mubA-2i5bA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 LEU A 127
ALA A  92
GLY A  81
ILE A  96
VAL A 105
 None
 0.88A 4nkxB-2i5bA:
undetectable		 4nkxB-2i5bA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 5 ASP A  13
VAL A 109
ASP A 107
GLY A 215
 None
None
None
ADP  A 301 (-3.2A)
 0.90A 4xp6A-2i5bA:
undetectable		 4xp6A-2i5bA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 LEU A  83
LEU A  38
GLY A  11
THR A   8
ILE A   9
 None
 1.17A 5b8hA-2i5bA:
1.8
5b8hB-2i5bA:
2.6		 5b8hA-2i5bA:
23.78
5b8hB-2i5bA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 8 ALA A 245
ASN A 268
HIS A 262
THR A 260
 None
 1.20A 5db5A-2i5bA:
undetectable
5db5B-2i5bA:
undetectable		 5db5A-2i5bA:
21.51
5db5B-2i5bA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 4 LEU A  38
ILE A  62
GLY A  11
ILE A  88
 None
 0.68A 5dzk3-2i5bA:
undetectable
5dzkm-2i5bA:
1.9		 5dzk3-2i5bA:
1.35
5dzkm-2i5bA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 5 ILE A  62
GLY A  11
ILE A  88
LEU A  38
 None
 0.66A 5dzkB-2i5bA:
3.1
5dzkI-2i5bA:
undetectable
5dzkW-2i5bA:
undetectable		 5dzkB-2i5bA:
23.16
5dzkI-2i5bA:
21.69
5dzkW-2i5bA:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 5 ILE A  62
GLY A  11
ILE A  88
LEU A  38
 None
 0.66A 5dzki-2i5bA:
undetectable
5dzkj-2i5bA:
1.9
5dzkx-2i5bA:
undetectable		 5dzki-2i5bA:
21.69
5dzkj-2i5bA:
21.69
5dzkx-2i5bA:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 5 ILE A  62
GLY A  11
ILE A  88
LEU A  38
 None
 0.74A 5dzkd-2i5bA:
3.1
5dzkk-2i5bA:
1.8
5dzky-2i5bA:
undetectable		 5dzkd-2i5bA:
23.16
5dzkk-2i5bA:
21.69
5dzky-2i5bA:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 4 ILE A  62
GLY A  11
ILE A  88
LEU A  38
 None
 0.71A 5dzkl-2i5bA:
1.9
5dzkz-2i5bA:
undetectable		 5dzkl-2i5bA:
21.69
5dzkz-2i5bA:
1.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eeuB-2i5bA:
undetectable
5eeuC-2i5bA:
undetectable		 5eeuB-2i5bA:
18.03
5eeuC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeuC-2i5bA:
undetectable
5eeuD-2i5bA:
undetectable		 5eeuC-2i5bA:
18.03
5eeuD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eeuE-2i5bA:
undetectable
5eeuF-2i5bA:
undetectable		 5eeuE-2i5bA:
18.03
5eeuF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeuG-2i5bA:
undetectable
5eeuH-2i5bA:
undetectable		 5eeuG-2i5bA:
18.03
5eeuH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeuH-2i5bA:
undetectable
5eeuI-2i5bA:
undetectable		 5eeuH-2i5bA:
18.03
5eeuI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eeuJ-2i5bA:
undetectable
5eeuK-2i5bA:
undetectable		 5eeuJ-2i5bA:
18.03
5eeuK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeuA-2i5bA:
undetectable
5eeuK-2i5bA:
undetectable		 5eeuA-2i5bA:
18.03
5eeuK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeuN-2i5bA:
undetectable
5eeuO-2i5bA:
undetectable		 5eeuN-2i5bA:
18.03
5eeuO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeuR-2i5bA:
undetectable
5eeuS-2i5bA:
undetectable		 5eeuR-2i5bA:
18.03
5eeuS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeuS-2i5bA:
undetectable
5eeuT-2i5bA:
undetectable		 5eeuS-2i5bA:
18.03
5eeuT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeuT-2i5bA:
undetectable
5eeuU-2i5bA:
undetectable		 5eeuT-2i5bA:
18.03
5eeuU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeuU-2i5bA:
undetectable
5eeuV-2i5bA:
undetectable		 5eeuU-2i5bA:
18.03
5eeuV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eevB-2i5bA:
undetectable
5eevC-2i5bA:
undetectable		 5eevB-2i5bA:
18.03
5eevC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eevC-2i5bA:
undetectable
5eevD-2i5bA:
undetectable		 5eevC-2i5bA:
18.03
5eevD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eevE-2i5bA:
undetectable
5eevF-2i5bA:
undetectable		 5eevE-2i5bA:
18.03
5eevF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eevG-2i5bA:
undetectable
5eevH-2i5bA:
undetectable		 5eevG-2i5bA:
18.03
5eevH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eevH-2i5bA:
undetectable
5eevI-2i5bA:
undetectable		 5eevH-2i5bA:
18.03
5eevI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eevJ-2i5bA:
undetectable
5eevK-2i5bA:
undetectable		 5eevJ-2i5bA:
18.03
5eevK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eevA-2i5bA:
undetectable
5eevK-2i5bA:
undetectable		 5eevA-2i5bA:
18.03
5eevK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eevN-2i5bA:
undetectable
5eevO-2i5bA:
undetectable		 5eevN-2i5bA:
18.03
5eevO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.32A 5eevR-2i5bA:
undetectable
5eevS-2i5bA:
undetectable		 5eevR-2i5bA:
18.03
5eevS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eevS-2i5bA:
undetectable
5eevT-2i5bA:
undetectable		 5eevS-2i5bA:
18.03
5eevT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eevT-2i5bA:
undetectable
5eevU-2i5bA:
undetectable		 5eevT-2i5bA:
18.03
5eevU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eevU-2i5bA:
undetectable
5eevV-2i5bA:
undetectable		 5eevU-2i5bA:
18.03
5eevV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eewB-2i5bA:
undetectable
5eewC-2i5bA:
undetectable		 5eewB-2i5bA:
18.03
5eewC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eewC-2i5bA:
undetectable
5eewD-2i5bA:
undetectable		 5eewC-2i5bA:
18.03
5eewD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eewE-2i5bA:
undetectable
5eewF-2i5bA:
undetectable		 5eewE-2i5bA:
18.03
5eewF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eewG-2i5bA:
undetectable
5eewH-2i5bA:
undetectable		 5eewG-2i5bA:
18.03
5eewH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eewH-2i5bA:
undetectable
5eewI-2i5bA:
undetectable		 5eewH-2i5bA:
18.03
5eewI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eewJ-2i5bA:
undetectable
5eewK-2i5bA:
undetectable		 5eewJ-2i5bA:
18.03
5eewK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eewA-2i5bA:
undetectable
5eewK-2i5bA:
undetectable		 5eewA-2i5bA:
18.03
5eewK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eewN-2i5bA:
undetectable
5eewO-2i5bA:
undetectable		 5eewN-2i5bA:
18.03
5eewO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eewR-2i5bA:
undetectable
5eewS-2i5bA:
undetectable		 5eewR-2i5bA:
18.03
5eewS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eewS-2i5bA:
undetectable
5eewT-2i5bA:
undetectable		 5eewS-2i5bA:
18.03
5eewT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eewT-2i5bA:
undetectable
5eewU-2i5bA:
undetectable		 5eewT-2i5bA:
18.03
5eewU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eewU-2i5bA:
undetectable
5eewV-2i5bA:
undetectable		 5eewU-2i5bA:
18.03
5eewV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eexB-2i5bA:
undetectable
5eexC-2i5bA:
undetectable		 5eexB-2i5bA:
18.03
5eexC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eexC-2i5bA:
undetectable
5eexD-2i5bA:
undetectable		 5eexC-2i5bA:
18.03
5eexD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eexE-2i5bA:
undetectable
5eexF-2i5bA:
undetectable		 5eexE-2i5bA:
18.03
5eexF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eexG-2i5bA:
undetectable
5eexH-2i5bA:
undetectable		 5eexG-2i5bA:
18.03
5eexH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eexH-2i5bA:
undetectable
5eexI-2i5bA:
undetectable		 5eexH-2i5bA:
18.03
5eexI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eexI-2i5bA:
undetectable
5eexJ-2i5bA:
undetectable		 5eexI-2i5bA:
18.03
5eexJ-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eexJ-2i5bA:
undetectable
5eexK-2i5bA:
undetectable		 5eexJ-2i5bA:
18.03
5eexK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eexA-2i5bA:
undetectable
5eexK-2i5bA:
undetectable		 5eexA-2i5bA:
18.03
5eexK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eexN-2i5bA:
undetectable
5eexO-2i5bA:
undetectable		 5eexN-2i5bA:
18.03
5eexO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eexQ-2i5bA:
undetectable
5eexR-2i5bA:
undetectable		 5eexQ-2i5bA:
18.03
5eexR-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eexR-2i5bA:
undetectable
5eexS-2i5bA:
undetectable		 5eexR-2i5bA:
18.03
5eexS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eexS-2i5bA:
undetectable
5eexT-2i5bA:
undetectable		 5eexS-2i5bA:
18.03
5eexT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eexT-2i5bA:
undetectable
5eexU-2i5bA:
undetectable		 5eexT-2i5bA:
18.03
5eexU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eexU-2i5bA:
undetectable
5eexV-2i5bA:
undetectable		 5eexU-2i5bA:
18.03
5eexV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeyB-2i5bA:
undetectable
5eeyC-2i5bA:
undetectable		 5eeyB-2i5bA:
18.03
5eeyC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeyC-2i5bA:
undetectable
5eeyD-2i5bA:
undetectable		 5eeyC-2i5bA:
18.03
5eeyD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eeyE-2i5bA:
undetectable
5eeyF-2i5bA:
undetectable		 5eeyE-2i5bA:
18.03
5eeyF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeyG-2i5bA:
undetectable
5eeyH-2i5bA:
undetectable		 5eeyG-2i5bA:
18.03
5eeyH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeyH-2i5bA:
undetectable
5eeyI-2i5bA:
undetectable		 5eeyH-2i5bA:
18.03
5eeyI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeyI-2i5bA:
undetectable
5eeyJ-2i5bA:
undetectable		 5eeyI-2i5bA:
18.03
5eeyJ-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eeyJ-2i5bA:
undetectable
5eeyK-2i5bA:
undetectable		 5eeyJ-2i5bA:
18.03
5eeyK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeyA-2i5bA:
undetectable
5eeyK-2i5bA:
undetectable		 5eeyA-2i5bA:
18.03
5eeyK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeyN-2i5bA:
undetectable
5eeyO-2i5bA:
undetectable		 5eeyN-2i5bA:
18.03
5eeyO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eeyQ-2i5bA:
undetectable
5eeyR-2i5bA:
undetectable		 5eeyQ-2i5bA:
18.03
5eeyR-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeyR-2i5bA:
undetectable
5eeyS-2i5bA:
undetectable		 5eeyR-2i5bA:
18.03
5eeyS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeyS-2i5bA:
undetectable
5eeyT-2i5bA:
undetectable		 5eeyS-2i5bA:
18.03
5eeyT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eeyT-2i5bA:
undetectable
5eeyU-2i5bA:
undetectable		 5eeyT-2i5bA:
18.03
5eeyU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eeyU-2i5bA:
undetectable
5eeyV-2i5bA:
undetectable		 5eeyU-2i5bA:
18.03
5eeyV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eezB-2i5bA:
undetectable
5eezC-2i5bA:
undetectable		 5eezB-2i5bA:
18.03
5eezC-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eezC-2i5bA:
undetectable
5eezD-2i5bA:
undetectable		 5eezC-2i5bA:
18.03
5eezD-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5eezE-2i5bA:
undetectable
5eezF-2i5bA:
undetectable		 5eezE-2i5bA:
18.03
5eezF-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eezG-2i5bA:
undetectable
5eezH-2i5bA:
undetectable		 5eezG-2i5bA:
18.03
5eezH-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eezH-2i5bA:
undetectable
5eezI-2i5bA:
undetectable		 5eezH-2i5bA:
18.03
5eezI-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eezI-2i5bA:
undetectable
5eezJ-2i5bA:
undetectable		 5eezI-2i5bA:
18.03
5eezJ-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5eezJ-2i5bA:
undetectable
5eezK-2i5bA:
undetectable		 5eezJ-2i5bA:
18.03
5eezK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eezA-2i5bA:
undetectable
5eezK-2i5bA:
undetectable		 5eezA-2i5bA:
18.03
5eezK-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eezN-2i5bA:
undetectable
5eezO-2i5bA:
undetectable		 5eezN-2i5bA:
18.03
5eezO-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5eezQ-2i5bA:
undetectable
5eezR-2i5bA:
undetectable		 5eezQ-2i5bA:
18.03
5eezR-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eezR-2i5bA:
undetectable
5eezS-2i5bA:
undetectable		 5eezR-2i5bA:
18.03
5eezS-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eezS-2i5bA:
undetectable
5eezT-2i5bA:
undetectable		 5eezS-2i5bA:
18.03
5eezT-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5eezT-2i5bA:
undetectable
5eezU-2i5bA:
undetectable		 5eezT-2i5bA:
18.03
5eezU-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5eezU-2i5bA:
undetectable
5eezV-2i5bA:
undetectable		 5eezU-2i5bA:
18.03
5eezV-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef0B-2i5bA:
undetectable
5ef0C-2i5bA:
undetectable		 5ef0B-2i5bA:
18.03
5ef0C-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef0C-2i5bA:
undetectable
5ef0D-2i5bA:
undetectable		 5ef0C-2i5bA:
18.03
5ef0D-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef0E-2i5bA:
undetectable
5ef0F-2i5bA:
undetectable		 5ef0E-2i5bA:
18.03
5ef0F-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef0G-2i5bA:
undetectable
5ef0H-2i5bA:
undetectable		 5ef0G-2i5bA:
18.03
5ef0H-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef0H-2i5bA:
undetectable
5ef0I-2i5bA:
undetectable		 5ef0H-2i5bA:
18.03
5ef0I-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef0I-2i5bA:
undetectable
5ef0J-2i5bA:
undetectable		 5ef0I-2i5bA:
18.03
5ef0J-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5ef0J-2i5bA:
undetectable
5ef0K-2i5bA:
undetectable		 5ef0J-2i5bA:
18.03
5ef0K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef0A-2i5bA:
undetectable
5ef0K-2i5bA:
undetectable		 5ef0A-2i5bA:
18.03
5ef0K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef0N-2i5bA:
undetectable
5ef0O-2i5bA:
undetectable		 5ef0N-2i5bA:
18.03
5ef0O-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef0Q-2i5bA:
undetectable
5ef0R-2i5bA:
undetectable		 5ef0Q-2i5bA:
18.03
5ef0R-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.32A 5ef0R-2i5bA:
undetectable
5ef0S-2i5bA:
undetectable		 5ef0R-2i5bA:
18.03
5ef0S-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef0S-2i5bA:
undetectable
5ef0T-2i5bA:
undetectable		 5ef0S-2i5bA:
18.03
5ef0T-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef0T-2i5bA:
undetectable
5ef0U-2i5bA:
undetectable		 5ef0T-2i5bA:
18.03
5ef0U-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef0U-2i5bA:
undetectable
5ef0V-2i5bA:
undetectable		 5ef0U-2i5bA:
18.03
5ef0V-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef1B-2i5bA:
undetectable
5ef1C-2i5bA:
undetectable		 5ef1B-2i5bA:
18.03
5ef1C-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef1C-2i5bA:
undetectable
5ef1D-2i5bA:
undetectable		 5ef1C-2i5bA:
18.03
5ef1D-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef1E-2i5bA:
undetectable
5ef1F-2i5bA:
undetectable		 5ef1E-2i5bA:
18.03
5ef1F-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef1G-2i5bA:
undetectable
5ef1H-2i5bA:
undetectable		 5ef1G-2i5bA:
18.03
5ef1H-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef1H-2i5bA:
undetectable
5ef1I-2i5bA:
undetectable		 5ef1H-2i5bA:
18.03
5ef1I-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef1I-2i5bA:
undetectable
5ef1J-2i5bA:
undetectable		 5ef1I-2i5bA:
18.03
5ef1J-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5ef1J-2i5bA:
undetectable
5ef1K-2i5bA:
undetectable		 5ef1J-2i5bA:
18.03
5ef1K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef1A-2i5bA:
undetectable
5ef1K-2i5bA:
undetectable		 5ef1A-2i5bA:
18.03
5ef1K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef1N-2i5bA:
undetectable
5ef1O-2i5bA:
undetectable		 5ef1N-2i5bA:
18.03
5ef1O-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef1Q-2i5bA:
undetectable
5ef1R-2i5bA:
undetectable		 5ef1Q-2i5bA:
18.03
5ef1R-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef1R-2i5bA:
undetectable
5ef1S-2i5bA:
undetectable		 5ef1R-2i5bA:
18.03
5ef1S-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef1S-2i5bA:
undetectable
5ef1T-2i5bA:
undetectable		 5ef1S-2i5bA:
18.03
5ef1T-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef1T-2i5bA:
undetectable
5ef1U-2i5bA:
undetectable		 5ef1T-2i5bA:
18.03
5ef1U-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef1U-2i5bA:
undetectable
5ef1V-2i5bA:
undetectable		 5ef1U-2i5bA:
18.03
5ef1V-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef2B-2i5bA:
undetectable
5ef2C-2i5bA:
undetectable		 5ef2B-2i5bA:
18.03
5ef2C-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef2C-2i5bA:
undetectable
5ef2D-2i5bA:
undetectable		 5ef2C-2i5bA:
18.03
5ef2D-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef2E-2i5bA:
undetectable
5ef2F-2i5bA:
undetectable		 5ef2E-2i5bA:
18.03
5ef2F-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef2G-2i5bA:
undetectable
5ef2H-2i5bA:
undetectable		 5ef2G-2i5bA:
18.03
5ef2H-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef2H-2i5bA:
undetectable
5ef2I-2i5bA:
undetectable		 5ef2H-2i5bA:
18.03
5ef2I-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef2I-2i5bA:
undetectable
5ef2J-2i5bA:
undetectable		 5ef2I-2i5bA:
18.03
5ef2J-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5ef2J-2i5bA:
undetectable
5ef2K-2i5bA:
undetectable		 5ef2J-2i5bA:
18.03
5ef2K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef2A-2i5bA:
undetectable
5ef2K-2i5bA:
undetectable		 5ef2A-2i5bA:
18.03
5ef2K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef2N-2i5bA:
undetectable
5ef2O-2i5bA:
undetectable		 5ef2N-2i5bA:
18.03
5ef2O-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef2Q-2i5bA:
undetectable
5ef2R-2i5bA:
undetectable		 5ef2Q-2i5bA:
18.03
5ef2R-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef2R-2i5bA:
undetectable
5ef2S-2i5bA:
undetectable		 5ef2R-2i5bA:
18.03
5ef2S-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef2S-2i5bA:
undetectable
5ef2T-2i5bA:
undetectable		 5ef2S-2i5bA:
18.03
5ef2T-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef2T-2i5bA:
undetectable
5ef2U-2i5bA:
undetectable		 5ef2T-2i5bA:
18.03
5ef2U-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef2U-2i5bA:
undetectable
5ef2V-2i5bA:
undetectable		 5ef2U-2i5bA:
18.03
5ef2V-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef3B-2i5bA:
undetectable
5ef3C-2i5bA:
undetectable		 5ef3B-2i5bA:
18.03
5ef3C-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef3C-2i5bA:
undetectable
5ef3D-2i5bA:
undetectable		 5ef3C-2i5bA:
18.03
5ef3D-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.29A 5ef3E-2i5bA:
undetectable
5ef3F-2i5bA:
undetectable		 5ef3E-2i5bA:
18.03
5ef3F-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef3G-2i5bA:
undetectable
5ef3H-2i5bA:
undetectable		 5ef3G-2i5bA:
18.03
5ef3H-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef3H-2i5bA:
undetectable
5ef3I-2i5bA:
undetectable		 5ef3H-2i5bA:
18.03
5ef3I-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 11 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef3I-2i5bA:
undetectable
5ef3J-2i5bA:
undetectable		 5ef3I-2i5bA:
18.03
5ef3J-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.27A 5ef3J-2i5bA:
undetectable
5ef3K-2i5bA:
undetectable		 5ef3J-2i5bA:
18.03
5ef3K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef3A-2i5bA:
undetectable
5ef3K-2i5bA:
undetectable		 5ef3A-2i5bA:
18.03
5ef3K-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef3N-2i5bA:
undetectable
5ef3O-2i5bA:
undetectable		 5ef3N-2i5bA:
18.03
5ef3O-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 9 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.28A 5ef3Q-2i5bA:
undetectable
5ef3R-2i5bA:
undetectable		 5ef3Q-2i5bA:
18.03
5ef3R-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef3R-2i5bA:
undetectable
5ef3S-2i5bA:
undetectable		 5ef3R-2i5bA:
18.03
5ef3S-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef3S-2i5bA:
undetectable
5ef3T-2i5bA:
undetectable		 5ef3S-2i5bA:
18.03
5ef3T-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.30A 5ef3T-2i5bA:
undetectable
5ef3U-2i5bA:
undetectable		 5ef3T-2i5bA:
18.03
5ef3U-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 10 GLY A 215
ALA A 239
THR A  26
THR A 217
ILE A 243
 ADP  A 301 (-3.2A)
None
None
None
ADP  A 301 (-4.1A)
 1.31A 5ef3U-2i5bA:
undetectable
5ef3V-2i5bA:
undetectable		 5ef3U-2i5bA:
18.03
5ef3V-2i5bA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 8 ILE A  88
VAL A 222
ILE A 236
ILE A 138
ASP A 107
 None
 1.45A 5hi2A-2i5bA:
undetectable		 5hi2A-2i5bA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 THR A 178
GLY A 180
ALA A 214
GLY A 215
ILE A 247
 ADP  A 301 (-3.5A)
ADP  A 301 (-3.5A)
ADP  A 301 (-3.6A)
ADP  A 301 (-3.2A)
ADP  A 301 (-4.3A)
 0.79A 5kb6A-2i5bA:
18.8		 5kb6A-2i5bA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		5 / 12 THR A 178
GLY A 180
ALA A 214
GLY A 215
ILE A 247
 ADP  A 301 (-3.5A)
ADP  A 301 (-3.5A)
ADP  A 301 (-3.6A)
ADP  A 301 (-3.2A)
ADP  A 301 (-4.3A)
 0.80A 5kb6B-2i5bA:
19.0		 5kb6B-2i5bA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2i5b PHOSPHOMETHYLPYRIMID
INE KINASE
(Bacillus
subtilis) 		4 / 7 ALA A  67
ILE A  88
LEU A  91
ILE A  20
 None
 0.89A 6b5vA-2i5bA:
undetectable
6b5vB-2i5bA:
undetectable		 6b5vA-2i5bA:
13.60
6b5vB-2i5bA:
13.60