SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		6 / 7 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
TYR O 317
 None
 0.24A 1dssG-2i5pO:
44.2		 1dssG-2i5pO:
63.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		6 / 7 SER O 148
THR O 150
CYH O 153
TYR O 311
ASN O 313
TYR O 317
 None
 0.74A 1dssG-2i5pO:
44.2		 1dssG-2i5pO:
63.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		6 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
TYR O 317
 None
 0.27A 1dssR-2i5pO:
44.0		 1dssR-2i5pO:
63.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 8 SER O 148
THR O 150
TYR O 311
ASN O 313
TYR O 317
 None
 0.82A 1dssR-2i5pO:
44.0		 1dssR-2i5pO:
63.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 11 PHE O  44
ILE O  30
GLY O   7
PHE O   8
ALA O  92
 None
 1.33A 1ju6A-2i5pO:
undetectable		 1ju6A-2i5pO:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 8 ILE O 161
LEU O 307
ILE O 157
VAL O 259
ILE O 160
 None
 1.42A 1linA-2i5pO:
undetectable		 1linA-2i5pO:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 12 LEU O  16
ILE O  25
SER O   2
ILE O   3
ALA O   4
 None
 1.02A 2bxqA-2i5pO:
undetectable		 2bxqA-2i5pO:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 9 VAL O 130
GLY O 131
PRO O 156
THR O 290
GLY O 272
 None
 1.36A 3bjwG-2i5pO:
0.5		 3bjwG-2i5pO:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 12 GLY O 131
SER O 289
THR O 290
VAL O 262
ALA O 155
 None
 1.14A 3d91B-2i5pO:
undetectable		 3d91B-2i5pO:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		6 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
TYR O 317
 None
 0.29A 3dmtC-2i5pO:
41.8		 3dmtC-2i5pO:
51.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 8 SER O 148
THR O 150
TYR O 311
ASN O 313
TYR O 317
 None
 0.81A 3dmtC-2i5pO:
41.8		 3dmtC-2i5pO:
51.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		4 / 6 THR O  96
ASN O   6
ASP O  32
ILE O  34
 None
 1.23A 3w9tB-2i5pO:
undetectable		 3w9tB-2i5pO:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		4 / 6 ILE O 161
VAL O 262
PHE O 292
THR O 290
 None
 1.05A 4xe5A-2i5pO:
4.7		 4xe5A-2i5pO:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 8 LEU O 221
GLY O 215
VAL O 214
ALA O 158
GLY O 170
 None
 1.14A 4zauA-2i5pO:
undetectable		 4zauA-2i5pO:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 8 LEU O 225
GLY O 215
VAL O 214
LEU O 242
GLY O 227
 None
 1.19A 4zauA-2i5pO:
undetectable		 4zauA-2i5pO:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		3 / 3 THR O 151
ALA O 147
ASN O 152
 None
 0.55A 5ersA-2i5pO:
2.3		 5ersA-2i5pO:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		4 / 6 PHE O 230
VAL O 175
ALA O 229
THR O 150
 None
None
BME  O1023 ( 4.8A)
None
 1.10A 5t7bA-2i5pO:
3.5		 5t7bA-2i5pO:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		4 / 6 ASN O 313
TYR O 311
VAL O 175
THR O 174
 None
 1.33A 6f32B-2i5pO:
2.5		 6f32B-2i5pO:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1
(Kluyveromyces
marxianus) 		5 / 11 PHE O  44
ILE O  30
LEU O  82
GLY O   7
PHE O   8
 None
 1.32A 6r2eG-2i5pO:
undetectable		 6r2eG-2i5pO:
25.53