SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 PHE A  92
LEU A  37
MET A 105
 None
 0.62A 1mx1D-2i6gA:
undetectable		 1mx1D-2i6gA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  37
GLY A  38
GLY A  40
LEU A  87
LEU A  90
 None
 0.90A 2zbpA-2i6gA:
15.4		 2zbpA-2i6gA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A  38
GLY A  40
ASP A  86
LEU A  87
ASN A  88
 None
 0.84A 2zw9B-2i6gA:
12.3		 2zw9B-2i6gA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  37
GLY A  38
GLY A  40
LEU A  87
LEU A  90
 None
 0.81A 3cjtG-2i6gA:
15.2		 3cjtG-2i6gA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  37
GLY A  38
GLY A  40
LEU A  87
LEU A  90
 None
 0.82A 3cjtO-2i6gA:
15.3		 3cjtO-2i6gA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  23
ALA A  25
LEU A 100
LEU A 131
LEU A  48
 None
MLY  A 167 ( 4.2A)
None
None
None
 1.20A 3erdA-2i6gA:
undetectable		 3erdA-2i6gA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  23
ALA A  25
LEU A 100
LEU A 131
LEU A  48
 None
MLY  A 167 ( 4.2A)
None
None
None
 1.16A 3hm1A-2i6gA:
undetectable		 3hm1A-2i6gA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 11 LEU A  23
ALA A  25
LEU A 100
LEU A 131
LEU A  48
 None
MLY  A 167 ( 4.2A)
None
None
None
 1.18A 4zn7B-2i6gA:
undetectable		 4zn7B-2i6gA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2i6g PUTATIVE
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 ASN A  79
VAL A  55
ALA A  57
GLY A  42
 EDO  A 205 (-3.4A)
None
None
EDO  A 200 ( 4.8A)
 0.86A 5fpdB-2i6gA:
undetectable		 5fpdB-2i6gA:
20.00