SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i6h HYPOTHETICAL PROTEIN
ATU0120
(Agrobacterium
fabrum) 		5 / 11 TYR A 114
ALA A  58
GLY A  57
ARG A 128
PHE A 117
 None
 1.34A 1l5rA-2i6hA:
undetectable		 1l5rA-2i6hA:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 2i6h HYPOTHETICAL PROTEIN
ATU0120
(Agrobacterium
fabrum) 		4 / 5 ILE A  12
LEU A  66
ALA A   9
PHE A 113
 None
 0.80A 2opxA-2i6hA:
undetectable		 2opxA-2i6hA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2i6h HYPOTHETICAL PROTEIN
ATU0120
(Agrobacterium
fabrum) 		5 / 11 PHE A  15
PHE A  31
GLY A  20
LEU A  66
PHE A  35
 None
 1.13A 3t3rA-2i6hA:
undetectable		 3t3rA-2i6hA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 2i6h HYPOTHETICAL PROTEIN
ATU0120
(Agrobacterium
fabrum) 		3 / 3 LEU A 109
VAL A  13
ASP A  14
 None
 0.60A 5x23A-2i6hA:
undetectable		 5x23A-2i6hA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2i6h HYPOTHETICAL PROTEIN
ATU0120
(Agrobacterium
fabrum) 		3 / 3 GLU A 121
ASP A  86
PRO A  87
 None
 0.52A 6berA-2i6hA:
undetectable		 6berA-2i6hA:
7.26