SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 12 PHE A  45
LEU A  36
ALA A  37
LEU A  42
ILE A 323
 None
 1.12A 1crbA-2i7gA:
undetectable		 1crbA-2i7gA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.96A 1l5qA-2i7gA:
undetectable		 1l5qA-2i7gA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 1.01A 1l5qB-2i7gA:
undetectable		 1l5qB-2i7gA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 1.00A 1l7xA-2i7gA:
undetectable		 1l7xA-2i7gA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 1.00A 1l7xB-2i7gA:
1.1		 1l7xB-2i7gA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		3 / 3 ILE A 233
ILE A 200
THR A 231
 None
 0.65A 1rg7A-2i7gA:
undetectable		 1rg7A-2i7gA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 8 ALA A 197
ASN A 234
GLY A 180
GLY A 113
 None
None
SO4  A 702 (-2.7A)
PEG  A 704 (-3.0A)
 0.82A 1rukH-2i7gA:
undetectable
1rukL-2i7gA:
undetectable		 1rukH-2i7gA:
20.00
1rukL-2i7gA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TD2_A_PXLA288_1
(PYRIDOXAMINE KINASE)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 10 ALA A 273
HIS A 274
THR A 270
TYR A 251
ASP A 276
 None
 1.23A 1td2A-2i7gA:
2.1		 1td2A-2i7gA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 6 PHE A 304
ILE A 200
PHE A 212
GLY A 181
GLY A 180
 None
None
None
None
SO4  A 702 (-2.7A)
 1.35A 2qx6A-2i7gA:
undetectable
2qx6B-2i7gA:
undetectable		 2qx6A-2i7gA:
19.95
2qx6B-2i7gA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		3 / 3 ARG A  52
GLU A 256
SER A 114
 None
 0.92A 2xkkA-2i7gA:
undetectable
2xkkC-2i7gA:
undetectable		 2xkkA-2i7gA:
19.33
2xkkC-2i7gA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 8 ALA A  67
PHE A  45
ILE A  74
THR A  71
 None
 0.86A 3bpxA-2i7gA:
undetectable
3bpxB-2i7gA:
undetectable		 3bpxA-2i7gA:
16.80
3bpxB-2i7gA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 1.00A 3dd1A-2i7gA:
2.5		 3dd1A-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.99A 3dd1B-2i7gA:
0.1		 3dd1B-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.97A 3ddsA-2i7gA:
0.6		 3ddsA-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.99A 3ddsB-2i7gA:
undetectable		 3ddsB-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.99A 3ddwA-2i7gA:
undetectable		 3ddwA-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 0.98A 3ddwB-2i7gA:
undetectable		 3ddwB-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 4 ILE A 233
PHE A 304
ILE A 200
THR A 231
 None
 0.96A 3ia4A-2i7gA:
undetectable		 3ia4A-2i7gA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 5 GLU A  49
GLY A  48
TYR A  55
ASP A  10
 None
 1.15A 3w9tD-2i7gA:
undetectable		 3w9tD-2i7gA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 316
ASN A  12
ARG A  52
VAL A 257
ILE A 261
 None
 0.94A 4aztA-2i7gA:
undetectable		 4aztA-2i7gA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 316
ASN A  12
ARG A  52
VAL A 257
ILE A 261
 None
 0.94A 4azvA-2i7gA:
undetectable		 4azvA-2i7gA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 12 LEU A  47
ILE A  34
LEU A  31
ALA A  65
LEU A  64
 None
 1.11A 4o1zB-2i7gA:
undetectable		 4o1zB-2i7gA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		3 / 3 GLU A 295
TYR A 205
GLU A 282
 None
 0.76A 4ryaA-2i7gA:
undetectable		 4ryaA-2i7gA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		3 / 3 MET A 324
GLN A 312
TYR A   6
 None
 0.98A 4udcA-2i7gA:
undetectable		 4udcA-2i7gA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A   4
LEU A 310
GLN A 170
GLY A  46
LEU A  42
 None
 0.88A 5hg0A-2i7gA:
undetectable		 5hg0A-2i7gA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 10 PHE A  45
ILE A 315
ASP A  10
VAL A  57
LEU A  30
 None
 1.42A 5jl7A-2i7gA:
0.0		 5jl7A-2i7gA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 5 TYR A 330
ILE A 327
LEU A 287
GLY A 237
PHE A 238
 None
 1.43A 5kmdC-2i7gA:
undetectable
5kmdD-2i7gA:
undetectable		 5kmdC-2i7gA:
20.93
5kmdD-2i7gA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		5 / 10 GLY A 181
GLY A 180
PHE A 304
ILE A 200
PHE A 212
 None
SO4  A 702 (-2.7A)
None
None
None
 1.29A 5lbtA-2i7gA:
undetectable
5lbtB-2i7gA:
undetectable		 5lbtA-2i7gA:
20.72
5lbtB-2i7gA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 4 LEU A 211
LEU A 214
SER A 185
ALA A 187
 None
None
SO4  A 702 (-2.7A)
None
 0.88A 5uunA-2i7gA:
undetectable		 5uunA-2i7gA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 7 GLY A 283
GLN A 312
TYR A   6
ASP A 276
 None
 0.97A 5vlmE-2i7gA:
undetectable		 5vlmE-2i7gA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 6 HIS A 156
VAL A  91
LEU A 143
GLN A  94
 None
 1.40A 5xdhA-2i7gA:
0.0
5xdhC-2i7gA:
0.0		 5xdhA-2i7gA:
11.73
5xdhC-2i7gA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 2i7g MONOOXYGENASE
(Agrobacterium
fabrum) 		4 / 7 LEU A  47
ALA A  66
ALA A  67
THR A  71
 None
 0.81A 6a7jA-2i7gA:
undetectable		 6a7jA-2i7gA:
14.51