SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LH8_A_VIBA1_1 (MAJOR PRION PROTEIN)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 6	PRO A 41 HIS A 43 ASP A 100 ASP A 109	None	0.98A	2lh8A-2i7hA: undetectable	2lh8A-2i7hA: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 8	ARG A 75 LEU A 62 ILE A 148 PHE A 144	None	0.93A	3ln1A-2i7hA: undetectable	3ln1A-2i7hA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 7	ARG A 75 LEU A 62 ILE A 148 PHE A 144	None	0.93A	3ln1B-2i7hA: undetectable	3ln1B-2i7hA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3POC_B_ACRB665_1 (ALPHA-GLUCOSIDASE)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 6	GLU A 99 ASP A 109 TYR A 110 ASP A 107	None	1.29A	3pocB-2i7hA: undetectable	3pocB-2i7hA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 5	LEU A 129 GLY A 163 THR A 89 ILE A 55	None	0.89A	3wriA-2i7hA: undetectable	3wriA-2i7hA: 20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 5	LEU A 129 GLY A 163 THR A 89 ILE A 55	None	0.90A	3wriB-2i7hA: undetectable	3wriB-2i7hA: 20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_C_STRC601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 5	ILE A 162 ARG A 127 ASP A 36 VAL A 95	None	0.99A	4nkxC-2i7hA: undetectable	4nkxC-2i7hA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_D_STRD601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2i7h	NITROREDUCTASE-LIKE FAMILY PROTEIN (Bacillus cereus)	4 / 5	ILE A 162 ARG A 127 ASP A 36 VAL A 95	None	0.97A	4nkxD-2i7hA: undetectable	4nkxD-2i7hA: 20.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2LH8_A_VIBA1_1","MAJOR PRION PROTEIN","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"PRO A  41;HIS A  43;ASP A 100;ASP A 109","None","0.98A","2lh8A-2i7hA:undetectable","2lh8A-2i7hA:17.18"],["3LN1_A_CELA682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"ARG A  75;LEU A  62;ILE A 148;PHE A 144","None","0.93A","3ln1A-2i7hA:undetectable","3ln1A-2i7hA:14.19"],["3LN1_B_CELB682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"ARG A  75;LEU A  62;ILE A 148;PHE A 144","None","0.93A","3ln1B-2i7hA:undetectable","3ln1B-2i7hA:14.19"],["3POC_B_ACRB665_1","ALPHA-GLUCOSIDASE","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"GLU A  99;ASP A 109;TYR A 110;ASP A 107","None","1.29A","3pocB-2i7hA:undetectable","3pocB-2i7hA:15.16"],["3WRI_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"LEU A 129;GLY A 163;THR A  89;ILE A  55","None","0.89A","3wriA-2i7hA:undetectable","3wriA-2i7hA:20.49"],["3WRI_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"LEU A 129;GLY A 163;THR A  89;ILE A  55","None","0.90A","3wriB-2i7hA:undetectable","3wriB-2i7hA:20.49"],["4NKX_C_STRC601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"ILE A 162;ARG A 127;ASP A  36;VAL A  95","None","0.99A","4nkxC-2i7hA:undetectable","4nkxC-2i7hA:20.27"],["4NKX_D_STRD601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2i7h","NITROREDUCTASE-LIKE FAMILY PROTEIN","Bacillus cereus",4,"ILE A 162;ARG A 127;ASP A  36;VAL A  95","None","0.97A","4nkxD-2i7hA:undetectable","4nkxD-2i7hA:20.27"]]