SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 11 LEU A 486
LEU A 492
ILE A 499
GLY A 502
LEU A 504
 None
 1.28A 1g50C-2i88A:
undetectable		 1g50C-2i88A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 5 THR A 490
GLY A 493
LYS A 362
TYR A 363
 None
 1.32A 1gtiF-2i88A:
undetectable		 1gtiF-2i88A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 7 ILE A 503
TRP A 495
LEU A 400
TRP A 460
 None
 1.39A 1q0yH-2i88A:
undetectable
1q0yL-2i88A:
undetectable		 1q0yH-2i88A:
19.05
1q0yL-2i88A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 12 ILE A 451
PHE A 393
LEU A 504
VAL A 500
LEU A 483
 None
 1.32A 2bxfB-2i88A:
2.1		 2bxfB-2i88A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 6 LEU A 452
LYS A 455
ARG A 409
GLY A 458
 None
 1.13A 2hs2B-2i88A:
undetectable		 2hs2B-2i88A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 11 VAL A 479
LEU A 482
ILE A 451
PRO A 462
THR A 466
 None
 1.24A 3bjwB-2i88A:
undetectable		 3bjwB-2i88A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 11 VAL A 479
LEU A 482
ILE A 451
PRO A 462
THR A 466
 None
 1.23A 3bjwE-2i88A:
undetectable		 3bjwE-2i88A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 12 VAL A 479
LEU A 482
ILE A 451
PRO A 462
THR A 466
 None
 1.24A 3bjwF-2i88A:
undetectable		 3bjwF-2i88A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2i88 COLICIN-E1
(Escherichia
coli) 		5 / 11 VAL A 479
LEU A 482
ILE A 451
PRO A 462
THR A 466
 None
 1.20A 3bjwH-2i88A:
undetectable		 3bjwH-2i88A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 8 LEU A 513
CYH A 505
TYR A 396
PHE A 393
 None
 1.27A 3po7A-2i88A:
undetectable		 3po7A-2i88A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 8 TRP A 460
VAL A 447
LEU A 486
ILE A 503
 None
 0.88A 3u5kA-2i88A:
undetectable		 3u5kA-2i88A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2i88 COLICIN-E1
(Escherichia
coli) 		4 / 8 TRP A 460
VAL A 447
LEU A 486
ILE A 503
 None
 0.89A 3u5kC-2i88A:
undetectable		 3u5kC-2i88A:
19.57