SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 204
ILE A  64
LEU A 202
HIS A 200
 None
 0.87A 2azxA-2i9dA:
undetectable		 2azxA-2i9dA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 205
LEU A  58
ALA A  61
PHE A  67
 None
 0.86A 2vcvL-2i9dA:
undetectable		 2vcvL-2i9dA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A   2
ARG A  76
LYS A 163
 None
 1.28A 3okxA-2i9dA:
undetectable		 3okxA-2i9dA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 135
LEU A 143
MET A  85
LEU A 171
 None
 1.19A 5dxeA-2i9dA:
undetectable		 5dxeA-2i9dA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 135
LEU A 143
MET A  85
LEU A 171
 None
 1.20A 6cbzA-2i9dA:
undetectable		 6cbzA-2i9dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2i9d CHLORAMPHENICOL
ACETYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  70
PHE A  19
PHE A  67
 None
 1.08A 6nknC-2i9dA:
undetectable
6nknJ-2i9dA:
undetectable		 6nknC-2i9dA:
19.19
6nknJ-2i9dA:
12.44