SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 12 GLU A 114
GLY A 117
VAL A 140
VAL A 120
ASN A 179
 None
 1.31A 1n2xA-2i9iA:
undetectable		 1n2xA-2i9iA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		4 / 6 ILE A  88
ARG A 122
ILE A 109
PHE A 178
 None
 1.15A 2q72A-2i9iA:
undetectable		 2q72A-2i9iA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 9 TYR A 241
LEU A 141
LEU A 252
ALA A 248
PHE A 178
 None
 1.25A 2vcvE-2i9iA:
undetectable		 2vcvE-2i9iA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 9 TYR A 241
LEU A 141
LEU A 252
ALA A 248
PHE A 178
 None
 1.26A 2vcvH-2i9iA:
undetectable		 2vcvH-2i9iA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 9 TYR A 241
LEU A 141
LEU A 252
ALA A 248
PHE A 178
 None
 1.24A 2vcvI-2i9iA:
undetectable		 2vcvI-2i9iA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 12 ASP A 231
ASP A 170
ILE A 233
ASP A  64
ARG A 239
 None
 1.30A 3iv6B-2i9iA:
undetectable		 3iv6B-2i9iA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 2i9i HYPOTHETICAL PROTEIN
(Helicobacter
pylori) 		5 / 12 GLN A 119
LEU A 121
ILE A 137
TYR A 181
PHE A 180
 None
 1.28A 5vlmB-2i9iA:
undetectable		 5vlmB-2i9iA:
21.46