SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  73
HIS A  75
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.64A 1a4lA-2i9uA:
21.7		 1a4lA-2i9uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  94
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.60A 1a4lB-2i9uA:
21.5		 1a4lB-2i9uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  73
HIS A  75
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.58A 1a4lC-2i9uA:
21.6		 1a4lC-2i9uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.48A 1a4lD-2i9uA:
21.4		 1a4lD-2i9uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 HIS A 229
HIS A  73
HIS A 269
HIS A  75
 GUN  A 503 ( 3.5A)
FE  A 501 (-3.4A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 3.6A)
 0.99A 1bzmA-2i9uA:
undetectable		 1bzmA-2i9uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 ILE A 153
ALA A 155
VAL A 130
VAL A 374
LEU A 386
 None
 1.11A 1n4hA-2i9uA:
undetectable		 1n4hA-2i9uA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 1nsiC-2i9uA:
0.8
1nsiD-2i9uA:
undetectable		 1nsiC-2i9uA:
21.31
1nsiD-2i9uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 10 VAL A 130
LEU A 122
LEU A 118
TYR A 115
ALA A  74
 None
 1.37A 1pbcA-2i9uA:
undetectable		 1pbcA-2i9uA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKW_A_PNTA225_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLU A 172
TYR A 254
SER A 228
THR A 200
TYR A 250
 None
 1.43A 1rkwA-2i9uA:
0.0		 1rkwA-2i9uA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 9 LEU A 122
LEU A 132
ALA A 323
LEU A  82
GLN A  78
 None
None
GUN  A 503 ( 4.1A)
None
GUN  A 503 (-3.4A)
 1.15A 1tbfA-2i9uA:
undetectable		 1tbfA-2i9uA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 GLU A 396
GLU A 402
LEU A 410
 None
 0.73A 1v8bA-2i9uA:
3.4		 1v8bA-2i9uA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 GLU A 396
GLU A 402
LEU A 410
 None
 0.72A 1v8bB-2i9uA:
3.4		 1v8bB-2i9uA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.07A 1ydbA-2i9uA:
undetectable		 1ydbA-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 10 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.06A 1yddA-2i9uA:
undetectable		 1yddA-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.03A 1zsbA-2i9uA:
undetectable		 1zsbA-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ALA A 385
PHE A 377
ILE A  41
VAL A  36
 None
 0.95A 2cizA-2i9uA:
undetectable		 2cizA-2i9uA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 LEU A 132
VAL A 157
GLY A 158
LEU A 118
THR A 141
 None
 1.03A 2egvA-2i9uA:
undetectable		 2egvA-2i9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 LEU A 132
VAL A 157
GLY A 158
LEU A 118
THR A 141
 None
 1.01A 2egvB-2i9uA:
undetectable		 2egvB-2i9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 LEU A  90
LEU A  94
ILE A 271
HIS A  73
VAL A 160
 GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
None
FE  A 501 (-3.4A)
None
 1.00A 2hrcB-2i9uA:
undetectable		 2hrcB-2i9uA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 2hx3A-2i9uA:
undetectable
2hx3B-2i9uA:
undetectable		 2hx3A-2i9uA:
20.97
2hx3B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 LEU A 298
HIS A  73
HIS A  75
HIS A 229
 None
FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
 0.93A 2ow9A-2i9uA:
undetectable		 2ow9A-2i9uA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  73
HIS A 229
GLU A 232
SER A 294
ASP A 320
 FE  A 501 (-3.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.3A)
FE  A 501 ( 2.7A)
 1.41A 2pgfA-2i9uA:
22.3		 2pgfA-2i9uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
HIS A 229
GLU A 232
HIS A 269
SER A 294
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
GUN  A 503 ( 4.3A)
FE  A 501 ( 2.7A)
 0.38A 2pgfA-2i9uA:
22.3		 2pgfA-2i9uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  73
HIS A  75
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.49A 2pgrA-2i9uA:
22.3		 2pgrA-2i9uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.12A 2pouA-2i9uA:
undetectable		 2pouA-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 MET A 362
ALA A 336
LEU A 329
GLN A 227
LEU A 266
 None
 1.36A 2rctA-2i9uA:
undetectable		 2rctA-2i9uA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 10 ASP A 139
SER A 151
ILE A 119
LEU A 136
ILE A 153
 None
 1.31A 2v0mA-2i9uA:
undetectable		 2v0mA-2i9uA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 TYR A 254
TYR A 250
CYH A 270
ILE A 281
 None
 1.35A 2xz5A-2i9uA:
0.0
2xz5B-2i9uA:
0.0		 2xz5A-2i9uA:
19.68
2xz5B-2i9uA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 TYR A 254
TYR A 250
CYH A 270
ILE A 281
 None
 1.34A 2xz5B-2i9uA:
undetectable
2xz5E-2i9uA:
undetectable		 2xz5B-2i9uA:
19.68
2xz5E-2i9uA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 ILE A 281
TYR A 254
TYR A 250
CYH A 270
 None
 1.28A 2xz5A-2i9uA:
undetectable
2xz5C-2i9uA:
undetectable		 2xz5A-2i9uA:
19.68
2xz5C-2i9uA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ILE A 281
TYR A 254
TYR A 250
CYH A 270
 None
 1.31A 2xz5D-2i9uA:
undetectable
2xz5E-2i9uA:
undetectable		 2xz5D-2i9uA:
19.68
2xz5E-2i9uA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 5 ALA A 323
GLY A 318
CYH A 291
HIS A 269
 GUN  A 503 ( 4.1A)
None
None
GUN  A 503 ( 4.4A)
 1.37A 2ylgA-2i9uA:
undetectable		 2ylgA-2i9uA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 THR A  20
PHE A 383
ARG A 129
ASN A  70
GLY A 367
 None
 1.44A 3aobC-2i9uA:
undetectable		 3aobC-2i9uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 LYS A 245
LYS A 241
PRO A 205
PHE A 203
 None
None
None
GUN  A 503 (-3.5A)
 1.50A 3bjwD-2i9uA:
undetectable		 3bjwD-2i9uA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.07A 3bl1A-2i9uA:
undetectable		 3bl1A-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.05A 3dc3A-2i9uA:
undetectable		 3dc3A-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 3e7gA-2i9uA:
0.6
3e7gB-2i9uA:
0.9		 3e7gA-2i9uA:
21.71
3e7gB-2i9uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.28A 3e7gA-2i9uA:
0.6
3e7gB-2i9uA:
0.9		 3e7gA-2i9uA:
21.71
3e7gB-2i9uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 3e7gC-2i9uA:
0.8
3e7gD-2i9uA:
0.7		 3e7gC-2i9uA:
21.71
3e7gD-2i9uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.27A 3e7gC-2i9uA:
undetectable
3e7gD-2i9uA:
undetectable		 3e7gC-2i9uA:
21.71
3e7gD-2i9uA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.08A 3hkuA-2i9uA:
undetectable		 3hkuA-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.05A 3hs4A-2i9uA:
undetectable		 3hs4A-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 3jwsA-2i9uA:
0.4
3jwsB-2i9uA:
undetectable		 3jwsA-2i9uA:
20.97
3jwsB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.33A 3jwtA-2i9uA:
0.4
3jwtB-2i9uA:
undetectable		 3jwtA-2i9uA:
20.97
3jwtB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 3jwtA-2i9uA:
0.3
3jwtB-2i9uA:
undetectable		 3jwtA-2i9uA:
20.97
3jwtB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 3jwuA-2i9uA:
undetectable
3jwuB-2i9uA:
0.4		 3jwuA-2i9uA:
20.97
3jwuB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 3jwuA-2i9uA:
undetectable
3jwuB-2i9uA:
0.4		 3jwuA-2i9uA:
20.97
3jwuB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 3jwvA-2i9uA:
undetectable
3jwvB-2i9uA:
undetectable		 3jwvA-2i9uA:
20.97
3jwvB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 3jwvA-2i9uA:
undetectable
3jwvB-2i9uA:
undetectable		 3jwvA-2i9uA:
20.97
3jwvB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.25A 3jx5A-2i9uA:
undetectable
3jx5B-2i9uA:
0.4		 3jx5A-2i9uA:
21.17
3jx5B-2i9uA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 5 LEU A 298
HIS A  73
HIS A  75
HIS A 229
 None
FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
 0.98A 3kecA-2i9uA:
undetectable		 3kecA-2i9uA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.11A 3ml5A-2i9uA:
undetectable		 3ml5A-2i9uA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.30A 3n5pA-2i9uA:
0.0
3n5pB-2i9uA:
0.0		 3n5pA-2i9uA:
20.80
3n5pB-2i9uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.34A 3nlkA-2i9uA:
undetectable
3nlkB-2i9uA:
0.4		 3nlkA-2i9uA:
20.97
3nlkB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 3nlkA-2i9uA:
undetectable
3nlkB-2i9uA:
0.4		 3nlkA-2i9uA:
20.97
3nlkB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 3nlnA-2i9uA:
undetectable
3nlnB-2i9uA:
undetectable		 3nlnA-2i9uA:
20.97
3nlnB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.32A 3nlnA-2i9uA:
undetectable
3nlnB-2i9uA:
undetectable		 3nlnA-2i9uA:
20.97
3nlnB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 3nloA-2i9uA:
undetectable
3nloB-2i9uA:
0.4		 3nloA-2i9uA:
20.97
3nloB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 3nloA-2i9uA:
undetectable
3nloB-2i9uA:
0.4		 3nloA-2i9uA:
20.97
3nloB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.25A 3nlpA-2i9uA:
undetectable
3nlpB-2i9uA:
0.3		 3nlpA-2i9uA:
21.17
3nlpB-2i9uA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 3nlrA-2i9uA:
undetectable
3nlrB-2i9uA:
0.4		 3nlrA-2i9uA:
21.17
3nlrB-2i9uA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 3nlyA-2i9uA:
undetectable
3nlyB-2i9uA:
0.4		 3nlyA-2i9uA:
20.97
3nlyB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 3nnyA-2i9uA:
undetectable
3nnyB-2i9uA:
undetectable		 3nnyA-2i9uA:
20.97
3nnyB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 3nnyA-2i9uA:
undetectable
3nnyB-2i9uA:
undetectable		 3nnyA-2i9uA:
20.97
3nnyB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.42A 3rqkA-2i9uA:
0.4
3rqkB-2i9uA:
0.4		 3rqkA-2i9uA:
20.97
3rqkB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.33A 3svpA-2i9uA:
undetectable
3svpB-2i9uA:
0.4		 3svpA-2i9uA:
20.97
3svpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 3svpA-2i9uA:
undetectable
3svpB-2i9uA:
0.4		 3svpA-2i9uA:
20.97
3svpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.33A 3svqA-2i9uA:
undetectable
3svqB-2i9uA:
undetectable		 3svqA-2i9uA:
20.97
3svqB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 3ufoA-2i9uA:
undetectable
3ufoB-2i9uA:
1.0		 3ufoA-2i9uA:
20.97
3ufoB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 3ufpA-2i9uA:
undetectable
3ufpB-2i9uA:
undetectable		 3ufpA-2i9uA:
20.97
3ufpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.45A 3ufpA-2i9uA:
undetectable
3ufpB-2i9uA:
undetectable		 3ufpA-2i9uA:
20.97
3ufpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.36A 3ufqA-2i9uA:
undetectable
3ufqB-2i9uA:
undetectable		 3ufqA-2i9uA:
20.97
3ufqB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 3ufqA-2i9uA:
undetectable
3ufqB-2i9uA:
undetectable		 3ufqA-2i9uA:
20.97
3ufqB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.45A 3ufrA-2i9uA:
undetectable
3ufrB-2i9uA:
undetectable		 3ufrA-2i9uA:
20.97
3ufrB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 3ufrA-2i9uA:
undetectable
3ufrB-2i9uA:
undetectable		 3ufrA-2i9uA:
20.97
3ufrB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 3ufsA-2i9uA:
undetectable
3ufsB-2i9uA:
undetectable		 3ufsA-2i9uA:
20.97
3ufsB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.37A 3uftA-2i9uA:
0.4
3uftB-2i9uA:
undetectable		 3uftA-2i9uA:
20.97
3uftB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.39A 3uftA-2i9uA:
0.4
3uftB-2i9uA:
undetectable		 3uftA-2i9uA:
20.97
3uftB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 3ufwA-2i9uA:
undetectable
3ufwB-2i9uA:
0.4		 3ufwA-2i9uA:
20.97
3ufwB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 GLN A  78
HIS A  75
HIS A  73
PHE A  99
VAL A 160
 GUN  A 503 (-3.4A)
FE  A 501 ( 3.6A)
FE  A 501 (-3.4A)
None
None
 1.08A 3v2jA-2i9uA:
undetectable		 3v2jA-2i9uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 LEU A 298
HIS A  73
HIS A  75
HIS A 229
 None
FE  A 501 (-3.4A)
FE  A 501 ( 3.6A)
GUN  A 503 ( 3.5A)
 0.92A 4a7bA-2i9uA:
undetectable		 4a7bA-2i9uA:
16.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		10 / 12 GLN A  78
LEU A  90
LEU A  94
ARG A 202
PHE A 203
HIS A 229
GLU A 232
HIS A 269
SER A 294
ASP A 320
 GUN  A 503 (-3.4A)
GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
GUN  A 503 (-3.7A)
GUN  A 503 (-3.5A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
GUN  A 503 ( 4.3A)
FE  A 501 ( 2.7A)
 0.56A 4aqlA-2i9uA:
56.5		 4aqlA-2i9uA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		10 / 12 GLN A  78
LEU A  94
ARG A 202
PHE A 203
HIS A 229
GLU A 232
GLU A 236
HIS A 269
SER A 294
ASP A 320
 GUN  A 503 (-3.4A)
GUN  A 503 (-4.4A)
GUN  A 503 (-3.7A)
GUN  A 503 (-3.5A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
GUN  A 503 ( 4.4A)
GUN  A 503 ( 4.3A)
FE  A 501 ( 2.7A)
 0.33A 4aqlA-2i9uA:
56.5		 4aqlA-2i9uA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
LEU A 298
HIS A 229
GLU A 232
HIS A 269
 GUN  A 503 (-3.4A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
 1.23A 4aqlA-2i9uA:
56.5		 4aqlA-2i9uA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLU A 232
GLU A 236
ALA A 238
HIS A 269
SER A 294
 GUN  A 503 (-3.1A)
None
None
GUN  A 503 ( 4.4A)
GUN  A 503 ( 4.3A)
 1.01A 4aqlA-2i9uA:
56.5		 4aqlA-2i9uA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 LEU A  90
GLU A 232
ALA A 238
HIS A 269
SER A 294
 GUN  A 503 (-4.9A)
GUN  A 503 (-3.1A)
None
GUN  A 503 ( 4.4A)
GUN  A 503 ( 4.3A)
 1.02A 4aqlA-2i9uA:
56.5		 4aqlA-2i9uA:
36.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 4c39A-2i9uA:
0.5
4c39B-2i9uA:
undetectable		 4c39A-2i9uA:
20.97
4c39B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 4camA-2i9uA:
undetectable
4camB-2i9uA:
0.4		 4camA-2i9uA:
20.97
4camB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 4camA-2i9uA:
undetectable
4camB-2i9uA:
0.4		 4camA-2i9uA:
20.97
4camB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4canA-2i9uA:
undetectable
4canB-2i9uA:
undetectable		 4canA-2i9uA:
20.97
4canB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4caoA-2i9uA:
undetectable
4caoB-2i9uA:
0.4		 4caoA-2i9uA:
20.97
4caoB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 4cdtA-2i9uA:
undetectable
4cdtB-2i9uA:
undetectable		 4cdtA-2i9uA:
20.97
4cdtB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.27A 4ctrA-2i9uA:
undetectable
4ctrB-2i9uA:
0.4		 4ctrA-2i9uA:
20.97
4ctrB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4ctrA-2i9uA:
undetectable
4ctrB-2i9uA:
undetectable		 4ctrA-2i9uA:
20.97
4ctrB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 4cttA-2i9uA:
undetectable
4cttB-2i9uA:
undetectable		 4cttA-2i9uA:
20.97
4cttB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4cx7A-2i9uA:
undetectable
4cx7B-2i9uA:
undetectable		 4cx7A-2i9uA:
21.31
4cx7B-2i9uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 4cx7C-2i9uA:
undetectable
4cx7D-2i9uA:
undetectable		 4cx7C-2i9uA:
21.31
4cx7D-2i9uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 ILE A 333
LEU A 329
ILE A  66
GLY A 368
 None
 0.74A 4hb6A-2i9uA:
undetectable		 4hb6A-2i9uA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 4imwA-2i9uA:
0.4
4imwB-2i9uA:
0.4		 4imwA-2i9uA:
20.97
4imwB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 4imwA-2i9uA:
0.4
4imwB-2i9uA:
0.4		 4imwA-2i9uA:
20.97
4imwB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4jsfA-2i9uA:
undetectable
4jsfB-2i9uA:
undetectable		 4jsfA-2i9uA:
20.97
4jsfB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.37A 4jshA-2i9uA:
undetectable
4jshB-2i9uA:
0.4		 4jshA-2i9uA:
20.97
4jshB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.42A 4jshA-2i9uA:
undetectable
4jshB-2i9uA:
0.4		 4jshA-2i9uA:
20.97
4jshB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4jsiA-2i9uA:
undetectable
4jsiB-2i9uA:
undetectable		 4jsiA-2i9uA:
20.97
4jsiB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 4k5dA-2i9uA:
undetectable
4k5dB-2i9uA:
0.4		 4k5dA-2i9uA:
20.97
4k5dB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.34A 4k5fA-2i9uA:
undetectable
4k5fB-2i9uA:
0.4		 4k5fA-2i9uA:
20.97
4k5fB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4k5fA-2i9uA:
undetectable
4k5fB-2i9uA:
0.4		 4k5fA-2i9uA:
20.97
4k5fB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4kciA-2i9uA:
undetectable
4kciB-2i9uA:
undetectable		 4kciA-2i9uA:
20.97
4kciB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.34A 4kckA-2i9uA:
undetectable
4kckB-2i9uA:
0.2		 4kckA-2i9uA:
20.97
4kckB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4kckA-2i9uA:
undetectable
4kckB-2i9uA:
0.2		 4kckA-2i9uA:
20.97
4kckB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 ARG A 202
HIS A 229
SER A 206
 GUN  A 503 (-3.7A)
GUN  A 503 ( 3.5A)
None
 1.01A 4mjwA-2i9uA:
undetectable
4mjwB-2i9uA:
undetectable		 4mjwA-2i9uA:
21.03
4mjwB-2i9uA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 SER A 206
ARG A 202
HIS A 229
 None
GUN  A 503 (-3.7A)
GUN  A 503 ( 3.5A)
 1.01A 4mjwA-2i9uA:
undetectable
4mjwB-2i9uA:
undetectable		 4mjwA-2i9uA:
21.03
4mjwB-2i9uA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 GLN A  78
HIS A 229
GLU A 232
LEU A  90
SER A 294
 GUN  A 503 (-3.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 4.3A)
 1.44A 4r88A-2i9uA:
31.3		 4r88A-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
HIS A 269
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 ( 4.4A)
None
FE  A 501 ( 2.7A)
 0.58A 4r88A-2i9uA:
31.3		 4r88A-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
LEU A 298
HIS A 229
HIS A 269
ASP A 320
 FE  A 501 ( 3.6A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 1.21A 4r88A-2i9uA:
31.3		 4r88A-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
PHE A 133
HIS A  73
HIS A 269
LEU A  90
 FE  A 501 ( 3.6A)
None
FE  A 501 (-3.4A)
GUN  A 503 ( 4.4A)
GUN  A 503 (-4.9A)
 1.33A 4r88A-2i9uA:
31.3		 4r88A-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 LEU A  94
GLN A  78
HIS A 229
LEU A  90
SER A 294
 GUN  A 503 (-4.4A)
GUN  A 503 (-3.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 4.3A)
 1.39A 4r88A-2i9uA:
31.3		 4r88A-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
GLU A 232
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
FE  A 501 ( 2.7A)
 0.47A 4r88B-2i9uA:
31.8		 4r88B-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
LEU A 298
HIS A 229
GLU A 232
ASP A 320
 FE  A 501 ( 3.6A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
FE  A 501 ( 2.7A)
 1.41A 4r88B-2i9uA:
31.8		 4r88B-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
GLU A 232
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
FE  A 501 ( 2.7A)
 0.48A 4r88C-2i9uA:
31.4		 4r88C-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
LEU A 298
HIS A 229
GLU A 232
ASP A 320
 FE  A 501 ( 3.6A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
FE  A 501 ( 2.7A)
 1.43A 4r88C-2i9uA:
31.4		 4r88C-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
GLU A 232
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
FE  A 501 ( 2.7A)
 0.51A 4r88D-2i9uA:
31.3		 4r88D-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A  75
LEU A 298
HIS A 229
GLU A 232
ASP A 320
 FE  A 501 ( 3.6A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
FE  A 501 ( 2.7A)
 1.43A 4r88D-2i9uA:
31.3		 4r88D-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
GLU A 232
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
FE  A 501 ( 2.7A)
 0.51A 4r88E-2i9uA:
31.1		 4r88E-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 HIS A  75
LEU A  90
HIS A 229
GLU A 232
LEU A 298
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
None
FE  A 501 ( 2.7A)
 0.50A 4r88F-2i9uA:
31.4		 4r88F-2i9uA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 4ugzA-2i9uA:
undetectable
4ugzB-2i9uA:
undetectable		 4ugzA-2i9uA:
20.97
4ugzB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4ugzA-2i9uA:
undetectable
4ugzB-2i9uA:
undetectable		 4ugzA-2i9uA:
20.97
4ugzB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 4uh0A-2i9uA:
undetectable
4uh0B-2i9uA:
undetectable		 4uh0A-2i9uA:
20.97
4uh0B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 4uh0A-2i9uA:
undetectable
4uh0B-2i9uA:
undetectable		 4uh0A-2i9uA:
20.97
4uh0B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 4uh2A-2i9uA:
undetectable
4uh2B-2i9uA:
undetectable		 4uh2A-2i9uA:
20.97
4uh2B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4uh2A-2i9uA:
undetectable
4uh2B-2i9uA:
undetectable		 4uh2A-2i9uA:
20.97
4uh2B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 4uh3A-2i9uA:
undetectable
4uh3B-2i9uA:
undetectable		 4uh3A-2i9uA:
20.97
4uh3B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.37A 4upnA-2i9uA:
undetectable
4upnB-2i9uA:
undetectable		 4upnA-2i9uA:
20.97
4upnB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 4upnA-2i9uA:
undetectable
4upnB-2i9uA:
undetectable		 4upnA-2i9uA:
20.97
4upnB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 4uppA-2i9uA:
undetectable
4uppB-2i9uA:
undetectable		 4uppA-2i9uA:
20.97
4uppB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 4uppA-2i9uA:
undetectable
4uppB-2i9uA:
undetectable		 4uppA-2i9uA:
20.97
4uppB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 GLU A 101
ALA A 103
PHE A 105
 None
 0.66A 4v1fC-2i9uA:
undetectable		 4v1fC-2i9uA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 4v3vA-2i9uA:
undetectable
4v3vB-2i9uA:
undetectable		 4v3vA-2i9uA:
20.97
4v3vB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 HIS A  73
HIS A 269
GLU A 232
HIS A 229
ALA A 323
 FE  A 501 (-3.4A)
GUN  A 503 ( 4.4A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 3.5A)
GUN  A 503 ( 4.1A)
 1.10A 4ygfD-2i9uA:
undetectable		 4ygfD-2i9uA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 11 HIS A  73
HIS A 269
GLU A 232
HIS A 229
ALA A 323
 FE  A 501 (-3.4A)
GUN  A 503 ( 4.4A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 3.5A)
GUN  A 503 ( 4.1A)
 1.15A 4yhaD-2i9uA:
undetectable		 4yhaD-2i9uA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.25A 5ad4A-2i9uA:
undetectable
5ad4B-2i9uA:
0.4		 5ad4A-2i9uA:
20.97
5ad4B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.32A 5ad4A-2i9uA:
undetectable
5ad4B-2i9uA:
0.4		 5ad4A-2i9uA:
20.97
5ad4B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.33A 5ad5A-2i9uA:
undetectable
5ad5B-2i9uA:
undetectable		 5ad5A-2i9uA:
20.97
5ad5B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 5ad5A-2i9uA:
undetectable
5ad5B-2i9uA:
undetectable		 5ad5A-2i9uA:
20.97
5ad5B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 5ad6A-2i9uA:
undetectable
5ad6B-2i9uA:
0.4		 5ad6A-2i9uA:
20.97
5ad6B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5ad6A-2i9uA:
0.5
5ad6B-2i9uA:
0.4		 5ad6A-2i9uA:
20.97
5ad6B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.39A 5ad7A-2i9uA:
undetectable
5ad7B-2i9uA:
0.4		 5ad7A-2i9uA:
20.97
5ad7B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5ad8A-2i9uA:
0.4
5ad8B-2i9uA:
0.4		 5ad8A-2i9uA:
20.97
5ad8B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.41A 5ad9A-2i9uA:
undetectable
5ad9B-2i9uA:
undetectable		 5ad9A-2i9uA:
20.97
5ad9B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.46A 5ad9A-2i9uA:
undetectable
5ad9B-2i9uA:
undetectable		 5ad9A-2i9uA:
20.97
5ad9B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.27A 5adaA-2i9uA:
undetectable
5adaB-2i9uA:
undetectable		 5adaA-2i9uA:
20.97
5adaB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5adaA-2i9uA:
undetectable
5adaB-2i9uA:
undetectable		 5adaA-2i9uA:
20.97
5adaB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.41A 5adbA-2i9uA:
undetectable
5adbB-2i9uA:
undetectable		 5adbA-2i9uA:
20.97
5adbB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.37A 5adiA-2i9uA:
undetectable
5adiB-2i9uA:
undetectable		 5adiA-2i9uA:
21.46
5adiB-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 5agoA-2i9uA:
undetectable
5agoB-2i9uA:
0.4		 5agoA-2i9uA:
20.97
5agoB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.35A 5agpA-2i9uA:
undetectable
5agpB-2i9uA:
undetectable		 5agpA-2i9uA:
20.97
5agpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.40A 5agpA-2i9uA:
undetectable
5agpB-2i9uA:
undetectable		 5agpA-2i9uA:
20.97
5agpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 PHE A  13
ILE A  34
LEU A 386
GLY A 380
PHE A 377
 None
 1.09A 5byjA-2i9uA:
undetectable		 5byjA-2i9uA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5fvpA-2i9uA:
0.5
5fvpB-2i9uA:
undetectable		 5fvpA-2i9uA:
20.97
5fvpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.42A 5fvpA-2i9uA:
0.5
5fvpB-2i9uA:
undetectable		 5fvpA-2i9uA:
20.97
5fvpB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5fw0A-2i9uA:
undetectable
5fw0B-2i9uA:
0.3		 5fw0A-2i9uA:
20.97
5fw0B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 5g0oA-2i9uA:
0.4
5g0oB-2i9uA:
undetectable		 5g0oA-2i9uA:
20.97
5g0oB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 5g0oA-2i9uA:
0.4
5g0oB-2i9uA:
undetectable		 5g0oA-2i9uA:
20.97
5g0oB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 5 ALA A 323
GLY A 318
CYH A 291
HIS A 269
 GUN  A 503 ( 4.1A)
None
None
GUN  A 503 ( 4.4A)
 1.34A 5jliA-2i9uA:
undetectable		 5jliA-2i9uA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 5 ALA A 323
GLY A 318
CYH A 291
HIS A 269
 GUN  A 503 ( 4.1A)
None
None
GUN  A 503 ( 4.4A)
 1.36A 5jt4A-2i9uA:
undetectable		 5jt4A-2i9uA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 THR A 114
ALA A 111
ILE A 119
LEU A 148
MET A 147
 None
 0.85A 5nfjA-2i9uA:
undetectable		 5nfjA-2i9uA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 ILE A 288
PHE A 133
SER A  77
ALA A 323
ALA A  74
 None
None
None
GUN  A 503 ( 4.1A)
None
 1.32A 5oy02-2i9uA:
undetectable		 5oy02-2i9uA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 HIS A  73
SER A 228
ARG A 202
 FE  A 501 (-3.4A)
None
GUN  A 503 (-3.7A)
 0.97A 5u63A-2i9uA:
undetectable		 5u63A-2i9uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 5unuA-2i9uA:
0.4
5unuB-2i9uA:
undetectable		 5unuA-2i9uA:
20.97
5unuB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.28A 5unvA-2i9uA:
0.4
5unvB-2i9uA:
0.3		 5unvA-2i9uA:
20.97
5unvB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 5unwA-2i9uA:
0.5
5unwB-2i9uA:
undetectable		 5unwA-2i9uA:
20.97
5unwB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.49A 5unwA-2i9uA:
0.5
5unwB-2i9uA:
undetectable		 5unwA-2i9uA:
20.97
5unwB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.35A 5unxA-2i9uA:
0.6
5unxB-2i9uA:
0.4		 5unxA-2i9uA:
20.97
5unxB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.48A 5unxA-2i9uA:
0.6
5unxB-2i9uA:
0.4		 5unxA-2i9uA:
20.97
5unxB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5unyA-2i9uA:
undetectable
5unyB-2i9uA:
undetectable		 5unyA-2i9uA:
20.97
5unyB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.36A 5unyA-2i9uA:
undetectable
5unyB-2i9uA:
undetectable		 5unyA-2i9uA:
20.97
5unyB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5unzA-2i9uA:
undetectable
5unzB-2i9uA:
undetectable		 5unzA-2i9uA:
20.97
5unzB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5uo0A-2i9uA:
undetectable
5uo0B-2i9uA:
undetectable		 5uo0A-2i9uA:
20.97
5uo0B-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 5uo3A-2i9uA:
0.5
5uo3B-2i9uA:
undetectable		 5uo3A-2i9uA:
21.46
5uo3B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.42A 5uo6A-2i9uA:
undetectable
5uo6B-2i9uA:
0.4		 5uo6A-2i9uA:
21.46
5uo6B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5uo9C-2i9uA:
0.0
5uo9D-2i9uA:
0.0		 5uo9C-2i9uA:
20.20
5uo9D-2i9uA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 5vuiA-2i9uA:
0.4
5vuiB-2i9uA:
undetectable		 5vuiA-2i9uA:
20.97
5vuiB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 5vuiA-2i9uA:
0.4
5vuiB-2i9uA:
undetectable		 5vuiA-2i9uA:
20.97
5vuiB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.16A 5vujA-2i9uA:
undetectable
5vujB-2i9uA:
0.8		 5vujA-2i9uA:
20.97
5vujB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.24A 5vujA-2i9uA:
undetectable
5vujB-2i9uA:
0.8		 5vujA-2i9uA:
20.97
5vujB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.28A 5vukA-2i9uA:
undetectable
5vukB-2i9uA:
0.4		 5vukA-2i9uA:
20.97
5vukB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 5vukA-2i9uA:
undetectable
5vukB-2i9uA:
0.0		 5vukA-2i9uA:
20.97
5vukB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 5vulA-2i9uA:
0.4
5vulB-2i9uA:
undetectable		 5vulA-2i9uA:
20.97
5vulB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 5vulA-2i9uA:
0.4
5vulB-2i9uA:
undetectable		 5vulA-2i9uA:
20.97
5vulB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 5vumA-2i9uA:
undetectable
5vumB-2i9uA:
undetectable		 5vumA-2i9uA:
20.97
5vumB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5vuoA-2i9uA:
undetectable
5vuoB-2i9uA:
undetectable		 5vuoA-2i9uA:
20.97
5vuoB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5vuqA-2i9uA:
undetectable
5vuqB-2i9uA:
undetectable		 5vuqA-2i9uA:
20.97
5vuqB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 5vuqA-2i9uA:
undetectable
5vuqB-2i9uA:
undetectable		 5vuqA-2i9uA:
20.97
5vuqB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5vurA-2i9uA:
undetectable
5vurB-2i9uA:
undetectable		 5vurA-2i9uA:
20.97
5vurB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.29A 5vusA-2i9uA:
undetectable
5vusB-2i9uA:
0.4		 5vusA-2i9uA:
20.97
5vusB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.31A 5vusA-2i9uA:
undetectable
5vusB-2i9uA:
0.4		 5vusA-2i9uA:
20.97
5vusB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 5vuuA-2i9uA:
undetectable
5vuuB-2i9uA:
0.0		 5vuuA-2i9uA:
20.97
5vuuB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5vuuA-2i9uA:
undetectable
5vuuB-2i9uA:
0.0		 5vuuA-2i9uA:
20.97
5vuuB-2i9uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5vuvA-2i9uA:
undetectable
5vuvB-2i9uA:
0.5		 5vuvA-2i9uA:
21.46
5vuvB-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.31A 5vuyA-2i9uA:
0.4
5vuyB-2i9uA:
undetectable		 5vuyA-2i9uA:
21.46
5vuyB-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.35A 5vuyA-2i9uA:
0.4
5vuyB-2i9uA:
undetectable		 5vuyA-2i9uA:
21.46
5vuyB-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.30A 5vuzA-2i9uA:
undetectable
5vuzB-2i9uA:
undetectable		 5vuzA-2i9uA:
21.46
5vuzB-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.35A 5vv0A-2i9uA:
0.4
5vv0B-2i9uA:
undetectable		 5vv0A-2i9uA:
21.46
5vv0B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.32A 5vv0A-2i9uA:
0.4
5vv0B-2i9uA:
undetectable		 5vv0A-2i9uA:
21.46
5vv0B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 5vv1A-2i9uA:
undetectable
5vv1B-2i9uA:
0.4		 5vv1A-2i9uA:
21.46
5vv1B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.25A 5vv1A-2i9uA:
undetectable
5vv1B-2i9uA:
0.4		 5vv1A-2i9uA:
21.46
5vv1B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 5vv2A-2i9uA:
0.4
5vv2B-2i9uA:
undetectable		 5vv2A-2i9uA:
21.46
5vv2B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5vv3A-2i9uA:
undetectable
5vv3B-2i9uA:
undetectable		 5vv3A-2i9uA:
21.46
5vv3B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 5vv3A-2i9uA:
undetectable
5vv3B-2i9uA:
undetectable		 5vv3A-2i9uA:
21.46
5vv3B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.34A 5vv4A-2i9uA:
undetectable
5vv4B-2i9uA:
0.4		 5vv4A-2i9uA:
21.46
5vv4B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.32A 5vv5A-2i9uA:
0.4
5vv5B-2i9uA:
0.4		 5vv5A-2i9uA:
21.46
5vv5B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.39A 5vv5A-2i9uA:
0.4
5vv5B-2i9uA:
0.4		 5vv5A-2i9uA:
21.46
5vv5B-2i9uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 5 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.30A 5vvbC-2i9uA:
0.0
5vvbD-2i9uA:
0.0		 5vvbC-2i9uA:
20.20
5vvbD-2i9uA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.33A 5vvcC-2i9uA:
0.0
5vvcD-2i9uA:
0.0		 5vvcC-2i9uA:
20.20
5vvcD-2i9uA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.27A 6auqA-2i9uA:
0.4
6auqB-2i9uA:
1.0		 6auqA-2i9uA:
10.67
6auqB-2i9uA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.38A 6auqA-2i9uA:
0.4
6auqB-2i9uA:
1.0		 6auqA-2i9uA:
10.67
6auqB-2i9uA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.42A 6auuA-2i9uA:
undetectable
6auuB-2i9uA:
0.0		 6auuA-2i9uA:
10.67
6auuB-2i9uA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ARG A 202
TRP A  93
PHE A  99
GLU A 101
 GUN  A 503 (-3.7A)
None
None
None
 1.33A 6auxA-2i9uA:
undetectable
6auxB-2i9uA:
undetectable		 6auxA-2i9uA:
10.67
6auxB-2i9uA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.37A 6auxA-2i9uA:
undetectable
6auxB-2i9uA:
undetectable		 6auxA-2i9uA:
10.67
6auxB-2i9uA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		4 / 6 PHE A  99
GLU A 101
ARG A 202
TRP A  93
 None
None
GUN  A 503 (-3.7A)
None
 1.29A 6cifC-2i9uA:
0.0
6cifD-2i9uA:
0.0		 6cifC-2i9uA:
8.80
6cifD-2i9uA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		7 / 12 HIS A  75
LEU A  90
LEU A  94
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.71A 6n91A-2i9uA:
22.4		 6n91A-2i9uA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A 269
LEU A  94
LEU A  90
ALA A 323
HIS A  75
 GUN  A 503 ( 4.4A)
GUN  A 503 (-4.4A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 4.1A)
FE  A 501 ( 3.6A)
 1.31A 6n91A-2i9uA:
22.4		 6n91A-2i9uA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 LEU A  90
LEU A  94
SER A 206
HIS A 229
GLU A 232
HIS A 269
 GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
 1.05A 6n91A-2i9uA:
22.4		 6n91A-2i9uA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		7 / 12 HIS A  75
LEU A  90
LEU A  94
HIS A 229
GLU A 232
HIS A 269
ASP A 320
 FE  A 501 ( 3.6A)
GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
FE  A 501 ( 2.7A)
 0.80A 6n91B-2i9uA:
22.4		 6n91B-2i9uA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		5 / 12 HIS A 269
LEU A  94
LEU A  90
ALA A 323
HIS A  75
 GUN  A 503 ( 4.4A)
GUN  A 503 (-4.4A)
GUN  A 503 (-4.9A)
GUN  A 503 ( 4.1A)
FE  A 501 ( 3.6A)
 1.23A 6n91B-2i9uA:
22.4		 6n91B-2i9uA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2i9u CYTOSINE/GUANINE
DEAMINASE RELATED
PROTEIN
(Clostridium
acetobutylicum) 		6 / 12 LEU A  90
LEU A  94
SER A 206
HIS A 229
GLU A 232
HIS A 269
 GUN  A 503 (-4.9A)
GUN  A 503 (-4.4A)
None
GUN  A 503 ( 3.5A)
GUN  A 503 (-3.1A)
GUN  A 503 ( 4.4A)
 1.02A 6n91B-2i9uA:
22.4		 6n91B-2i9uA:
10.90