SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_B_CUB4_0
(BETA-CARBONIC
ANHYDRASE)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		4 / 6 CYH A  29
CYH A  10
PRO A   9
SER A  61
 ZN  A 200 (-2.3A)
ZN  A 200 (-2.3A)
None
ZN  A 200 ( 3.8A)
 1.39A 1ekjA-2i9wA:
0.0
1ekjB-2i9wA:
0.0		 1ekjA-2i9wA:
23.28
1ekjB-2i9wA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		4 / 7 CYH A  10
TYR A  60
CYH A  29
HIS A  33
 ZN  A 200 (-2.3A)
None
ZN  A 200 (-2.3A)
None
 1.48A 1yvmA-2i9wA:
undetectable		 1yvmA-2i9wA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		3 / 3 HIS A 132
GLU A 133
HIS A 131
 None
 0.85A 3ba0A-2i9wA:
undetectable		 3ba0A-2i9wA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		4 / 6 LEU A  83
ALA A  78
LEU A  76
THR A  75
 None
 0.97A 3rozA-2i9wA:
undetectable		 3rozA-2i9wA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		4 / 7 ALA A  49
THR A  51
ALA A  52
THR A  58
 None
 0.99A 4qw0K-2i9wA:
undetectable		 4qw0K-2i9wA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2i9w HYPOTHETICAL PROTEIN
(Psychrobacter
arcticus) 		4 / 7 ALA A  49
THR A  51
ALA A  52
THR A  58
 None
 0.99A 4qw0Y-2i9wA:
undetectable		 4qw0Y-2i9wA:
21.39