SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		5 / 10 SER A  49
ARG A  35
LEU A  34
ALA A  46
ILE A  72
 None
 1.20A 1g5yC-2i9xA:
undetectable		 1g5yC-2i9xA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		3 / 3 MET A  77
MET A  68
PHE A  44
 None
 1.32A 3gn8A-2i9xA:
undetectable		 3gn8A-2i9xA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A   3
VAL A  45
ILE A  31
MET A  77
 None
 0.99A 3mssD-2i9xA:
undetectable		 3mssD-2i9xA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 7 PRO A  48
ILE A  31
LEU A  25
ILE A  72
 None
 0.95A 3p50A-2i9xA:
undetectable		 3p50A-2i9xA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 7 PRO A  48
ILE A  31
LEU A  25
ILE A  72
 None
 0.95A 3p50C-2i9xA:
undetectable		 3p50C-2i9xA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 7 PRO A  48
ILE A  31
LEU A  25
ILE A  72
 None
 0.97A 3p50D-2i9xA:
undetectable		 3p50D-2i9xA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 7 PRO A  48
ILE A  31
LEU A  25
ILE A  72
 None
 0.96A 3p50E-2i9xA:
undetectable		 3p50E-2i9xA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 EDO  A 101 ( 4.7A)
EDO  A 101 ( 4.9A)
EDO  A 101 (-4.6A)
EDO  A 101 (-3.7A)
 0.74A 3tj7A-2i9xA:
undetectable
3tj7B-2i9xA:
undetectable		 3tj7A-2i9xA:
20.21
3tj7B-2i9xA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 EDO  A 101 ( 4.7A)
EDO  A 101 ( 4.9A)
EDO  A 101 (-4.6A)
EDO  A 101 (-3.7A)
 0.66A 3tj7C-2i9xA:
undetectable
3tj7D-2i9xA:
undetectable		 3tj7C-2i9xA:
20.21
3tj7D-2i9xA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 EDO  A 101 ( 4.7A)
EDO  A 101 ( 4.9A)
EDO  A 101 (-4.6A)
EDO  A 101 (-3.7A)
 0.67A 3tj7C-2i9xA:
undetectable
3tj7D-2i9xA:
undetectable		 3tj7C-2i9xA:
20.21
3tj7D-2i9xA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		5 / 12 LEU A  34
VAL A  45
GLN A  70
ILE A  72
ILE A  23
 None
 1.09A 4ltwA-2i9xA:
undetectable		 4ltwA-2i9xA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		3 / 3 SER A  66
LEU A  25
MET A   1
 None
 0.86A 5ikrB-2i9xA:
undetectable		 5ikrB-2i9xA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 2i9x PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 5 THR A   4
GLU A  71
HIS A  62
LEU A  34
 None
 1.20A 5utuH-2i9xA:
undetectable		 5utuH-2i9xA:
11.38