SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2i9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		3 / 3 MET A  77
MET A  68
PHE A  44
 None
None
EDO  A 104 (-4.7A)
 1.30A 3gn8A-2i9zA:
undetectable		 3gn8A-2i9zA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A   3
VAL A  45
ILE A  31
MET A  77
 None
 0.88A 3mssD-2i9zA:
undetectable		 3mssD-2i9zA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 None
 0.71A 3tj7A-2i9zA:
undetectable
3tj7B-2i9zA:
undetectable		 3tj7A-2i9zA:
25.15
3tj7B-2i9zA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 None
 0.63A 3tj7C-2i9zA:
undetectable
3tj7D-2i9zA:
undetectable		 3tj7C-2i9zA:
25.15
3tj7D-2i9zA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		4 / 6 VAL A  30
HIS A  32
SER A  22
THR A  24
 None
 0.64A 3tj7C-2i9zA:
undetectable
3tj7D-2i9zA:
undetectable		 3tj7C-2i9zA:
25.15
3tj7D-2i9zA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		3 / 3 SER A  66
LEU A  25
MET A   1
 None
 0.87A 5ikrB-2i9zA:
undetectable		 5ikrB-2i9zA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 2i9z PUTATIVE SEPTATION
PROTEIN SPOVG
(Staphylococcus
epidermidis) 		3 / 3 VAL A  76
LYS A   2
MET A   1
 None
 0.86A 5nknA-2i9zA:
undetectable		 5nknA-2i9zA:
19.81