SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ia7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SV9_A_DIFA701_1 (PHOSPHOLIPASE A2)	2ia7	TAIL LYSOZYME, PUTATIVE (Geobacter sulfurreducens)	4 / 8	ILE A 39 CYH A 56 GLY A 55 PHE A 127	None	0.80A	1sv9A-2ia7A: undetectable	1sv9A-2ia7A: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUM_A_Z80A201_1 (BETA-LACTOGLOBULIN)	2ia7	TAIL LYSOZYME, PUTATIVE (Geobacter sulfurreducens)	5 / 8	VAL A 78 ILE A 40 LEU A 41 ILE A 37 ILE A 89	None	1.09A	5numA-2ia7A: undetectable	5numA-2ia7A: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_A_FFOA403_0 (THYMIDYLATE SYNTHASE)	2ia7	TAIL LYSOZYME, PUTATIVE (Geobacter sulfurreducens)	5 / 12	PHE A 127 ILE A 108 LEU A 71 GLY A 72 ASN A 76	None	1.23A	6r2eA-2ia7A: undetectable	6r2eA-2ia7A: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_F_FFOF403_0 (THYMIDYLATE SYNTHASE)	2ia7	TAIL LYSOZYME, PUTATIVE (Geobacter sulfurreducens)	5 / 11	PHE A 127 ILE A 108 LEU A 71 GLY A 72 ASN A 76	None	1.21A	6r2eF-2ia7A: undetectable	6r2eF-2ia7A: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_G_FFOG403_0 (THYMIDYLATE SYNTHASE)	2ia7	TAIL LYSOZYME, PUTATIVE (Geobacter sulfurreducens)	5 / 11	PHE A 127 ILE A 108 LEU A 71 GLY A 72 ASN A 76	None	1.24A	6r2eG-2ia7A: undetectable	6r2eG-2ia7A: 15.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SV9_A_DIFA701_1","PHOSPHOLIPASE A2","2ia7","TAIL LYSOZYME, PUTATIVE","Geobacter sulfurreducens",4,"ILE A  39;CYH A  56;GLY A  55;PHE A 127","None","0.80A","1sv9A-2ia7A:undetectable","1sv9A-2ia7A:19.29"],["5NUM_A_Z80A201_1","BETA-LACTOGLOBULIN","2ia7","TAIL LYSOZYME, PUTATIVE","Geobacter sulfurreducens",5,"VAL A  78;ILE A  40;LEU A  41;ILE A  37;ILE A  89","None","1.09A","5numA-2ia7A:undetectable","5numA-2ia7A:19.40"],["6R2E_A_FFOA403_0","THYMIDYLATE SYNTHASE","2ia7","TAIL LYSOZYME, PUTATIVE","Geobacter sulfurreducens",5,"PHE A 127;ILE A 108;LEU A  71;GLY A  72;ASN A  76","None","1.23A","6r2eA-2ia7A:undetectable","6r2eA-2ia7A:15.84"],["6R2E_F_FFOF403_0","THYMIDYLATE SYNTHASE","2ia7","TAIL LYSOZYME, PUTATIVE","Geobacter sulfurreducens",5,"PHE A 127;ILE A 108;LEU A  71;GLY A  72;ASN A  76","None","1.21A","6r2eF-2ia7A:undetectable","6r2eF-2ia7A:15.84"],["6R2E_G_FFOG403_0","THYMIDYLATE SYNTHASE","2ia7","TAIL LYSOZYME, PUTATIVE","Geobacter sulfurreducens",5,"PHE A 127;ILE A 108;LEU A  71;GLY A  72;ASN A  76","None","1.24A","6r2eG-2ia7A:undetectable","6r2eG-2ia7A:15.84"]]