SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iak'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2iak BULLOUS PEMPHIGOID
ANTIGEN 1, ISOFORM 5
(Mus
musculus) 		4 / 8 ARG A 128
ASN A 124
PHE A 125
ASN A 131
 None
 1.34A 1zzuA-2iakA:
undetectable		 1zzuA-2iakA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 2iak BULLOUS PEMPHIGOID
ANTIGEN 1, ISOFORM 5
(Mus
musculus) 		4 / 6 LEU A 186
ASP A 120
LEU A  59
HIS A 123
 None
 1.25A 3bj8C-2iakA:
undetectable
3bj8D-2iakA:
undetectable		 3bj8C-2iakA:
21.79
3bj8D-2iakA:
21.79