SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_A_SALA3005_1 (TRANSCRIPTIONAL REGULATOR TCAR)	2iay	HYPOTHETICAL PROTEIN (Lactobacillus plantarum)	4 / 8	ASN A 83 LEU A 97 ALA A 93 ARG A 98	None	1.03A	3kp6A-2iayA: undetectable	3kp6A-2iayA: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_2 (ESTROGEN RECEPTOR)	2iay	HYPOTHETICAL PROTEIN (Lactobacillus plantarum)	4 / 5	LEU A 46 GLU A 43 MET A 71 LEU A 9	None GOL A 115 (-4.7A) None None	1.30A	4xi3B-2iayA: undetectable	4xi3B-2iayA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJE_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2iay	HYPOTHETICAL PROTEIN (Lactobacillus plantarum)	5 / 12	LEU A 18 LEU A 66 LEU A 58 PHE A 40 ILE A 109	None	1.02A	5ljeA-2iayA: undetectable	5ljeA-2iayA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QYA_D_FOZD401_0 (THYMIDYLATE SYNTHASE)	2iay	HYPOTHETICAL PROTEIN (Lactobacillus plantarum)	5 / 12	LEU A 58 LEU A 30 GLY A 31 PHE A 42 ILE A 109	None	1.12A	6qyaD-2iayA: undetectable	6qyaD-2iayA: 17.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP6_A_SALA3005_1","TRANSCRIPTIONAL REGULATOR TCAR","2iay","HYPOTHETICAL PROTEIN","Lactobacillus plantarum",4,"ASN A  83;LEU A  97;ALA A  93;ARG A  98","None","1.03A","3kp6A-2iayA:undetectable","3kp6A-2iayA:19.87"],["4XI3_B_29SB601_2","ESTROGEN RECEPTOR","2iay","HYPOTHETICAL PROTEIN","Lactobacillus plantarum",4,"LEU A  46;GLU A  43;MET A  71;LEU A   9","None;GOL A 115 (-4.7A);None;None","1.30A","4xi3B-2iayA:undetectable","4xi3B-2iayA:16.88"],["5LJE_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2iay","HYPOTHETICAL PROTEIN","Lactobacillus plantarum",5,"LEU A  18;LEU A  66;LEU A  58;PHE A  40;ILE A 109","None","1.02A","5ljeA-2iayA:undetectable","5ljeA-2iayA:22.22"],["6QYA_D_FOZD401_0","THYMIDYLATE SYNTHASE","2iay","HYPOTHETICAL PROTEIN","Lactobacillus plantarum",5,"LEU A  58;LEU A  30;GLY A  31;PHE A  42;ILE A 109","None","1.12A","6qyaD-2iayA:undetectable","6qyaD-2iayA:17.65"]]