SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ib0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 MET A 106
GLU A  33
ASP A  67
 None
 1.03A 3a25A-2ib0A:
undetectable		 3a25A-2ib0A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 MET A 140
GLU A  33
ASP A  67
 None
 0.89A 3a25A-2ib0A:
undetectable		 3a25A-2ib0A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TYR A  38
LEU A  26
ARG A  66
 None
 0.79A 3sufB-2ib0A:
undetectable		 3sufB-2ib0A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 147
LEU A 148
LEU A 102
VAL A 104
LEU A  54
 None
 0.95A 4otyA-2ib0A:
undetectable		 4otyA-2ib0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 147
LEU A 148
LEU A 102
VAL A 104
LEU A  54
 None
 0.96A 4otyB-2ib0A:
undetectable		 4otyB-2ib0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 147
LEU A 148
LEU A 102
VAL A 104
LEU A  54
 None
 0.86A 4rrwD-2ib0A:
undetectable		 4rrwD-2ib0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 147
LEU A 148
LEU A 102
VAL A 104
LEU A  54
 None
 0.86A 4rrzD-2ib0A:
undetectable		 4rrzD-2ib0A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 2ib0 CONSERVED
HYPOTHETICAL ALANINE
RICH PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 HIS A  64
ASP A  67
ARG A  66
ARG A  65
 None
 1.05A 4uhxA-2ib0A:
undetectable		 4uhxA-2ib0A:
8.59