SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ibg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		5 / 12 LEU E 166
ASN E 167
LEU E 169
ALA E 170
MET E 158
 None
 1.06A 1ya3C-2ibgE:
undetectable		 1ya3C-2ibgE:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		5 / 12 LEU E 166
ASN E 167
LEU E 169
ALA E 170
MET E 158
 None
 1.08A 2aa6A-2ibgE:
undetectable		 2aa6A-2ibgE:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		3 / 3 GLU E 113
LEU E 199
LEU E 166
 None
 0.71A 3ohtA-2ibgE:
undetectable		 3ohtA-2ibgE:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		3 / 3 GLU E 113
LEU E 199
LEU E 166
 None
 0.68A 3ohtB-2ibgE:
undetectable		 3ohtB-2ibgE:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		3 / 3 HIS E 200
SER E 119
GLU E 113
 None
 0.82A 3s8pA-2ibgE:
undetectable		 3s8pA-2ibgE:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 2ibg PROTEIN HEDGEHOG
(Drosophila
melanogaster) 		5 / 12 LEU E 166
ASN E 167
LEU E 169
ALA E 170
MET E 158
 None
 1.05A 4fn9B-2ibgE:
undetectable		 4fn9B-2ibgE:
19.43