SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ibl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 2ibl FIBRITIN
(Escherichia
virus
T4;
Enterobacteria
phage
Ox2) 		3 / 3 ALA A  94
VAL A 103
TRP A 102
 None
 0.87A 1grmA-2iblA:
undetectable		 1grmA-2iblA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 2ibl FIBRITIN
(Escherichia
virus
T4;
Enterobacteria
phage
Ox2) 		3 / 3 ALA A  94
VAL A 103
TRP A 102
 None
 0.87A 1grmB-2iblA:
undetectable		 1grmB-2iblA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2ibl FIBRITIN
(Escherichia
virus
T4;
Enterobacteria
phage
Ox2) 		3 / 3 ALA A  94
VAL A 103
TRP A 102
 None
 0.91A 1jo4A-2iblA:
undetectable		 1jo4A-2iblA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2ibl FIBRITIN
(Escherichia
virus
T4;
Enterobacteria
phage
Ox2) 		3 / 3 ALA A  94
VAL A 103
TRP A 102
 None
 0.91A 1jo4B-2iblA:
undetectable		 1jo4B-2iblA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2ibl FIBRITIN
(Enterobacteria
phage
Ox2;
Escherichia
virus
T4) 		3 / 3 THR A  48
LEU A  52
VAL A  55
 None
 0.31A 1mz9E-2iblA:
3.0		 1mz9E-2iblA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2ibl FIBRITIN
(Enterobacteria
phage
Ox2;
Escherichia
virus
T4) 		5 / 12 ALA A  34
ASP A  35
ILE A  31
PRO A  47
THR A  48
 None
 0.85A 3el5B-2iblA:
undetectable		 3el5B-2iblA:
21.71