SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ice'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 8 LEU A 471
ALA A 620
GLY A 615
VAL A 510
 None
 0.73A 1d4sB-2iceA:
undetectable		 1d4sB-2iceA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 7 LEU A 266
THR A 246
SER A 305
THR A 307
 None
 0.63A 1ictD-2iceA:
3.8		 1ictD-2iceA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 11 LEU A 471
GLY A 621
ALA A 620
GLY A 615
VAL A 510
 None
 0.84A 1t7jA-2iceA:
undetectable		 1t7jA-2iceA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 ARG A 456
ASP A 527
ASP A 619
 None
 0.85A 2ejtA-2iceA:
undetectable		 2ejtA-2iceA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.28A 2y69C-2iceA:
undetectable
2y69J-2iceA:
undetectable		 2y69C-2iceA:
17.76
2y69J-2iceA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.26A 2y69P-2iceA:
undetectable
2y69W-2iceA:
undetectable		 2y69P-2iceA:
17.76
2y69W-2iceA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 269
ALA A 235
GLY A 274
GLY A 276
LEU A 238
 None
 0.96A 2y7hB-2iceA:
undetectable		 2y7hB-2iceA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 269
ALA A 235
GLY A 274
GLY A 276
LEU A 238
 None
 0.96A 2y7hC-2iceA:
undetectable		 2y7hC-2iceA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.97A 2zj0B-2iceA:
undetectable		 2zj0B-2iceA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.30A 3abmC-2iceA:
undetectable
3abmJ-2iceA:
undetectable		 3abmC-2iceA:
17.76
3abmJ-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.34A 3abmP-2iceA:
undetectable
3abmW-2iceA:
undetectable		 3abmP-2iceA:
17.76
3abmW-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.34A 3ag3C-2iceA:
undetectable
3ag3J-2iceA:
undetectable		 3ag3C-2iceA:
17.76
3ag3J-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 11 ALA A 306
VAL A 278
ILE A 324
LEU A 229
PHE A 251
 None
 0.99A 3fl9C-2iceA:
undetectable		 3fl9C-2iceA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 10 ALA A 306
VAL A 278
ILE A 324
LEU A 229
PHE A 251
 None
 1.07A 3fl9E-2iceA:
undetectable		 3fl9E-2iceA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 12 ALA A 306
VAL A 278
ILE A 324
LEU A 229
PHE A 251
 None
 1.01A 3fl9G-2iceA:
undetectable		 3fl9G-2iceA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 4 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 1.02A 3g1uA-2iceA:
undetectable		 3g1uA-2iceA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 1.02A 3g1uC-2iceA:
undetectable		 3g1uC-2iceA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 GLU A  23
HIS A  25
THR A 469
 None
 0.77A 3hkuA-2iceA:
undetectable		 3hkuA-2iceA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 8 ASN A 390
ASP A 349
SER A 437
HIS A 435
 None
 1.12A 3sg9B-2iceA:
undetectable		 3sg9B-2iceA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 9 LEU A 471
GLY A 621
ALA A 620
GLY A 615
VAL A 510
 None
 0.76A 3u7sA-2iceA:
undetectable		 3u7sA-2iceA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 6 GLY A 610
VAL A 616
ASP A 619
THR A 606
 None
 1.09A 3vqrA-2iceA:
undetectable		 3vqrA-2iceA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLY A 610
VAL A 616
ASP A 619
THR A 606
 None
 1.09A 3vqrB-2iceA:
undetectable		 3vqrB-2iceA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 7 LEU A 266
THR A 246
SER A 305
THR A 307
 None
 0.89A 4d7bA-2iceA:
4.1		 4d7bA-2iceA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 8 VAL A 529
ASP A 349
ASN A 452
HIS A 435
 None
 0.94A 4exsB-2iceA:
undetectable		 4exsB-2iceA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 8 LEU A 266
THR A 246
SER A 305
THR A 307
 None
 0.73A 4ik7B-2iceA:
undetectable		 4ik7B-2iceA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 10 ALA A 319
VAL A 308
ILE A 250
VAL A 231
VAL A 214
 None
 1.04A 4j5jB-2iceA:
undetectable		 4j5jB-2iceA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.99A 4lvcA-2iceA:
undetectable		 4lvcA-2iceA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 1.00A 4lvcC-2iceA:
undetectable		 4lvcC-2iceA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 LEU A 297
ILE A 223
ARG A 282
 None
 0.70A 4mk4B-2iceA:
undetectable		 4mk4B-2iceA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 LEU A 164
LEU A 108
ASN A 131
 None
 0.62A 4otwA-2iceA:
undetectable		 4otwA-2iceA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 ARG A 522
SER A 628
SER A 627
SER A   5
 None
 1.16A 5hswA-2iceA:
undetectable		 5hswA-2iceA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 VAL A 354
TYR A 331
GLN A 332
 None
 0.75A 5qgkA-2iceA:
undetectable		 5qgkA-2iceA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 VAL A 354
TYR A 331
GLN A 332
 None
 0.72A 5qgrA-2iceA:
undetectable		 5qgrA-2iceA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		3 / 3 VAL A 354
TYR A 331
GLN A 332
 None
 0.74A 5qgtA-2iceA:
undetectable		 5qgtA-2iceA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.33A 5wauC-2iceA:
undetectable
5wauJ-2iceA:
undetectable		 5wauC-2iceA:
17.76
5wauJ-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.33A 5wauc-2iceA:
undetectable
5wauj-2iceA:
undetectable		 5wauc-2iceA:
17.76
5wauj-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 12 PRO A 357
GLY A 359
LYS A 300
ASP A 255
GLY A 256
 None
 1.17A 5wwsA-2iceA:
undetectable		 5wwsA-2iceA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		6 / 12 PRO A 357
GLY A 359
LYS A 300
ILE A 326
ASP A 255
GLY A 256
 None
 1.18A 5wwsB-2iceA:
undetectable		 5wwsB-2iceA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 8 LYS A 578
PHE A 210
GLY A 240
PHE A 237
 None
 0.83A 5x5qD-2iceA:
undetectable		 5x5qD-2iceA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.32A 5xdqC-2iceA:
undetectable
5xdqJ-2iceA:
undetectable		 5xdqC-2iceA:
17.76
5xdqJ-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 PHE A 342
PHE A 348
LEU A 350
PHE A 335
 None
 1.33A 5xdqP-2iceA:
undetectable
5xdqW-2iceA:
undetectable		 5xdqP-2iceA:
17.76
5xdqW-2iceA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.99A 6aphA-2iceA:
undetectable		 6aphA-2iceA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.94A 6gbnA-2iceA:
undetectable		 6gbnA-2iceA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.95A 6gbnB-2iceA:
undetectable		 6gbnB-2iceA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.94A 6gbnC-2iceA:
undetectable		 6gbnC-2iceA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		4 / 5 GLN A 631
THR A 632
THR A 514
HIS A  25
 None
 0.92A 6gbnD-2iceA:
undetectable		 6gbnD-2iceA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2ice COMPLEMENT C3 BETA
CHAIN
(Homo
sapiens) 		5 / 12 PRO A 270
ILE A 269
ILE A 271
THR A 232
ILE A 233
 None
 1.06A 6hlpA-2iceA:
undetectable		 6hlpA-2iceA:
23.03