SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2idc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 8 ASP A  20
ALA A  16
ILE A 139
ILE A 135
PRO A  79
 None
 1.20A 1sguA-2idcA:
undetectable		 1sguA-2idcA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.93A 1v54N-2idcA:
undetectable
1v54W-2idcA:
undetectable		 1v54N-2idcA:
13.97
1v54W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.84A 1v55A-2idcA:
undetectable
1v55J-2idcA:
undetectable		 1v55A-2idcA:
13.97
1v55J-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.87A 1v55N-2idcA:
undetectable
1v55W-2idcA:
undetectable		 1v55N-2idcA:
13.97
1v55W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 2dyrN-2idcA:
undetectable
2dyrW-2idcA:
undetectable		 2dyrN-2idcA:
13.97
2dyrW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.89A 2eijN-2idcA:
undetectable
2eijW-2idcA:
undetectable		 2eijN-2idcA:
13.97
2eijW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.88A 2eikN-2idcA:
undetectable
2eikW-2idcA:
undetectable		 2eikN-2idcA:
13.97
2eikW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.85A 2eilN-2idcA:
undetectable
2eilW-2idcA:
undetectable		 2eilN-2idcA:
13.97
2eilW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.79A 2einA-2idcA:
undetectable
2einJ-2idcA:
undetectable		 2einA-2idcA:
13.97
2einJ-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.93A 2einN-2idcA:
undetectable
2einW-2idcA:
undetectable		 2einN-2idcA:
13.97
2einW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 3abkA-2idcA:
undetectable
3abkJ-2idcA:
undetectable		 3abkA-2idcA:
13.97
3abkJ-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.94A 3ablA-2idcA:
undetectable
3ablJ-2idcA:
undetectable		 3ablA-2idcA:
13.97
3ablJ-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 3ablN-2idcA:
undetectable
3ablW-2idcA:
undetectable		 3ablN-2idcA:
13.97
3ablW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.88A 3abmN-2idcA:
undetectable
3abmW-2idcA:
undetectable		 3abmN-2idcA:
13.97
3abmW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.89A 3ag1N-2idcA:
undetectable
3ag1W-2idcA:
undetectable		 3ag1N-2idcA:
13.97
3ag1W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.91A 3ag3A-2idcA:
undetectable
3ag3J-2idcA:
undetectable		 3ag3A-2idcA:
13.97
3ag3J-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 3ag3N-2idcA:
undetectable
3ag3W-2idcA:
undetectable		 3ag3N-2idcA:
13.97
3ag3W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.91A 3asnN-2idcA:
undetectable
3asnW-2idcA:
undetectable		 3asnN-2idcA:
13.97
3asnW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 3asoN-2idcA:
undetectable
3asoW-2idcA:
undetectable		 3asoN-2idcA:
13.97
3asoW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		3 / 3 PRO A  21
SER A  75
ASN A  13
 None
 0.71A 3lslG-2idcA:
undetectable		 3lslG-2idcA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.97A 3wg7N-2idcA:
undetectable
3wg7W-2idcA:
undetectable		 3wg7N-2idcA:
13.97
3wg7W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 LYS A  10
LEU A  12
THR A  27
SER A  75
 None
 1.02A 4pwjA-2idcA:
2.6		 4pwjA-2idcA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 4 ILE A  95
ILE A 139
ARG A 137
LEU A  97
 None
 1.09A 5dzkh-2idcA:
undetectable
5dzkn-2idcA:
undetectable
5dzkv-2idcA:
undetectable		 5dzkh-2idcA:
23.00
5dzkn-2idcA:
23.00
5dzkv-2idcA:
2.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.88A 5iy5A-2idcA:
undetectable
5iy5J-2idcA:
undetectable		 5iy5A-2idcA:
13.97
5iy5J-2idcA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.97A 5z86N-2idcA:
undetectable
5z86W-2idcA:
undetectable		 5z86N-2idcA:
13.97
5z86W-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.93A 5zcoN-2idcA:
undetectable
5zcoW-2idcA:
undetectable		 5zcoN-2idcA:
13.97
5zcoW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.92A 5zcpN-2idcA:
undetectable
5zcpW-2idcA:
undetectable		 5zcpN-2idcA:
13.97
5zcpW-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 6nmfA-2idcA:
undetectable
6nmfJ-2idcA:
undetectable		 6nmfA-2idcA:
13.97
6nmfJ-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.93A 6nmpA-2idcA:
undetectable
6nmpJ-2idcA:
undetectable		 6nmpA-2idcA:
13.97
6nmpJ-2idcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2idc ANTI-SILENCING
PROTEIN 1 AND
HISTONE H3 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 5 ILE A   9
ARG A 108
THR A  43
LEU A  42
 None
 0.90A 6nmpN-2idcA:
undetectable
6nmpW-2idcA:
undetectable		 6nmpN-2idcA:
13.97
6nmpW-2idcA:
19.57