SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2idv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.83A 1rtsB-2idvA:
undetectable		 1rtsB-2idvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		5 / 8 ALA A 165
ILE A 121
ILE A 194
GLY A 181
ILE A 180
 None
 1.50A 1sh9A-2idvA:
undetectable		 1sh9A-2idvA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.77A 2tsrA-2idvA:
undetectable		 2tsrA-2idvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 8 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.84A 2tsrB-2idvA:
undetectable		 2tsrB-2idvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		3 / 3 ASP A 148
THR A  74
GLU A  43
 None
 0.69A 2zifB-2idvA:
undetectable		 2zifB-2idvA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		3 / 3 CYH A  99
HIS A  98
PHE A 100
 None
 1.15A 3cr4X-2idvA:
undetectable		 3cr4X-2idvA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		5 / 11 PHE A 131
LEU A 188
TRP A 184
CYH A 123
ASP A 192
 None
 1.37A 4fr8A-2idvA:
undetectable		 4fr8A-2idvA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.76A 4iqqA-2idvA:
undetectable		 4iqqA-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.69A 4iqqB-2idvA:
undetectable		 4iqqB-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.71A 4iqqC-2idvA:
undetectable		 4iqqC-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 8 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.73A 4iqqD-2idvA:
undetectable		 4iqqD-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.71A 5h3aA-2idvA:
undetectable		 5h3aA-2idvA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.78A 5h3aB-2idvA:
undetectable		 5h3aB-2idvA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.76A 5nooA-2idvA:
undetectable		 5nooA-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 7 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.72A 5nooB-2idvA:
undetectable		 5nooB-2idvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2idv EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-1
(Triticum
aestivum) 		4 / 8 ILE A 166
ASP A 148
GLY A 147
PHE A 144
 None
 0.73A 5nooD-2idvA:
undetectable		 5nooD-2idvA:
18.35