SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 6 ILE A 124
LYS A 133
ALA A 135
MET A 144
 None
 1.00A 1hk2A-2ieeA:
undetectable		 1hk2A-2ieeA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 8 TYR A  49
PRO A 106
SER A 232
LEU A 237
 None
 0.76A 3lsfH-2ieeA:
17.3		 3lsfH-2ieeA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		3 / 3 TYR A 157
ASP A 175
ASP A 168
 None
 0.81A 3r24A-2ieeA:
undetectable		 3r24A-2ieeA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 8 GLU A  52
GLU A  56
LYS A  59
ARG A  60
 None
 1.21A 4bqfB-2ieeA:
undetectable		 4bqfB-2ieeA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 6 ASP A  90
ASN A  89
TYR A  49
ASP A 180
 None
 1.21A 4mdaA-2ieeA:
undetectable		 4mdaA-2ieeA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		3 / 3 SER A  28
ALA A  26
VAL A  25
 None
 0.56A 4o2bA-2ieeA:
undetectable		 4o2bA-2ieeA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		3 / 3 SER A  28
ALA A  26
VAL A  25
 None
 0.63A 4o2bC-2ieeA:
undetectable		 4o2bC-2ieeA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		5 / 12 TYR A 107
VAL A  65
LEU A 220
LEU A 228
LEU A 237
 None
 1.36A 4rtbA-2ieeA:
undetectable		 4rtbA-2ieeA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		5 / 12 LEU A 178
ILE A 177
GLY A 137
THR A 140
LEU A 130
 None
 1.24A 5nfjC-2ieeA:
undetectable		 5nfjC-2ieeA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 7 TYR A 182
TYR A 181
GLN A 209
ASP A  90
 None
 1.48A 5ov9B-2ieeA:
undetectable		 5ov9B-2ieeA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 2iee PROBABLE ABC
TRANSPORTER
EXTRACELLULAR-BINDIN
G PROTEIN YCKB
(Bacillus
subtilis) 		4 / 6 GLU A  50
ALA A  87
LEU A 211
TYR A 107
 None
 1.10A 5phhA-2ieeA:
undetectable		 5phhA-2ieeA:
20.75