SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2if2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2if2 DEPHOSPHO-COA KINASE
(Aquifex
aeolicus) 		4 / 8 ILE A 172
CYH A  12
GLY A  13
CYH A 137
 None
SO4  A 301 (-4.9A)
SO4  A 301 (-3.5A)
None
 0.80A 1sv9A-2if2A:
undetectable		 1sv9A-2if2A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 2if2 DEPHOSPHO-COA KINASE
(Aquifex
aeolicus) 		4 / 7 TYR A  27
ARG A  22
PHE A 108
ILE A  98
 None
 1.22A 2zseA-2if2A:
7.9		 2zseA-2if2A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2if2 DEPHOSPHO-COA KINASE
(Aquifex
aeolicus) 		5 / 12 TYR A  92
ILE A 109
GLY A   5
ALA A 168
ALA A 112
 None
 1.02A 3jb3A-2if2A:
undetectable		 3jb3A-2if2A:
10.96