SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2if6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		3 / 3 VAL A 193
VAL A  87
TRP A  19
 None
 0.84A 1av2A-2if6A:
undetectable
1av2B-2if6A:
undetectable		 1av2A-2if6A:
8.27
1av2B-2if6A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		3 / 3 VAL A 193
VAL A  87
TRP A  19
 None
 0.74A 1w5uA-2if6A:
undetectable
1w5uB-2if6A:
undetectable		 1w5uA-2if6A:
8.27
1w5uB-2if6A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		3 / 3 VAL A  87
TRP A  19
VAL A 193
 None
 0.71A 2izqC-2if6A:
undetectable
2izqD-2if6A:
undetectable		 2izqC-2if6A:
8.27
2izqD-2if6A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		4 / 8 GLU A 130
SER A 129
ARG A 143
VAL A 184
 UNX  A   1 (-2.2A)
None
None
None
 1.35A 3nlyA-2if6A:
undetectable
3nlyB-2if6A:
undetectable		 3nlyA-2if6A:
18.89
3nlyB-2if6A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		4 / 8 GLU A 130
SER A 129
ARG A 143
VAL A 184
 UNX  A   1 (-2.2A)
None
None
None
 1.36A 3rqlA-2if6A:
undetectable
3rqlB-2if6A:
undetectable		 3rqlA-2if6A:
18.89
3rqlB-2if6A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		4 / 7 VAL A  62
TRP A  77
ILE A  78
TRP A  19
 None
 1.18A 4xo7B-2if6A:
undetectable		 4xo7B-2if6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		4 / 5 ALA A  65
TYR A 115
PRO A 181
PHE A 119
 None
 1.22A 4ze2A-2if6A:
undetectable		 4ze2A-2if6A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		4 / 6 VAL A  54
THR A  23
LEU A 111
GLU A 130
 None
None
None
UNX  A   1 (-2.2A)
 0.96A 5tudD-2if6A:
undetectable		 5tudD-2if6A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		3 / 3 TYR A  47
ALA A 187
LEU A 190
 None
 0.63A 6ag0C-2if6A:
undetectable		 6ag0C-2if6A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2if6 HYPOTHETICAL PROTEIN
YIIX
(Escherichia
coli) 		3 / 3 GLN A 137
TRP A 133
VAL A 144
 None
 0.82A 6auuA-2if6A:
undetectable		 6auuA-2if6A:
18.89