SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2if7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 2if7 SLAM FAMILY MEMBER 6
(Homo
sapiens) 		4 / 8 PRO A  51
HIS A  54
ILE A  53
ILE A  31
 None
 0.94A 3sfeB-2if7A:
undetectable
3sfeC-2if7A:
undetectable		 3sfeB-2if7A:
16.41
3sfeC-2if7A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 2if7 SLAM FAMILY MEMBER 6
(Homo
sapiens) 		4 / 7 VAL A 159
TRP A 144
LEU A 151
SER A 152
 None
 0.81A 4zphA-2if7A:
undetectable
4zphB-2if7A:
undetectable		 4zphA-2if7A:
21.07
4zphB-2if7A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 2if7 SLAM FAMILY MEMBER 6
(Homo
sapiens) 		4 / 5 ASN A  65
GLN A  73
SER A  75
ARG A  63
 None
 1.46A 5w4zA-2if7A:
undetectable		 5w4zA-2if7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2if7 SLAM FAMILY MEMBER 6
(Homo
sapiens) 		3 / 3 MET A  79
ASP A 137
ARG A 109
 None
 1.07A 5z6jA-2if7A:
undetectable		 5z6jA-2if7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2if7 SLAM FAMILY MEMBER 6
(Homo
sapiens) 		3 / 3 MET A  79
ASP A 137
ARG A 109
 None
 1.10A 5z6kA-2if7A:
undetectable		 5z6kA-2if7A:
21.72