SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ifd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 2ifd M-PHASE INDUCER
PHOSPHATASE 2
(Homo
sapiens) 		4 / 8 CYH A 473
TYR A 528
ARG A 479
TYR A 512
 SO4  A 551 (-3.9A)
None
SO4  A 551 (-3.9A)
None
 1.47A 1xqlA-2ifdA:
undetectable
1xqlB-2ifdA:
undetectable		 1xqlA-2ifdA:
18.94
1xqlB-2ifdA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ifd M-PHASE INDUCER
PHOSPHATASE 2
(Homo
sapiens) 		4 / 4 PRO A 457
LEU A 454
ILE A 487
ARG A 488
 None
 1.33A 3w1wA-2ifdA:
3.0		 3w1wA-2ifdA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ifd M-PHASE INDUCER
PHOSPHATASE 2
(Homo
sapiens) 		4 / 9 CYH A 426
ALA A 449
LEU A 469
ILE A 423
 None
 0.93A 4xtaA-2ifdA:
undetectable		 4xtaA-2ifdA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ifd M-PHASE INDUCER
PHOSPHATASE 2
(Homo
sapiens) 		3 / 3 ARG A 544
LEU A 540
PHE A 536
 None
 0.65A 6nknP-2ifdA:
undetectable		 6nknP-2ifdA:
21.51